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View article: Effects of Carnosine Supplementation on Cognitive Outcomes in Prediabetes and Well-Controlled Type 2 Diabetes: A Randomised Placebo-Controlled Clinical Trial
Effects of Carnosine Supplementation on Cognitive Outcomes in Prediabetes and Well-Controlled Type 2 Diabetes: A Randomised Placebo-Controlled Clinical Trial Open
Background: Trends in global ageing underscore the rising burden of age-related cognitive decline and concomitant cardiometabolic diseases, including type 2 diabetes mellitus (T2DM). Carnosine, a naturally occurring dipeptide with anti-inf…
View article: Carnosine Did Not Affect Vascular and Metabolic Outcomes in Patients with Prediabetes and Type 2 Diabetes: A 14-Week Randomized Controlled Trial
Carnosine Did Not Affect Vascular and Metabolic Outcomes in Patients with Prediabetes and Type 2 Diabetes: A 14-Week Randomized Controlled Trial Open
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality in patients with prediabetes and type 2 diabetes mellitus (T2DM). Carnosine has been suggested as a potential approach to reduce ASCVD risk fact…
View article: Carnosine supplementation improves glucose control in adults with pre-diabetes and type 2 diabetes: A randomised controlled trial
Carnosine supplementation improves glucose control in adults with pre-diabetes and type 2 diabetes: A randomised controlled trial Open
This study provides preliminary support for larger trials evaluating carnosine as a potential treatment for prediabetes and the initial stages of T2DM. Likely mechanisms may include changes to hepatic glucose output explaining the observed…
View article: Carnosine supplementation improves glucose control in adults with pre-diabetes and type 2 diabetes: a randomised controlled trial
Carnosine supplementation improves glucose control in adults with pre-diabetes and type 2 diabetes: a randomised controlled trial Open
Type 2 diabetes (T2DM) is a major cause of morbidity and mortality globally. Carnosine, a naturally occurring dipeptide, has anti-inflammatory, antioxidant, and anti-glycating effects, with preliminary evidence suggesting it may improve im…
View article: Estimating the benefits of obesity prevention on productivity: an Australian perspective
Estimating the benefits of obesity prevention on productivity: an Australian perspective Open
Background/objectives Obesity poses one of the biggest public health challenges globally. In addition to the high costs of obesity to the healthcare system, obesity also impacts work productivity. We aimed to estimate the benefits of preve…
View article: The Cost-Effectiveness of Supplemental Carnosine in Type 2 Diabetes
The Cost-Effectiveness of Supplemental Carnosine in Type 2 Diabetes Open
In this paper, we assess the cost-effectiveness of 1 g daily of carnosine (an over the counter supplement) in addition to standard care for the management of type 2 diabetes and compare it to standard care alone. Dynamic multistate life ta…
View article: Use of carnosine in the prevention of cardiometabolic risk factors in overweight and obese individuals: study protocol for a randomised, double-blind placebo-controlled trial
Use of carnosine in the prevention of cardiometabolic risk factors in overweight and obese individuals: study protocol for a randomised, double-blind placebo-controlled trial Open
Introduction Carnosine, an over the counter food supplement, has been shown to improve glucose metabolism as well as cardiovascular risk factors in animal and human studies through its anti-inflammatory, antioxidative, antiglycating and ch…
View article: Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis
Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis Open
OBJECTIVE Diabetes imposes a heavy burden on both health and productivity. In this study, we sought to estimate the potential productivity gains associated with the prevention of type 2 diabetes over the next 10 years in Australia. RESEARC…
View article: Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis
Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis Open
Objective: Diabetes imposes a heavy burden on both health and productivity. In this study, we sought to estimate the potential productivity gains associated with the prevention of type 2 diabetes over the next ten years in Australia…
View article: Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis
Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis Open
Objective: Diabetes imposes a heavy burden on both health and productivity. In this study, we sought to estimate the potential productivity gains associated with the prevention of type 2 diabetes over the next ten years in Australia…
View article: Low-cost Interventions for Prevention of Metabolic Diseases
Low-cost Interventions for Prevention of Metabolic Diseases Open
The work in this thesis focuses on the burden of chronic diseases, specifically obesity and type 2 diabetes mellitus have on health and its impact on work productivity. Additionally, cost-effectiveness analyses of two low-cost intervention…
View article: THU0496 Skeletal deficit due to altered bone quality in type 1 diabetes mellitus
THU0496 Skeletal deficit due to altered bone quality in type 1 diabetes mellitus Open
View article: Effects of supplementation with carnosine and other histidine-containing dipeptides on chronic disease risk factors and outcomes: protocol for a systematic review of randomised controlled trials
Effects of supplementation with carnosine and other histidine-containing dipeptides on chronic disease risk factors and outcomes: protocol for a systematic review of randomised controlled trials Open
Introduction Ageing of populations globally, coupled with the obesity epidemic, has resulted in the rising prevalence of chronic diseases including diabetes, cardiovascular diseases, cancers and neurodegenerative disorders. Prevention of r…
View article: Shared Medical Appointments May Be Effective for Improving Clinical and Behavioral Outcomes in Type 2 Diabetes: A Narrative Review
Shared Medical Appointments May Be Effective for Improving Clinical and Behavioral Outcomes in Type 2 Diabetes: A Narrative Review Open
Type 2 diabetes mellitus (T2DM) is a complex chronic disease affecting over 400 million people worldwide. Managing T2DM and its associated complications in individual patient consultations poses substantial challenges to physicians due to …
View article: Does supplementation with carnosine improve cardiometabolic health and cognitive function in patients with pre-diabetes and type 2 diabetes? study protocol for a randomised, double-blind, placebo-controlled trial
Does supplementation with carnosine improve cardiometabolic health and cognitive function in patients with pre-diabetes and type 2 diabetes? study protocol for a randomised, double-blind, placebo-controlled trial Open
Introduction Carnosine, an over-the-counter food supplement, has a promising potential for the prevention and treatment of chronic diseases such as type 2 diabetes (T2DM), cardiovascular and neurodegenerative diseases through its anti-infl…
View article: Group Studio Cycling; an Effective Intervention to Improve Cardio-Metabolic Health in Overweight Physically Inactive Individuals
Group Studio Cycling; an Effective Intervention to Improve Cardio-Metabolic Health in Overweight Physically Inactive Individuals Open
Introduction: Supervised, laboratory based studies of high intensity interval training (HIIT) is effective\nat improving health markers in groups at risk of cardiovascular and metabolic disease. Studio cycling,\nincorporating aerobic and h…