Kim Eiden
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View article: Protocol using ex vivo mouse brain slice culture mimicking in vivo conditions to study tumor growth and cell motility of glioblastoma cells
Protocol using ex vivo mouse brain slice culture mimicking in vivo conditions to study tumor growth and cell motility of glioblastoma cells Open
Herein, we present an ex vivo approach to study glioblastoma (GBM) cell motility in viable mouse brain slice cultures, closely mimicking in vivo features. We detail the preparation and culturing of mouse brain slices followed by tumor cell…
View article: Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells Open
View article: Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis Open
View article: Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis Open
Progression of primary cancer to metastatic disease is the most common cause of death in cancer patients with minimal treatment options available. Canonical drugs target mainly the proliferative capacity of cancer cells, which often leaves…