Explanipedia

Knowledge, Attitude, and Practice of Sickle Cell Disease Among Sickle Cell Disease Patients in Sudurpashchim Province of Nepal: A Cross‐Sectional Study Open

G.R. Joshi, Sher Bahadur Kamar, Pradip Mishra, Hemraj Pandey, Sandesh Rimal , et al. · 2025

Background Sickle cell disease (SCD) is a genetic hemoglobinopathy which is responsible for about 3.5% of deaths in < 5 years age of children. It is a global health issue particularly affecting the native tribe or backwards community like …

Zoonotic risks arising from the exotic pet trade Open

Sarita Phuyal, R.T. Wilson, Sher Bahadur Pun, Rajendra Prasad Parajuli, Kishor Pandey · 2025

Socio-Demographic Characteristics and Clinical profile in Sickle Cell Disease Patients Open

G.R. Joshi, Sher Bahadur Kamar, Pradip Mishra, Hem Raj Pandey, Yogendra Shah , et al. · 2025

Background: Sickle cell disease (SCD) is a significant public health issue in Nepal, predominantly affecting the Tharu community in the Mid-Western and Sudurpaschim province. This study was design to understand the socio-demographic charac…

From vaccination success to new outbreaks: reassessing Japanese encephalitis control in Nepal Open

Krishna Prasad Acharya, Francesco Branda, Sarita Phuyal, Massimo Ciccozzi, Fabio Scarpa , et al. · 2025

Why did rabies control fail in low-income and middle-income countries? Open

Krishna Prasad Acharya, Sarita Phuyal, R.T. Wilson, Narayan Acharya, Sher Bahadur Pun , et al. · 2025

Seroprevalence and associated behavioral factors of Toxoplasma gondii infection among pregnant women in Pokhara Valley, Nepal Open

Mamata Thapa, Tulsi Ram Gompo, Tatsuki Sugi, Masahito Asada, Hiroaki Arima , et al. · 2025

Background Toxoplasma gondii is a protozoan parasite that can cause congenital infections with serious health implications. In pregnant women, T. gondii infection poses significant risks, including miscarriage, stillbirth, and congenital a…

Cholera in Nepal: policy priorities and regional lessons Open

Francesco Branda, Hemraj Kandu, Kishor Pandey, Sher Bahadur Pun, Krishna Acharya · 2025

Potential Risk of Local Transmission of Mpox in Nepal: An Emerging Public Health Concern Open

Yogendra Shah, Ankit Kumar Singh, Bipin Kumar Acharya, Mandira Lamichhane Dhimal, Ram Singh Dhami , et al. · 2025

Background and Aims Monkeypox (Mpox) is a zoonotic disease caused by the monkeypox virus, a double‐stranded DNA virus of the Orthopoxvirus genus with two major clades (Clades I and II), with Clade IIb responsible for most global cases repo…

Canine Demodicosis in Rupandehi Nepal’s Street Dogs: Prevalence, Clinical Signs, and Hematology Open

Rachana Bhusal, Tulsi Ram Gompo, Tatsuki Sugi, Masahito Asada, Kishor Pandey · 2025

Canine demodicosis is a contagious skin disease caused by the over-proliferation of Demodex mites in the host’s hair follicles. This study examines the prevalence, clinical signs, and hematological changes associated with demodicosis in st…

Correction to: Prevalence and associated factors of intestinal parasitic infections in the Badi indigenous communities of Western Nepal Open

Jitendra Gautam, Rajendra Prasad Parajuli, Kishor Pandey · 2025

Intestinal Parasitic Infections and Associated Behavioral Risk Factors in a Squatter Community in Butwal, Nepal: A Pilot Study Open

Shristi Bhandari, Rajendra Prasad Parajuli, Pitambar Dhakal, Kishor Pandey · 2025

Background Intestinal parasitic infections (IPIs) are among the most prevalent illnesses worldwide. The morbidity associated with IPIs results in health and economic burdens for billions of people worldwide, especially in low‐income nation…

High Intestinal Parasite Contamination in Raw Vegetables Sold in Kathmandu Metropolitan City, Nepal Open

Zainuddin Ansari, Rajendra Prasad Parajuli, Pitambar Dhakal, Kishor Pandey · 2025

Objectives: Fresh vegetables are crucial for a healthy diet, providing the body with essential supplements. Intestinal parasites/commensals are transmitted primarily through the consumption of raw contaminated vegetables. This study aimed …

Prevalence and associated factors of intestinal parasitic infections in the Badi indigenous communities of Western Nepal Open

Jitendra Gautam, Rajendra Prasad Parajuli, Kishor Pandey · 2024

Despite years of a national deworming campaign, the incidence of intestinal parasitic infections (IPIs) remains relatively high among certain ethnic groups, with lifestyle factors distinct from those of the general population. Despite exis…

Sex differences in genotype frequency and the risk of polycythemia associated with rs13419896 and rs2790859 among Tibetan highlanders living in Tsarang, Mustang, Nepal Open

Hiroaki Arima, Takayuki Nishimura, Sweta Koirala, Masayuki Nakano, Hiromu Ito , et al. · 2024

Background Tibetan highlanders have adapted to hypoxic environments through genetic mechanisms that avoid hemoglobin concentration increases and prevent polycythemia. Recently, sex differences in hemoglobin dynamics with age have been repo…

Current and future predicted distribution of roosts of the Indian Flying Fox Pteropus medius Temmink, 1825 in Nepal Open

Sanjan Thapa, Dibya Raj Dahal, Suraj Baral, Kishor Pandey, Tej Bahadur Thapa , et al. · 2024

The Indian Flying Fox Pteropus medius, largest of the four fruit bat species in Nepal and is extensively distributed in South Asia. Their known roosts are distributed within an elevation range of 75 to 1,322 m asl east to west in the Tarai…

Prevalence of intestinal parasites in humans and domestic animals in Jirel community, Dolakha, Nepal Open

Pitambar Dhakal, Medhavi Dhakal, Dipa Dhakal, Pramita Shakya, Barsha Singh , et al. · 2024

A BSTRACT Introduction: Gastrointestinal (GI) parasites are major health concerns in both humans and domestic animals. Livestock farming is one of the common livelihood practices in rural Nepal. The proximity at human and domestic animal i…

Molecular and Entomological Characterization of 2023 Dengue Outbreak in Dhading District, Central Nepal Open

Sandesh Rimal, Sabin Shrestha, Sunita Wagle Paudel, Yogendra Shah, Govinda Bhandari , et al. · 2024

In 2023, Nepal faced its second largest dengue outbreak ever, following a record-breaking number of dengue cases in 2022, characterized by the expansion of infections into areas of higher altitudes. However, the characteristics of the 2023…

Anxiety and its risk factors among non-Japanese residents living in Japan undergoing COVID-19 situation: A cross-sectional survey Open

Mai Luu, Atsuko Imoto, Yoshimi Matsuo, Nguyen Tien Huy, Ahmad Taysir Atieh Qarawi , et al. · 2024

Introduction In the context of collective efforts taken in Japan to control the spread of COVID-19, the state of emergency and social distancing have caused a negative impact on the mental health of all residents, including foreign communi…

Association of RT-qPCR Ct Values and Disease Severity among COVID-19 Patients Visiting a Tertiary Care Hospital in Nepal Open

Jagadish Joshi, O. P. Joshi, Sher Bahadur Kamar, Guna Raj Awasthi, Yogendra Shah , et al. · 2024

COVID-19 pandemic due to SARS-CoV-2 has been one of the major global health issues of this aeon. The aim of this study was to evaluate the association of SARS-CoV-2 cycle threshold (Ct) values with multiple factors among COVID-19 patients …

Intestinal helminth parasites of Felis catus in Syangja, Nepal Open

Navina Sharma, Janak Raj Subedi, Muna Thapa, Kishor Pandey · 2024

Domestic cats can be infested by a huge range of parasite species, leading to a range of diverse clinical signs and symptoms. However, a comprehensive understanding of these endoparasites, particularly in the context of multiparasitism, re…

Current and future predicted distribution range of Indian Flying Fox Pteropus medius Temmink, 1825 in Nepal Open

Sanjan Thapa, Dibya Raj Dahal, Suraj Baral, Kishor Pandey, Tej Bahadur Thapa , et al. · 2023

Pteropus medius is exclusively distributed in South Asia. Among four species of fruit bats occurring in Nepal, the Indian Flying Fox is the largest of all. Their known roosts are distributed within an elevation range of 75 to 1,322 m asl t…

Molecular Detection and Identification of Piroplasm in Cattle from Kathmandu Valley, Nepal Open

Medhavi Dhakal, Tulsi Ram Gompo, Prakash Devkota, Sharmila Chapagain Kafle, Janak Raj Subedi , et al. · 2023

Background: Tick-borne protozoan parasites (TBPPs) cause significant problems for domestic animals’ health in Nepal. TBPPs are routinely diagnosed by labor-intensive blood smear microscopy. In Nepal, there are some reports of Babesia and T…

Possible high risk of transmission of the Nipah virus in South and South East Asia: a review Open

Jagadish Joshi, Yogendra Shah, Kishor Pandey, Ram Prashad Ojha, Chet Raj Joshi , et al. · 2023

Leishmania donovani persistence and circulation causing cutaneous leishmaniasis in unusual-foci of Nepal Open

Tinmaya Rai, Srijan Lal Shrestha, Sabita Prajapati, Anup Bastola, Niraj Parajuli , et al. · 2023

Cutaneous leishmaniasis cases have increased dramatically in recent years in Nepal. The study offers molecular identification of the Leishmania species using 40 patient’s aspiration biopsy samples, targeting markers kinetoplast minicircle …

Leishmania donovani persistence and transmission causing cutaneous leishmaniasis in unusual-foci of Nepal Open

Tinmaya Rai, Srijan Lal Shrestha, Sabita Prajapati, Anup Bastola, Niraj Parajuli , et al. · 2023

Cutaneous leishmaniasis cases have increased dramatically in recent years in Nepal. The study offers molecular identification of the Leishmania species using 40 patient's aspiration biopsy samples, targeting markers kinetoplast minicircle …

Co-Circulation of Dengue Virus Serotypes 1, 2, and 3 during the 2022 Dengue Outbreak in Nepal: A Cross-Sectional Study Open

Sandesh Rimal, Sabin Shrestha, Kishor Pandey, Thanh Vu Nguyen, Parmananda Bhandari , et al. · 2023

The largest dengue outbreak in the history of Nepal occurred in 2022, with a significant number of casualties. It affected all 77 districts, with the nation’s capital, Kathmandu (altitude 1300 m), being the hardest hit. However, the molecu…

How an Outbreak of COVID-19 Circulated Widely in Nepal: A Chronological Analysis of the National Response to an Unprecedented Pandemic Open

Basu Dev Pandey, Mya Myat Ngwe Tun, Kishor Pandey, Shyam Prakash Dumre, Khin Mya Nwe , et al. · 2022

Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first COVID-19 case was reported in Wuhan, China, in December 2019. In March 2020, the World Health Organization (WHO) d…

High prevalence of rheumatoid arthritis and its risk factors among Tibetan highlanders living in Tsarang, Mustang district of Nepal Open

Hiroaki Arima, Sweta Koirala, Kotaro Nema, Masayuki Nakano, Hiromu Ito , et al. · 2022

Background In Tsarang (at 3560 m), which is located in Mustang, 62.7% of the residents answered that they had a subjective medical history of arthritis, and 41.1% of the residents answered that their families had a subjective medical histo…

Insights into transmission dynamics of Mycobacterium tuberculosis complex in Nepal Open

Yogendra Shah, Sarad Paudel, Kishor Pandey, G.P. Gupta, Eddie Samuneti Solo , et al. · 2022

Temporal Metabolic Profiling of Erythrocytes in Mice Infected with Babesia microti Open

Haiyan Gong, Sajid Ur Rahman, Keke Zhou, Zhibing Lin, Rongsheng Mi , et al. · 2022

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