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View article: Integrated Transcriptomic Analysis of S100A8/A9 as a Key Biomarker and Therapeutic Target in Sepsis Pathogenesis and AI Drug Repurposing
Integrated Transcriptomic Analysis of S100A8/A9 as a Key Biomarker and Therapeutic Target in Sepsis Pathogenesis and AI Drug Repurposing Open
Sepsis is a life-threatening condition driven by a dysregulated immune response, leading to systemic inflammation and multi-organ failure. Among the key molecular regulators, S100A8/A9 has emerged as a critical damage-associated molecular …
View article: AI for Computational Biology: Highlights from the first BioAI Hackathon at University of Warsaw
AI for Computational Biology: Highlights from the first BioAI Hackathon at University of Warsaw Open
The BioAI Hackathon at the Centre of New Technologies at the University of Warsaw convened 43 international researchers to collaboratively explore artificial intelligence (AI) approaches for solving complex challenges in computational biol…
View article: IL-1R2 as a Precision Therapeutic Target in Sepsis: Molecular Insights into Immune Regulation
IL-1R2 as a Precision Therapeutic Target in Sepsis: Molecular Insights into Immune Regulation Open
Sepsis is a life-threatening condition characterized by systemic inflammation and organ dysfunction, with a complex and not yet fully elucidated molecular basis. Central to its pathogenesis is a dysregulated immune response. In this study,…
View article: Identification of blast resistant finger millet (Eleusine coracana L.) genotype through phenotypic screening and molecular profiling
Identification of blast resistant finger millet (Eleusine coracana L.) genotype through phenotypic screening and molecular profiling Open
View article: Omics-based analysis of mitochondrial dysfunction and BBB integrity in post-COVID-19 sequelae
Omics-based analysis of mitochondrial dysfunction and BBB integrity in post-COVID-19 sequelae Open
View article: Genomic strategies for drug repurposing
Genomic strategies for drug repurposing Open
Functional genomics, a multidisciplinary subject, investigates the functions of genes and their products in biological systems to better understand diseases and find new drugs. Drug repurposing is an economically efficient approach that en…
View article: RNA-Seq analysis of human heart tissue reveals SARS-CoV-2 infection and inappropriate activation of the TNF-NF-κB pathway in cardiomyocytes
RNA-Seq analysis of human heart tissue reveals SARS-CoV-2 infection and inappropriate activation of the TNF-NF-κB pathway in cardiomyocytes Open
View article: Climate Change Impacts on Legume Physiology and Ecosystem Dynamics: A Multifaceted Perspective
Climate Change Impacts on Legume Physiology and Ecosystem Dynamics: A Multifaceted Perspective Open
As valuable sources of plant-based protein, leguminous vegetables (grain legumes) are essential for global food security and contribute to body growth and development in humans as well as animals. Climate change is a major challenge for ag…
View article: Sustainable Biotechnology Approaches Using Chlorella vulgaris's Biomass and Lipids as Biofuel Feedstock
Sustainable Biotechnology Approaches Using Chlorella vulgaris's Biomass and Lipids as Biofuel Feedstock Open
Chlorella vulgaris has considerable promise as a raw material for biofuel production since it has a high productivity per unit area, has a minimum influence on the environment, and does not significantly affect food security. Nevertheless,…
View article: Genomic Approaches for Drug Repurposing
Genomic Approaches for Drug Repurposing Open
Functional genomics, a multidisciplinary subject, investigates the functions of genes and their products in biological systems to better understand diseases and find new drugs. Drug repurposing is an economically efficient approach that en…
View article: A systematic study of molecular targets of cannabidiol in Alzheimer's disease
A systematic study of molecular targets of cannabidiol in Alzheimer's disease Open
Background Alzheimer's disease (AD) is a prevalent, incurable, and chronic neurodegenerative condition characterized by the accumulation of amyloid-β protein (Aβ), disrupting various bodily systems. Despite the lack of a cure, phenolic com…
View article: ELIXIR and Toxicology: a community in development
ELIXIR and Toxicology: a community in development Open
Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into t…
View article: Comparative transcriptome analysis elucidates positive physiological effects of foliar application of pyraclostrobin on tomato (Solanum lycopersicum L.)
Comparative transcriptome analysis elucidates positive physiological effects of foliar application of pyraclostrobin on tomato (Solanum lycopersicum L.) Open
View article: ELIXIR and Toxicology: a community in development
ELIXIR and Toxicology: a community in development Open
Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into t…
View article: <strong><em>MetAlgNet :</em></strong>Metabolic pathway network reconstruction from algae genome annotation data.
<strong><em>MetAlgNet :</em></strong>Metabolic pathway network reconstruction from algae genome annotation data. Open
Post-genomic molecular biology embodies high-throughput experimental techniques and hence it is a data-rich field. The goal of development of this tool is to utilize free available biological data of green algae in order to produce new met…