Kinga Rutowicz
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View article: Linker Histones Enhance Robustness in Diurnal Transcription Dynamics
Linker Histones Enhance Robustness in Diurnal Transcription Dynamics Open
Linker histone H1 is crucial for chromatin organization and gene expression in Arabidopsis thaliana , influencing development and stress responses. To explore its role in diurnal gene regulation, we examined H1-deficient plants and found t…
View article: Pre-meiotic H1.1 degradation is essential for Arabidopsis gametogenesis
Pre-meiotic H1.1 degradation is essential for Arabidopsis gametogenesis Open
Despite being evolutionary distant, plants and animals share a common phenomenon at the somatic-to-reproductive cell fate transition with extensive structural and compositional changes in chromatin. Such chromatin reprogramming occurs in t…
View article: Linker histones enhance robustness in diurnal transcription dynamics
Linker histones enhance robustness in diurnal transcription dynamics Open
Linker histone H1 is crucial for chromatin organization and gene expression in Arabidopsis thaliana , influencing development and stress responses. To explore its role in diurnal gene regulation, we examined H1-deficient plants and found t…
View article: Multiscale chromatin dynamics and high entropy in plant iPSC ancestors
Multiscale chromatin dynamics and high entropy in plant iPSC ancestors Open
Plant protoplasts provide starting material for of inducing pluripotent cell masses that are competent for tissue regeneration in vitro, analogous to animal induced pluripotent stem cells (iPSCs). Dedifferentiation is associated with large…
View article: Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon
Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon Open
Long terminal repeat retrotransposons (LTR-RTs) are powerful mutagens regarded as a major source of genetic novelty and important drivers of evolution. Yet, the uncontrolled and potentially selfish proliferation of LTR-RTs can lead to dele…
View article: Multiscale chromatin dynamics and high entropy in plant iPSC ancestors
Multiscale chromatin dynamics and high entropy in plant iPSC ancestors Open
Plant protoplasts constitute the starting material to induce pluripotent cell masses in vitro competent for tissue regeneration. Dedifferentiation is associated with large-scale chromatin reorganisation and massive transcriptome reprogramm…
View article: Transposition of<i>HOPPLA</i>in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in<i>Brachypodium distachyon</i>
Transposition of<i>HOPPLA</i>in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in<i>Brachypodium distachyon</i> Open
Long terminal repeat retrotransposons (LTR-RTs) are powerful mutagens regarded as a major source of genetic novelty and important drivers of evolution. Yet, the uncontrolled and potentially selfish proliferation of LTR-RTs can lead to dele…
View article: EvoChromo: towards a synthesis of chromatin biology and evolution
EvoChromo: towards a synthesis of chromatin biology and evolution Open
Over the past few years, interest in chromatin and its evolution has grown. To further advance these interests, we organized a workshop with the support of The Company of Biologists to debate the current state of knowledge regarding the or…
View article: Additional file 5: of Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis
Additional file 5: of Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis Open
Table S4. Gene expression in 3h1. Available as an Excel table. (XLSX 4453 kb)
View article: Additional file 3: of Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis
Additional file 3: of Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis Open
Table S2. Transposable element (TE) expression in 3h1. Available as an Excel table. (XLSX 64 kb)
View article: Linker histones regulate fine-scale chromatin organization and modulate developmental decisions in Arabidopsis
Linker histones regulate fine-scale chromatin organization and modulate developmental decisions in Arabidopsis Open
Chromatin in eukaryotes provides a tunable platform to control gene expression and convey an epigenetic memory throughout cell divisions. H1 linker histones are abundant components with an intrinsic potential in influencing chromatin struc…
View article: Phylogeny-Based Systematization of Arabidopsis Proteins with Histone H1 Globular Domain
Phylogeny-Based Systematization of Arabidopsis Proteins with Histone H1 Globular Domain Open
H1 (or linker) histones are basic nuclear proteins that possess an evolutionarily conserved nucleosome-binding globular domain, GH1. They perform critical functions in determining the accessibility of chromatin DNA to trans-acting factors.…
View article: A Pragmatic Approach to Getting Published: 35 Tips for Early Career Researchers
A Pragmatic Approach to Getting Published: 35 Tips for Early Career Researchers Open
It is trite to say "publish or perish," yet many early career researchers are often at a loss on how to best get their work published. With strong competition and many manuscripts submitted, it is difficult to convince editors and reviewer…
View article: Histone H1 Variants in Arabidopsis Are Subject to Numerous Post-Translational Modifications, Both Conserved and Previously Unknown in Histones, Suggesting Complex Functions of H1 in Plants
Histone H1 Variants in Arabidopsis Are Subject to Numerous Post-Translational Modifications, Both Conserved and Previously Unknown in Histones, Suggesting Complex Functions of H1 in Plants Open
Linker histones (H1s) are conserved and ubiquitous structural components of eukaryotic chromatin. Multiple non-allelic variants of H1, which differ in their DNA/nucleosome binding properties, co-exist in animal and plant cells and have bee…
View article: A specialized histone H1 variant is required for adaptive responses to complex abiotic stress and related DNA methylation in Arabidopsis
A specialized histone H1 variant is required for adaptive responses to complex abiotic stress and related DNA methylation in Arabidopsis Open
Linker (H1) histones play critical roles in chromatin compaction in higher eukaryotes. They are also the most variable of the histones, with numerous nonallelic variants cooccurring in the same cell. Plants contain a distinct subclass of m…