Kilian‐Simon Baumann
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View article: Impact of dose rate and its definition on the production of hydrogen peroxide in pure water
Impact of dose rate and its definition on the production of hydrogen peroxide in pure water Open
Introduction. The clinical interest in particle therapy continues to grow due to its precise dose distribution and increased biological effectiveness. Recent attention has focused on ultra high dose rate (UHDR) irradiation, which has been …
View article: Corrigendum to “Proton and Carbon Ion Beam Spot Size Measurement Using 5 Different Detector Types” [Int J Part Ther. 2025;15:100638]
Corrigendum to “Proton and Carbon Ion Beam Spot Size Measurement Using 5 Different Detector Types” [Int J Part Ther. 2025;15:100638] Open
View article: Monte Carlo simulation of beam quality correction factor <i>k<sub>Q</sub> </i> for carbon-ion beams using FLUKA and GATE for selected cylindrical and plane-parallel ionization chambers
Monte Carlo simulation of beam quality correction factor <i>k<sub>Q</sub> </i> for carbon-ion beams using FLUKA and GATE for selected cylindrical and plane-parallel ionization chambers Open
Objective . To benchmark Monte Carlo codes FLUKA and GATE/Geant4 regarding the beam quality correction factors of ionization chambers for monoenergetic carbon-ion beams against experimental results by Holm et al (2022 Phys. Med. Biol. 67 4…
View article: Effect of Protons on HPV-neg. and HPV-pos. HNSCC cell lines and its enhancement by PARP inhibitors Olaparib and Talazoparib
Effect of Protons on HPV-neg. and HPV-pos. HNSCC cell lines and its enhancement by PARP inhibitors Olaparib and Talazoparib Open
View article: Proton and Carbon Ion Beam Spot Size Measurement Using 5 Different Detector Types
Proton and Carbon Ion Beam Spot Size Measurement Using 5 Different Detector Types Open
The study concludes that, although a single Gaussian fit is generally sufficient for QA, more sophisticated models might be beneficial for special applications. These findings aim to guide detector selection for ion beam facilities, enhanc…
View article: Investigating the impact of the effective point of measurement for plane-parallel ionization chambers in clinical proton beams
Investigating the impact of the effective point of measurement for plane-parallel ionization chambers in clinical proton beams Open
Objective. To investigate the impact of the positioning of plane-parallel ionization chambers in proton beams on the calculation of the chamber-specific factor f Q and, hence, the beam quality correction factor . Approach. Monte …
View article: Impact of nuclear fragmentation on the stopping power ratio of <sup>12</sup>C ion beams
Impact of nuclear fragmentation on the stopping power ratio of <sup>12</sup>C ion beams Open
Objective : Nuclear fragmentation generates a diverse dosimetric environment in the path of 12 C ion beams. Concise parametrization of the beam’s composition is paramount for determining key correction factors in clinical dosimetry. This s…
View article: On the Way to Accounting for Lung Modulation Effects in Particle Therapy of Lung Cancer Patients—A Review
On the Way to Accounting for Lung Modulation Effects in Particle Therapy of Lung Cancer Patients—A Review Open
Particle therapy presents a promising alternative to conventional photon therapy for treating non-small cell lung cancer (NSCLC). However, the heterogeneous structure of lung tissue leads to the degradation of the Bragg peak and thereby to…
View article: Evaluation of a prototype array for daily quality assurance in spot scanning proton therapy
Evaluation of a prototype array for daily quality assurance in spot scanning proton therapy Open
Background Quality assurance (QA) on a daily basis is an essential task in radiotherapy. In pencil beam scanning proton therapy (PBS), there is a lack of available practical QA devices for routine daily QA in comparison to conventional rad…
View article: PROTON AND CARBON ION SPOT SIZE MEASUREMENT COMPARISON USING FOUR DIFFERENT DETECTOR TYPES
PROTON AND CARBON ION SPOT SIZE MEASUREMENT COMPARISON USING FOUR DIFFERENT DETECTOR TYPES Open
View article: DOSIMETRIC EVALUATION OF A SYNCHROTON-BASED PROTON AND CARBON ION BEAMLINE FOR FLASH EXPERIMENTS
DOSIMETRIC EVALUATION OF A SYNCHROTON-BASED PROTON AND CARBON ION BEAMLINE FOR FLASH EXPERIMENTS Open
View article: EXPERIMENTAL VERIFICATION OF THE RADIOLYSIS IN THE CHEMICAL PHASE IN GEANT4-DNA
EXPERIMENTAL VERIFICATION OF THE RADIOLYSIS IN THE CHEMICAL PHASE IN GEANT4-DNA Open
View article: Fano cavity test and investigation of the response of the Roos chamber irradiated by proton beams in perpendicular magnetic fields up to 1 T
Fano cavity test and investigation of the response of the Roos chamber irradiated by proton beams in perpendicular magnetic fields up to 1 T Open
Objective . The aim of this work is to investigate the response of the Roos chamber (type 34001) irradiated by clinical proton beams in magnetic fields. Approach . At first, a Fano test was implemented in Monte Carlo software package GATE …
View article: Comparison of two methods simulating inter-track interactions using the radiobiological Monte Carlo toolkit TOPAS-nBio
Comparison of two methods simulating inter-track interactions using the radiobiological Monte Carlo toolkit TOPAS-nBio Open
Objective. To compare two independently developed methods that enable modelling inter-track interactions in TOPAS-nBio by examining the yield of radiolytic species in radiobiological Monte Carlo track structure simulations. One method uses…
View article: Consistency of Faraday cup and ionization chamber dosimetry of proton fields and the role of nuclear interactions
Consistency of Faraday cup and ionization chamber dosimetry of proton fields and the role of nuclear interactions Open
Background A Faraday cup (FC) facilitates a quite clean measurement of the proton fluence emerging from clinical spot‐scanning nozzles with narrow pencil‐beams. The utilization of FCs appears to be an attractive option for high dose rate d…
View article: The influence of different versions of FLUKA and GEANT4 on the calculation of response functions of ionization chambers in clinical proton beams
The influence of different versions of FLUKA and GEANT4 on the calculation of response functions of ionization chambers in clinical proton beams Open
Objective. To investigate the influence of different versions of the Monte Carlo codes geant 4 and fluka on the calculation of overall response functions f Q of air-filled ionization chambers in clinical proton beams. Approach. f Q factors…
View article: Proton dosimetry in a magnetic field: Measurement and calculation of magnetic field correction factors for a plane‐parallel ionization chamber
Proton dosimetry in a magnetic field: Measurement and calculation of magnetic field correction factors for a plane‐parallel ionization chamber Open
Background The combination of magnetic resonance imaging and proton therapy offers the potential to improve cancer treatment. The magnetic field (MF)‐dependent change in the dosage of ionization chambers in magnetic resonance imaging‐integ…
View article: Monte Carlo calculated ionization chamber correction factors in clinical proton beams – deriving uncertainties from published data
Monte Carlo calculated ionization chamber correction factors in clinical proton beams – deriving uncertainties from published data Open
View article: A method to implement inter-track interactions in Monte Carlo simulations with TOPAS-nBio and their influence on simulated radical yields following water radiolysis
A method to implement inter-track interactions in Monte Carlo simulations with TOPAS-nBio and their influence on simulated radical yields following water radiolysis Open
Objective. In FLASH radiotherapy (dose rates ≥40 Gy s −1 ), a reduced normal tissue toxicity has been observed, while maintaining the same tumor control compared to conventional radiotherapy (dose rates ≤0.03 Gy s −1 ). This protecting eff…
View article: Carbon Ion Beam Boost Irradiation in Malignant Tumors of the Nasal Vestibule and the Anterior Nasal Cavity as an Organ-Preserving Therapy
Carbon Ion Beam Boost Irradiation in Malignant Tumors of the Nasal Vestibule and the Anterior Nasal Cavity as an Organ-Preserving Therapy Open
Background Surgery and radiotherapy are current therapeutic options for malignant tumors involving the nasal vestibule. Depending on the location, organ-preserving resection is not always possible, even for small tumors. Definitive radioth…
View article: Experimental determination of modulation power of lung tissue for particle therapy
Experimental determination of modulation power of lung tissue for particle therapy Open
In particle therapy of lung tumors, modulating effects on the particle beam may occur due to the microscopic structure of the lung tissue. These effects are caused by the heterogeneous nature of the lung tissue and cannot be completely tak…
View article: Compensating for beam modulation due to microscopic lung heterogeneities in carbon ion therapy treatment planning
Compensating for beam modulation due to microscopic lung heterogeneities in carbon ion therapy treatment planning Open
Purpose : To predict and mitigate for the degradation in physical and biologically effective dose distributions of particle beams caused by microscopic heterogeneities in lung tissue. Materials and Methods : The TRiP98 treatment planning s…
View article: Investigating the feasibility of TOPAS-nBio for Monte Carlo track structure simulations by adapting GEANT4-DNA examples application
Investigating the feasibility of TOPAS-nBio for Monte Carlo track structure simulations by adapting GEANT4-DNA examples application Open
Purpose. The purpose of this work is to investigate the feasibility of TOPAS-nBio for track structure simulations using tuple scoring and ROOT/Python-based post-processing. Materials and methods. There are several example applications impl…
View article: Estimating the modulating effect of lung tissue in particle therapy using a clinical CT voxel histogram analysis
Estimating the modulating effect of lung tissue in particle therapy using a clinical CT voxel histogram analysis Open
To treat lung tumours with particle therapy, different additional tasks and challenges in treatment planning and application have to be addressed thoroughly. One of these tasks is the quantification and consideration of the Bragg peak (BP)…
View article: Analyzing the modulation effects of lung tissue in proton therapy
Analyzing the modulation effects of lung tissue in proton therapy Open
Nicht-kleinzelliger Lungenkrebs ist weltweit die häufigste krebsbedingte Todesursache. Darüber hinaus ist anzunehmen, dass die Inzidenz und Mortalität aufgrund von Rauchen, der zunehmenden Umweltverschmutzung und der alternden Bevölkerung …
View article: Correction to: Effects of the Bragg peak degradation due to lung tissue in proton therapy of lung cancer patients
Correction to: Effects of the Bragg peak degradation due to lung tissue in proton therapy of lung cancer patients Open
View article: Monte Carlo calculation of beam quality correction factors in proton beams using TOPAS/GEANT4
Monte Carlo calculation of beam quality correction factors in proton beams using TOPAS/GEANT4 Open
To provide Monte Carlo calculated beam quality correction factors ( k Q ) for monoenergetic proton beams using , a toolkit based on the Monte Carlo code . Monte Carlo simulations of six plane-parallel and four cylindrical ionization chambe…
View article: Effects of the Bragg peak degradation due to lung tissue in proton therapy of lung cancer patients
Effects of the Bragg peak degradation due to lung tissue in proton therapy of lung cancer patients Open
View article: Advantage of proton-radiotherapy for pediatric patients and adolescents with Hodgkin’s disease
Advantage of proton-radiotherapy for pediatric patients and adolescents with Hodgkin’s disease Open
View article: Comparison of <scp>penh</scp>, <scp>fluka</scp>, and Geant4/<scp>topas</scp> for absorbed dose calculations in air cavities representing ionization chambers in high‐energy photon and proton beams
Comparison of <span>penh</span>, <span>fluka</span>, and Geant4/<span>topas</span> for absorbed dose calculations in air cavities representing ionization chambers in high‐energy photon and proton beams Open
Purpose The purpose of this work is to analyze whether the Monte Carlo codes penh , fluka , and geant4/topas are suitable to calculate absorbed doses and ratios in therapeutic high‐energy photon and proton beams. Methods We used penh , flu…