Kirshan Lal
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View article: Advances in endoscopic techniques for early detection and treatment of gastrointestinal cancers: A systematic review
Advances in endoscopic techniques for early detection and treatment of gastrointestinal cancers: A systematic review Open
Background: The early detection and treatment of gastrointestinal cancers are critical for improving patient outcomes. These techniques include white light endoscopy (WLE), chromoendoscopy, i-scan, flexible spectral imaging color enhanceme…
View article: ACE Inhibitors and ARBs in Chronic Kidney Disease: A Systematic Review of Randomized Controlled Trials on Albuminuria Reduction, eGFR Decline, and Safety
ACE Inhibitors and ARBs in Chronic Kidney Disease: A Systematic Review of Randomized Controlled Trials on Albuminuria Reduction, eGFR Decline, and Safety Open
This article highlights the favorable renal outcomes achieved through optimized renin-angiotensin-aldosterone system (RAAS) blockade in an adult patient with chronic kidney disease (CKD) and significant proteinuria. Sustained therapy led t…
View article: Mechanistic Insights Into the Cardioprotective Effects of Modern Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review
Mechanistic Insights Into the Cardioprotective Effects of Modern Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review Open
Type 2 diabetes mellitus (T2DM) is closely linked to increased cardiovascular risk through mechanisms involving oxidative stress, adverse cardiac remodeling, and endothelial dysfunction. While glucose-lowering therapies improve glycemic co…
View article: Evaluating the Renal Implications of Intensive Versus Standard Blood Pressure Control in Chronic Kidney Disease: A Systematic Review of Randomized Trials
Evaluating the Renal Implications of Intensive Versus Standard Blood Pressure Control in Chronic Kidney Disease: A Systematic Review of Randomized Trials Open
View article: Long-Term Proton Pump Inhibitor Use and the Risk of Kidney Disease, Dementia, and Fractures: A Systematic Review
Long-Term Proton Pump Inhibitor Use and the Risk of Kidney Disease, Dementia, and Fractures: A Systematic Review Open
Chronic use of proton pump inhibitors (PPIs), although effective for acid-related disorders, has raised concerns regarding their association with various long-term adverse health outcomes. This systematic review aimed to synthesize evidenc…
View article: Choosing the Right Vasoactive Agent in Acute Variceal Bleeding in Cirrhotic Patients: A Review of Terlipressin vs. Octreotide Outcomes
Choosing the Right Vasoactive Agent in Acute Variceal Bleeding in Cirrhotic Patients: A Review of Terlipressin vs. Octreotide Outcomes Open
View article: Frequency of Subclinical Hypothyroidism in Women With Polycystic Ovary Syndrome
Frequency of Subclinical Hypothyroidism in Women With Polycystic Ovary Syndrome Open
View article: Impact of Coronavirus Diseases on Liver Enzymes
Impact of Coronavirus Diseases on Liver Enzymes Open
Introduction Coronavirus disease 2019 (COVID-19) affects various organs including lungs, brain, and eyes. Very limited data is available related to the effect of COVID-19 on liver. This study is conducted to determine the impact of COVID-1…
View article: Comparison of Lipid Profile in Patients With and Without Subclinical Hypothyroidism
Comparison of Lipid Profile in Patients With and Without Subclinical Hypothyroidism Open
In conclusion, this study found an increased incidence of dyslipidemias in patients with SCH. It is associated with elevated TC and LDL levels, which are risk factors for cardiovascular disease and mortality.
View article: Colon biopsies: benefit or burden?
Colon biopsies: benefit or burden? Open
Analyzing colon biopsies is becoming time consuming and a financial burden as colonoscopy is now the main screening and diagnostic procedure of the main gastrointestinal diseases. Colon sampling can provide important information when used …