Kiyohide Fushimi
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View article: Evaluating In-Hospital Safety and Perioperative Costs of Total Hip Arthroplasty in Super-Elderly Patients: A Nationwide Propensity Score–Matched Analysis in Japan
Evaluating In-Hospital Safety and Perioperative Costs of Total Hip Arthroplasty in Super-Elderly Patients: A Nationwide Propensity Score–Matched Analysis in Japan Open
Background: This study aimed to evaluate short-term outcomes, including in-hospital complications, mortality, and medical costs, after total hip arthroplasty (THA) in super-elderly patients aged ≥85 years compared with elderly patients age…
View article: Association between tropical cyclone exposure and stroke hospitalization: A nationwide time-series analysis in Japan
Association between tropical cyclone exposure and stroke hospitalization: A nationwide time-series analysis in Japan Open
Exposure to TCs may increase the risk of stroke, especially hemorrhagic stroke.
View article: Association between socioeconomic disadvantage and low-value care in acute care hospitals in Japan: Cross-sectional study
Association between socioeconomic disadvantage and low-value care in acute care hospitals in Japan: Cross-sectional study Open
Patients from disadvantaged areas are slightly more likely to receive low-value inpatient care than are those from non-disadvantaged areas. Older adults, women, and patients treated in non-academic hospitals appeared more affected.
View article: Trends and Determinants of Acute Tocolysis Utilization in Japan: A Nationwide Retrospective Cohort Study
Trends and Determinants of Acute Tocolysis Utilization in Japan: A Nationwide Retrospective Cohort Study Open
Background: Preterm birth remains a leading cause of neonatal mortality worldwide. While Japan has exceptionally low perinatal and neonatal mortality rates, clinical practice for preterm labor often involves maintenance tocolysis (MT) with…
View article: Association between early administration of mucoactive agents and in-hospital mortality in patients with pneumonia requiring mechanical ventilation: a nationwide cohort study
Association between early administration of mucoactive agents and in-hospital mortality in patients with pneumonia requiring mechanical ventilation: a nationwide cohort study Open
Background In patients with pneumonia requiring mechanical ventilation, increased airway secretions are associated with prolonged mechanical ventilation, but the effect of mucoactive agents remains unclear. The present study aimed to inves…
View article: Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study
Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study Open
Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. Th…
View article: Impact of enhanced hospital infection prevention measures during-COVID-19 pandemic on the incidence of surgical site infections following spinal instrumentation surgery for lumbar spinal stenosis: A nationwide database study
Impact of enhanced hospital infection prevention measures during-COVID-19 pandemic on the incidence of surgical site infections following spinal instrumentation surgery for lumbar spinal stenosis: A nationwide database study Open
Background context: Despite the implementation of stringent infection control measures during the COVID-19 pandemic, the impact of these interventions on surgical site infection (SSI) rates in spinal instrumentation surgery remains unclear…
View article: #1944 Efficacy of β-lactams versus fluoroquinolones for empirical antibiotic treatment of kidney cyst infections in polycystic kidney disease
#1944 Efficacy of β-lactams versus fluoroquinolones for empirical antibiotic treatment of kidney cyst infections in polycystic kidney disease Open
Background and Aims Kidney cyst infections are a frequent and significant complication in patients with polycystic kidney disease. Fluoroquinolones, as lipid-soluble antibiotics, are recommended for empirical therapy due to their superior …
View article: Nationwide Comparison of Cemented Versus Uncemented Hemiarthroplasty for Femoral Neck Fractures in the Elderly: A Propensity Score-Matched Analysis Using Japan's Diagnosis Procedure Combination Database
Nationwide Comparison of Cemented Versus Uncemented Hemiarthroplasty for Femoral Neck Fractures in the Elderly: A Propensity Score-Matched Analysis Using Japan's Diagnosis Procedure Combination Database Open
Cemented hemiarthroplasty significantly lowered early mechanical and thrombotic complications without increasing in-hospital mortality. Although transfusion and cerebrovascular risks were slightly elevated, cemented fixation appears to be …
View article: Impact of COVID-19 state of emergency declarations on percutaneous coronary intervention volumes in Japan: a SARIMAX analysis of nationwide DPC database (2018–2021)
Impact of COVID-19 state of emergency declarations on percutaneous coronary intervention volumes in Japan: a SARIMAX analysis of nationwide DPC database (2018–2021) Open
Objectives To evaluate the impact of Japan’s COVID-19 state of emergency declarations on percutaneous coronary intervention (PCI) volumes using Seasonal AutoRegressive Integrated Moving Average with eXogenous variables (SARIMAX) modelling.…
View article: Factors Influencing the Availability of Cardiopulmonary Exercise Testing for Patients Undergoing Cardiac Resynchronization Therapy in Japan
Factors Influencing the Availability of Cardiopulmonary Exercise Testing for Patients Undergoing Cardiac Resynchronization Therapy in Japan Open
Background This study aimed to investigate the implementation rate of cardiopulmonary exercise testing (CPET) in patients undergoing cardiac resynchronization therapy (CRT) or cardiac resynchronization therapy‐defibrillator (CRT‐D), as wel…
View article: Outcomes of continuous kidney replacement therapy versus intermittent hemodialysis in dialysis-dependent patients with acute intracerebral hemorrhage
Outcomes of continuous kidney replacement therapy versus intermittent hemodialysis in dialysis-dependent patients with acute intracerebral hemorrhage Open
In this nationwide retrospective cohort study, continuous kidney replacement therapy and intermittent hemodialysis initiated within 2 days of admission showed no significant difference in in-hospital mortality or changes in modified Rankin…
View article: Timing of surgery and outcomes in patients with congenital pulmonary airway malformation: a national inpatient database study
Timing of surgery and outcomes in patients with congenital pulmonary airway malformation: a national inpatient database study Open
Purpose The timing of elective surgery for asymptomatic congenital pulmonary airway malformation (CPAM) at birth remains controversial. We aimed to describe characteristics and outcomes of patients who underwent surgery for CPAM. Methods W…
View article: Biguanides are associated with decreased early mortality and risk of acute kidney injury in hospitalised patients with COVID-19: a nationwide retrospective cohort study in Japan
Biguanides are associated with decreased early mortality and risk of acute kidney injury in hospitalised patients with COVID-19: a nationwide retrospective cohort study in Japan Open
Background The most prescribed oral glucose-lowering medication worldwide is biguanide (BG), which shows potential for further therapeutic applications. The coronavirus disease 2019 (COVID-19) pandemic is a global public health emergency. …
View article: Effect of Oral Proton-Pump Inhibitor Administration on Reducing the Delayed Bleeding Risk in 5 Upper Gastrointestinal Endoscopic Treatments
Effect of Oral Proton-Pump Inhibitor Administration on Reducing the Delayed Bleeding Risk in 5 Upper Gastrointestinal Endoscopic Treatments Open
INTRODUCTION: Although proton-pump inhibitor (PPI) is often prescribed for reducing delayed bleeding in upper gastrointestinal endoscopic treatments, no studies with a sufficient sample size evaluated its reduced effect compared with the a…
View article: Clinical features and outcomes of peripartum obstetric patients admitted to the intensive care unit: A nationwide inpatient database in Japan
Clinical features and outcomes of peripartum obstetric patients admitted to the intensive care unit: A nationwide inpatient database in Japan Open
This was a retrospective observational study and was not registered prospectively as trial registration is not applicable to this type of study.
View article: Correction to: Risk factors associated with unplanned readmissions and frequent out-of-hour emergency department visits after pediatric tracheostomy: a nationwide inpatient database study in Japan
Correction to: Risk factors associated with unplanned readmissions and frequent out-of-hour emergency department visits after pediatric tracheostomy: a nationwide inpatient database study in Japan Open
View article: Management of inpatient chimeric antigen receptor T-cell therapy for relapsed/refractory B-cell malignancies: an analysis using the Japanese Diagnosis Procedure Combination database
Management of inpatient chimeric antigen receptor T-cell therapy for relapsed/refractory B-cell malignancies: an analysis using the Japanese Diagnosis Procedure Combination database Open
Chimeric antigen receptor T-cell (CAR-T) therapy has shown remarkable efficacy in treating relapsed/refractory B-cell malignancies, as supported by real-world evidence (RWE). However, limited RWE exists on the management of adverse events …
View article: Day and night nurse staffing levels and hospital-associated disability in older adults in Japan: a retrospective cohort study
Day and night nurse staffing levels and hospital-associated disability in older adults in Japan: a retrospective cohort study Open
Background Hospital-associated disability (HAD) in older adults often results from preventable factors. Nurse staffing at the ward level is a key modifiable factor in mitigating HAD. Objective To investigate the relationship between nurse …
View article: Association between early initiation of anti-herpesvirus therapy and outcomes in herpesvirus encephalitis: A Nationwide Retrospective Propensity Score Analysis in Japan
Association between early initiation of anti-herpesvirus therapy and outcomes in herpesvirus encephalitis: A Nationwide Retrospective Propensity Score Analysis in Japan Open
Early anti-herpesvirus therapy was associated with improved survival, functional outcomes, and lower resource utilization in HSE.
View article: Ampicillin-sulbactam versus third-generation cephalosporins in aspiration Pneumonia: A nationwide retrospective cohort study
Ampicillin-sulbactam versus third-generation cephalosporins in aspiration Pneumonia: A nationwide retrospective cohort study Open
Our findings suggest that ampicillin-sulbactam was associated with lower in-hospital mortality and a reduced incidence of C. difficile infection compared to third-generation cephalosporins in patients with aspiration pneumonia.
View article: Role of Antipseudomonal Antibiotics in Older Patients with Aspiration Pneumonia: A Nationwide Database Study in Japan
Role of Antipseudomonal Antibiotics in Older Patients with Aspiration Pneumonia: A Nationwide Database Study in Japan Open
Background: Aspiration pneumonia is increasingly recognized as a fatal pulmonary disease among older people. Although antipseudomonal antibiotics are commonly used in clinical practice, their efficacy in this population remains uncertain. …
View article: Long-term outcomes after thoracoscopic versus open surgery for congenital esophageal atresia: propensity-score overlap weighting analysis
Long-term outcomes after thoracoscopic versus open surgery for congenital esophageal atresia: propensity-score overlap weighting analysis Open
Purpose Congenital esophageal atresia requires neonatal surgery. Although short- and medium-term outcomes of thoracoscopic and open surgery have been investigated, long-term outcomes remain unclear. This study aimed to compare the long-ter…
View article: Postoperative pulmonary complications of desflurane- versus sevoflurane-based general anesthesia in patients with chronic obstructive pulmonary disease or asthma undergoing gastrointestinal cancer surgery: a nationwide retrospective cohort study
Postoperative pulmonary complications of desflurane- versus sevoflurane-based general anesthesia in patients with chronic obstructive pulmonary disease or asthma undergoing gastrointestinal cancer surgery: a nationwide retrospective cohort study Open
Purpose Desflurane and sevoflurane are widely used for general anesthesia; however, it remains uncertain if sevoflurane might be preferable for patients with chronic respiratory inflammatory diseases. This study compared postoperative outc…
View article: Epidemiology and outcomes of septic shock in Japan: a nationwide retrospective cohort study from a medical claims database by the Japan Sepsis Alliance (JaSA) study group
Epidemiology and outcomes of septic shock in Japan: a nationwide retrospective cohort study from a medical claims database by the Japan Sepsis Alliance (JaSA) study group Open
View article: Perioperative outcomes of neonatal versus delayed surgery for Hirschsprung disease: a nationwide retrospective cohort study in Japan
Perioperative outcomes of neonatal versus delayed surgery for Hirschsprung disease: a nationwide retrospective cohort study in Japan Open
View article: Tranexamic acid in total hip arthroplasty: Nationwide evidence for reducing blood transfusions and post-operative complications
Tranexamic acid in total hip arthroplasty: Nationwide evidence for reducing blood transfusions and post-operative complications Open
View article: Postoperative risks of type 2 diabetes in elderly hip fracture patients: a propensity score-matched study
Postoperative risks of type 2 diabetes in elderly hip fracture patients: a propensity score-matched study Open
Introduction Type 2 diabetes is associated with an increased risk of fragility fractures, even in individuals with normal or high bone mineral density. However, the impact of type 2 diabetes on postoperative outcomes after hip fracture sur…
View article: Perioperative antihypertensive medications and effects on functional decline and mortality in non-cardiac surgery
Perioperative antihypertensive medications and effects on functional decline and mortality in non-cardiac surgery Open
Aims The association between perioperative antihypertensive drugs and mortality as well as physical function in non-cardiac surgeries remains unclear. We aimed to clarify the association between six antihypertensive classes and postoperati…
View article: Effectiveness of antibiotic therapy for early recurrence of peritonsillar cellulitis and abscesses: a retrospective cohort study
Effectiveness of antibiotic therapy for early recurrence of peritonsillar cellulitis and abscesses: a retrospective cohort study Open