Kirill Miachin
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View article: A dual MTOR/NAD+ acting gerotherapy
A dual MTOR/NAD+ acting gerotherapy Open
The geroscience hypothesis states that a therapy that prevents the underlying aging process should prevent multiple aging related diseases. The mTOR (mechanistic target of rapamycin)/insulin and NAD+ (nicotinamide adenine dinucleotide) pat…
View article: CCDC 2089526: Experimental Crystal Structure Determination
CCDC 2089526: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Intracellular Localization Studies of the Luminescent Analogue of an Anticancer Ruthenium Iminophosphorane with High Efficacy in a Triple-Negative Breast Cancer Mouse Model
Intracellular Localization Studies of the Luminescent Analogue of an Anticancer Ruthenium Iminophosphorane with High Efficacy in a Triple-Negative Breast Cancer Mouse Model Open
The potential of ruthenium(II) compounds as an alternative to platinum-based clinical anticancer agents has been unveiled after extensive research for over 2 decades. As opposed to cisplatin, ruthenium(II) compounds have distinct mechanism…
View article: CCDC 1882280: Experimental Crystal Structure Determination
CCDC 1882280: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1882281: Experimental Crystal Structure Determination
CCDC 1882281: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Preparation of Titanocene–Gold Compounds Based on Highly Active Gold(I)‐<i>N</i>‐Heterocyclic Carbene Anticancer Agents: Preliminary in vitro Studies in Renal and Prostate Cancer Cell Lines
Preparation of Titanocene–Gold Compounds Based on Highly Active Gold(I)‐<i>N</i>‐Heterocyclic Carbene Anticancer Agents: Preliminary in vitro Studies in Renal and Prostate Cancer Cell Lines Open
Heterometallic titanocene‐based compounds containing gold(I)‐phosphane fragments have been extremely successful against renal cancer in vitro and in vivo. The exchange of phosphane by N ‐heterocyclic carbene ligands to improve or modulate …