Kamlesh Khunti
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View article: 97 Fostering inclusive research partnerships: empowering marginalised communities
97 Fostering inclusive research partnerships: empowering marginalised communities Open
EP1.4, e-Poster Terminal 1, September 4, 2025, 11:35 - 13:00 Aim To co-produce research collaboration and allyship with marginalised communities and voluntary sector organisations and pave the way for novel approaches to advancing public i…
View article: Risk prediction in people with acute myocardial infarction in England: a cohort study using data from 1521 general practices
Risk prediction in people with acute myocardial infarction in England: a cohort study using data from 1521 general practices Open
Objective To develop prediction models for short-term outcomes following a first acute myocardial infarction (AMI) event (index) or for past AMI events (prevalent) in a national primary care cohort. Design Retrospective cohort study using …
View article: Interventions to Improve Medication Adherence in People With Hypertension: Protocol for a Systematic Review and Meta‐Analysis
Interventions to Improve Medication Adherence in People With Hypertension: Protocol for a Systematic Review and Meta‐Analysis Open
Background and Aims Medication adherence is the extent to which a patient's behavior corresponds with the prescriber's recommendations for taking medications. Non‐adherence is particularly high in patients with hypertension, leading to poo…
View article: Improving medication adherence in type 2 diabetes: strategies for better clinical and economic outcomes
Improving medication adherence in type 2 diabetes: strategies for better clinical and economic outcomes Open
Medication adherence is critical for optimal glycaemic management and the prevention of complications in type 2 diabetes mellitus. Despite its importance, non-adherence remains a prevalent issue, with global estimates suggesting that appro…
View article: Trajectories of type 2 diabetes and cancer in 330 000 individuals with prediabetes: 20-year observational study in England
Trajectories of type 2 diabetes and cancer in 330 000 individuals with prediabetes: 20-year observational study in England Open
National Institute for Health and Care Research (NIHR) Applied Research Collaboration, East Midlands, NIHR Leicester British Retail Consortium, Hope Against Cancer.
View article: The Role of Adaptive and Innovative Trial Designs in Diabetes Research: A Scoping Review
The Role of Adaptive and Innovative Trial Designs in Diabetes Research: A Scoping Review Open
BACKGROUND Adaptive and master protocol clinical trials offer significant advantages for diabetes research, including enhanced efficiency and personalized treatment strategies. PURPOSE This scoping review aimed to systematically map the us…
View article: Sociodemographic intersections and risk of multiple long-term conditions: A systematic review
Sociodemographic intersections and risk of multiple long-term conditions: A systematic review Open
Multimorbidity, or multiple long-term conditions (MLTC), is a growing public health concern with implications for quality of life, healthcare utilisation, and premature mortality. Classical explanations for MLTC often treat sociodemographi…
View article: Optimizing lipid-lowering therapy for acute coronary syndrome using a decision support system: insights from a cluster randomized trial
Optimizing lipid-lowering therapy for acute coronary syndrome using a decision support system: insights from a cluster randomized trial Open
Aims Lipid-lowering therapy (LLT) after acute coronary syndrome (ACS) typically follows stepwise intensification, delaying use of combination therapies and low-density lipoprotein cholesterol (LDL-C) goal attainment. We assessed whether ac…
View article: Prevalence of cardiometabolic diseases in Sub-Saharan Africa: a systematic review and meta-analysis
Prevalence of cardiometabolic diseases in Sub-Saharan Africa: a systematic review and meta-analysis Open
Cardiometabolic diseases (CMDs) are increasingly prevalent in Sub-Saharan Africa (SSA), underscoring the need to understand the existing public health burden. This would guide future policy strategies and interventions to mitigate the chal…
View article: Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England: a retrospective, population-based cohort study using linked electronic health records
Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England: a retrospective, population-based cohort study using linked electronic health records Open
Wellcome Trust, British Heart Foundation Data Science Centre, and Health Data Research UK.
View article: Which demographic characteristics are associated with willingness to take part in recontact studies? A cross-sectional study
Which demographic characteristics are associated with willingness to take part in recontact studies? A cross-sectional study Open
Background Lower rates of participation in research by ethnic minority groups and socioeconomically deprived populations has led to efforts to develop recruitment strategies which aim to address this imbalance. Little is known about partic…
View article: Who presents the greatest challenge in intellectual disability research- participants or health and research professionals?
Who presents the greatest challenge in intellectual disability research- participants or health and research professionals? Open
Background The challenges of recruitment to randomised controlled trials have been well documented. The additional challenges of recruiting people with intellectual disabilities (ID) and significant health co-morbidities have been the focu…
View article: Proteomics insights: exploring the inflammatory and metabolic signatures of ethnicity and change in physical activity in non-diabetic hyperglycaemia
Proteomics insights: exploring the inflammatory and metabolic signatures of ethnicity and change in physical activity in non-diabetic hyperglycaemia Open
NIHR Leicester Biomedical Research Centre.
View article: Blood pressure and adverse cardiovascular outcomes in older people with type 2 diabetes and chronic kidney disease: Findings based on the Clinical Practice Research Datalink databases in England
Blood pressure and adverse cardiovascular outcomes in older people with type 2 diabetes and chronic kidney disease: Findings based on the Clinical Practice Research Datalink databases in England Open
Aims Managing blood pressure (BP) in older adults with type 2 diabetes (T2D) and chronic kidney disease (CKD) remains controversial, particularly regarding optimal targets and the impact of inadequate monitoring. Using Clinical Practice Re…
View article: Burden of cardiovascular diseases in England (2020–24): a national cohort using electronic health records data
Burden of cardiovascular diseases in England (2020–24): a national cohort using electronic health records data Open
British Heart Foundation Data Science Centre (Health Data Research UK).
View article: Outpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK
Outpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK Open
Objectives We aimed to estimate how rheumatology outpatient hospital attendances have changed since the COVID-19 pandemic and determine demographic characteristics associated with observed changes. Methods Using three primary and secondary…
View article: The Diagnostic Accuracy of Biological Markers of Sarcopenia, Sarcopenic Obesity, and Osteosarcopenia: Protocol for a Systematic Review and Meta‐Analysis
The Diagnostic Accuracy of Biological Markers of Sarcopenia, Sarcopenic Obesity, and Osteosarcopenia: Protocol for a Systematic Review and Meta‐Analysis Open
Background and Aims Sarcopenia is the accelerated loss of skeletal muscle mass and function associated with aging, and can significantly impact a person's quality of life. Sarcopenia can also occur with other health conditions, such as exc…
View article: Sometimes different, often the same: guidance on how recruitment and retention in trials need to be tailored to enhance participation of ethnic minority groups: a qualitative interview study in England
Sometimes different, often the same: guidance on how recruitment and retention in trials need to be tailored to enhance participation of ethnic minority groups: a qualitative interview study in England Open
We spoke with 20 adults from a range of ethnic backgrounds across England. Participants emphasized that clear, honest communication and respect for different cultures and languages are essential. Many preferred receiving information from t…
View article: A cohort description and comparison of four European national diabetes registries for the <scp>REDDIE</scp> project
A cohort description and comparison of four European national diabetes registries for the <span>REDDIE</span> project Open
Aims The Real‐world Evidence for Decisions in Diabetes (REDDIE) project aims to better understand how to use real‐world data (RWD) to advance research related to diabetes. To achieve this aim, four national registries (National Diabetes Au…
View article: Association between the English National Health Service Diabetes Prevention Programme and incident multiple long-term conditions
Association between the English National Health Service Diabetes Prevention Programme and incident multiple long-term conditions Open
Existing evaluations of the National Health Service Diabetes Prevention Programme (NHS DPP) in England have demonstrated associated reductions in body weight, hemoglobin A1c and incident type 2 diabetes (T2D). In this study, we examined as…
View article: Prescription distribution and inequities in diabetes care: A comparative analysis of continuous glucose monitoring access by diabetes status, ethnicity and socio‐economic factors in England
Prescription distribution and inequities in diabetes care: A comparative analysis of continuous glucose monitoring access by diabetes status, ethnicity and socio‐economic factors in England Open
Background Diabetes affects over 3.3 million people in England, creating a significant health and economic burden. Continuous glucose monitoring (CGM) improves diabetes management but remains unevenly accessible, especially among Black and…
View article: Co-creating community engagement and involvement strategies: understanding challenges and needs of people living with multiple long-term conditions and stakeholders’ perspectives in India and Nepal
Co-creating community engagement and involvement strategies: understanding challenges and needs of people living with multiple long-term conditions and stakeholders’ perspectives in India and Nepal Open
Living with multiple long-term conditions (MLTCs) presents significant healthcare and patient-level challenges, which are further compounded by fragmented and poorly coordinated healthcare systems, leading to difficulties in access, dissat…