Young‐Mo Kim
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View article: Feasibility and Safety of an Outdoor-Simulated Interactive Indoor Cycling Device for Cardiac Rehabilitation: A Pilot Validation Study
Feasibility and Safety of an Outdoor-Simulated Interactive Indoor Cycling Device for Cardiac Rehabilitation: A Pilot Validation Study Open
Background/Objectives: To examine the safety and clinical applicability of a newly developed outdoor-simulated interactive indoor cycling device as a potential exercise modality for cardiac rehabilitation (CR) in patients with cardiovascul…
View article: Enabling malic acid production from corn-stover hydrolysate in Lipomyces starkeyi via metabolic engineering and bioprocess optimization
Enabling malic acid production from corn-stover hydrolysate in Lipomyces starkeyi via metabolic engineering and bioprocess optimization Open
Together, this work demonstrated the ability to produce organic acids in L. starkeyi with minimal byproducts. The fermentation characterization and omic analyses provide a rich dataset for understanding L. starkeyi physiology and metabolic…
View article: Retrobiosynthesis of unnatural lactams via reprogrammed polyketide synthase
Retrobiosynthesis of unnatural lactams via reprogrammed polyketide synthase Open
Engineered polyketide synthases (PKSs) have great potential as biocatalysts. These unnatural enzymes are capable of synthesizing molecules that are either not amenable to biosynthesis or are extremely challenging to access chemically. PKSs…
View article: Holo‐omics disentangle drought response and biotic interactions among plant, endophyte and pathogen
Holo‐omics disentangle drought response and biotic interactions among plant, endophyte and pathogen Open
Summary Holo‐omics provide a novel opportunity to study the interactions among fungi from different functional guilds in host plants in field conditions. We address the entangled responses of plant pathogenic and endophytic fungi associate…
View article: A Low Life’s Simple 7 Score Is an Independent Risk Factor for Postoperative Delirium After Total Knee Arthroplasty
A Low Life’s Simple 7 Score Is an Independent Risk Factor for Postoperative Delirium After Total Knee Arthroplasty Open
Background and Objectives: Postoperative delirium (PODil) is a cognitive condition characterized by sudden fluctuations in consciousness and orientation after surgery. PODil following total knee arthroplasty (TKA) is associated with prolon…
View article: Cyanobacterial circadian regulation enhances bioproduction under subjective nighttime through rewiring of carbon partitioning dynamics, redox balance orchestration, and cell cycle modulation
Cyanobacterial circadian regulation enhances bioproduction under subjective nighttime through rewiring of carbon partitioning dynamics, redox balance orchestration, and cell cycle modulation Open
Background The industrial feasibility of photosynthetic bioproduction using cyanobacterial platforms remains challenging due to insufficient yields, particularly due to competition between product formation and cellular carbon demands acro…
View article: Phenylpropanoid methyl esterase unlocks catabolism of aromatic biological nitrification inhibitors
Phenylpropanoid methyl esterase unlocks catabolism of aromatic biological nitrification inhibitors Open
Microbial nitrification of fertilizers represents is a significant global source of greenhouse gas emissions. This process increases emissions, fosters toxic algal blooms, and raises crop production costs. Some plants naturally release bio…
View article: Accelerating polyketide synthase engineering for high TRY production of biofuels and bioproducts (Final Technical Report)
Accelerating polyketide synthase engineering for high TRY production of biofuels and bioproducts (Final Technical Report) Open
Polyketide synthase (PKS) enzymes have a modular, deterministic logic that holds the potential to act as a flexible chemical factory for the biological production of a huge diversity of valuable small molecule compounds. However, engineeri…
View article: The impact of heat stress on the human plasma lipidome
The impact of heat stress on the human plasma lipidome Open
The year of 2023 displayed the highest average global temperatures since it has been recorded—the duration and severity of extreme heat are projected to increase. Rising global temperatures represent a major public health threat, especiall…
View article: The impact of heat stress on the human plasma lipidome
The impact of heat stress on the human plasma lipidome Open
The year of 2023 displayed the highest average global temperatures since it has been recorded—the duration and severity of extreme heat are projected to increase. Rising global temperatures represent a major public health threat, especiall…
View article: A multi-omic survey of black cottonwood tissues highlights coordinated transcriptomic and metabolomic mechanisms for plant adaptation to phosphorus deficiency
A multi-omic survey of black cottonwood tissues highlights coordinated transcriptomic and metabolomic mechanisms for plant adaptation to phosphorus deficiency Open
Introduction Phosphorus (P) deficiency in plants creates a variety of metabolic perturbations that decrease photosynthesis and growth. Phosphorus deficiency is especially challenging for the production of bioenergy feedstock plantation spe…