Explanipedia

The Impact of Sleep on Neurologic and Neurocognitive Complications in Children With Sickle Cell Disease: A Scoping Review Open

Robert H. Rice, Ambika G. Chidambaram, Kiran Nandalike, Shaina M. Willen · 2025

Sleep‐disordered breathing (SDB), characterized by sleep fragmentation and hypoxia, is a prevalent yet underappreciated complication in children with sickle cell disease (SCD). The interplay between SDB and neurologic outcomes in SCD, incl…

0995 Adherence to CPAP Therapy in Children: Findings from a Respiratory Therapist Driven CPAP Clinic Open

Audrey Chikalla, Ambika G. Chidambaram, Leigherin Hurd, Kiran Nandalike · 2025

Introduction There is an increasing number of children needing continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) but the adherence to CPAP therapy remains less than 50% in children. Our sleep center imple…

1501 Sleepy Teens: A Case Series of Diagnostic Dilemmas in Pathological Excessive Daytime Sleepiness (EDS) Open

Katyayini Aribindi, Kiran Nandalike, Ambika G. Chidambaram · 2025

Introduction Central disorders for hypersomnolence (CDH) consist of idiopathic hypersomnia (IH), narcolepsy type 1 and type 2. These are difficult to differentiate due to confounding social issues and mood disorders commonly encountered in…

1465 Refractory Obstructive Sleep Apnea in Children with Rubinstein-Taybi Syndrome Open

JS Ahn, Kiran Nandalike, Ambika G. Chidambaram · 2025

Introduction Rubinstein-Taybi Syndrome (RTS) is a rare genetic condition characterized by distinctive broad and/or angled fingers and toes, craniofacial dysmorphism, short stature, and global developmental delay. The studies in adults with…

Sleep-related breathing disorders in children with spina bifida Open

Kiran Nandalike, Laura Hobart‐Porter · 2024

Purpose The objective of this article was to explore the prevalence, pathophysiology, diagnosis, and management of sleep-related breathing disorders (SRBDs) in children with spina bifida and specifically myelomeningocele (MMC). Summary SRB…

Sleep Disordered Breathing in Children with Neuromuscular Disease Open

Ambika G. Chidambaram, Sanjay Jhawar, Craig M. McDonald, Kiran Nandalike · 2023

Sleep disordered breathing (SDB) in children with neuromuscular disease (NMD) is more prevalent compared to the general population, and often manifests as sleep-related hypoventilation, sleep-related hypoxemia, obstructive sleep apnea, cen…

Clinical Characteristics and Post-Operative Outcomes in Children with Very Severe Obstructive Sleep Apnea Open

Nancy Saied, Roberto N. Solis, Jamie L. Funamura, Joy Chen, Cathleen Lammers , et al. · 2022

Available information on clinical characteristics and post-operative outcomes in children with very severe obstructive sleep apnea (OSA) is limited. Our study evaluates the clinical features and polysomnographic (PSG) variables that predic…

Associations between sleep, obesity, and asthma in urban minority children Open

Laura A. Conrad, Kiran Nandalike, Seema Rani, Deepa Rastogi · 2022

Conrad LA, Nandalike K, Rani S, Rastogi D. Associations between sleep, obesity, and asthma in urban minority children. J Clin Sleep Med. 2022;18(10):2377-2385.

548: Evaluation of elexacaftor/tezacaftor/ivacaftor on pulmonary function in cystic fibrosis patients Open

Abdullah Hamad, Danielle Hiner, Vicki Jue, Yan Shi, S. Stoffella , et al. · 2021

831 Diagnostic and Treatment Challenges in a Child with Type 1 Narcolepsy Open

Sirish Nakka, Kiran Nandalike · 2021

Introduction The diagnosis and management of Narcolepsy can be challenging in young children. We present a case of abrupt onset severe type 1 narcolepsy complicated by tactile hallucinations with stimulant medication therapy. Report of cas…

Nasal trumpet as a long-term remedy for obstructive sleep apnea syndrome in a child Open

Tammy Yau, Ruchi Bansal, Kimberly A. Hardin, Craig W. Senders, Kiran Nandalike · 2021

We present a case of successful long-term use of nasal trumpet for severe obstructive sleep apnea syndrome in a child with cerebral palsy and complex medical issues. Obstructive sleep apnea syndrome is frequently seen in pediatric patients…

Utility of Mid‐Upper Arm Circumference in Diagnosing Malnutrition in Children With Cystic Fibrosis Open

Rachel Y. Phong, Sandra L. Taylor, Brandt A. Robinson, Sanjay Jhawar, Kiran Nandalike · 2020

Background Standardized diagnostic indicators for malnutrition using growth percentile z‐ scores (weight for length or body mass index [BMI]) and mid‐upper arm circumference (MUAC) z‐ scores are being used in clinical practice; however, th…

Adolescent with Acute Eosinophilic Pneumonia with Acute Respiratory Failure Associated with Multifactorial Inhalational Substance Use Open

Sumío Hirata, Kiran Nandalike, Rory Kamerman‐Kretzmer, Michelle Han · 2020

Vaping in today’s pandemic: E-cigarette, or vaping, product use–associated lung injury mimicking COVID-19 in teenagers presenting with respiratory distress Open

Daphne O. Darmawan, Kriti Gwal, Brian D. Goudy, Sanjay Jhawar, Kiran Nandalike · 2020

The clinical presentation of children and adolescents infected with severe acute respiratory syndrome coronavirus 2 can range from asymptomatic to mild or moderate manifestations. We present a case series of three adolescents who presented…

The Feasibility and Utility of Level III Portable Sleep Studies in the Pediatric Inpatient Setting Open

Gurinder Singh, Kimberly A. Hardin, Heejung Bang, Kiran Nandalike · 2019

The level III portable sleep study is readily available, sufficient to diagnose SDB, and help to provide appropriate medical and/or surgical therapies in hospitalized children with complex medical conditions.

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