Karen Smith
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View article: Natural History of Brain Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia: A Longitudinal Neuroimaging Study
Natural History of Brain Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia: A Longitudinal Neuroimaging Study Open
Purpose: The natural history of brain arteriovenous malformations (bAVMs) in Hereditary Hemorrhagic Telangiectasia (HHT) remains poorly understood and it has been suggested that they may have a benign course different from sporadic bAVMs. …
View article: Adherence to ambulance performance indicators and patient outcomes after stroke: An Australian data linkage study
Adherence to ambulance performance indicators and patient outcomes after stroke: An Australian data linkage study Open
EMS adherence to performance indicators improved off-stretcher time and thrombolytic therapy use but was influenced by geographic and socio-economic status. Refining EMS performance targets and tailoring public and EMS education on stroke …
View article: Role of alcohol in urgent ambulance contacts in the Capital Region of Denmark: a 9-year population-based study across sex and age groups
Role of alcohol in urgent ambulance contacts in the Capital Region of Denmark: a 9-year population-based study across sex and age groups Open
Introduction Alcohol consumption is associated with an increased risk of accidents, and previous studies have shown that alcohol-related harm places a significant burden on emergency departments. The aim of this study was to estimate the p…
View article: Incidence and outcomes of out-of-hospital cardiac arrest from initial asystole: a systematic review and meta-analysis
Incidence and outcomes of out-of-hospital cardiac arrest from initial asystole: a systematic review and meta-analysis Open
Initial asystolic OHCA made up 53% of all EMS-treated patients and pooled survival rates were extremely poor. Research efforts in this population should focus on developing prevention strategies as well as adherence to termination or withh…
View article: Patterns of intimate partner violence in Victoria, Australia: analysis using the National Ambulance Surveillance System
Patterns of intimate partner violence in Victoria, Australia: analysis using the National Ambulance Surveillance System Open
Limited surveillance mechanisms have investigated the acute harms associated with intimate partner violence (IPV). This study used novel coded ambulance data to examine the socioeconomic and geographical remoteness distribution of IPV vict…
View article: Costs and Benefits of the Melbourne Mobile Stroke Unit Compared With Standard Ambulance: Causal Analysis Using Observational Linked Data
Costs and Benefits of the Melbourne Mobile Stroke Unit Compared With Standard Ambulance: Causal Analysis Using Observational Linked Data Open
BACKGROUND: Evidence of the cost implications and health outcomes associated with the use of mobile stroke units (MSU) is required to support their utilization. We aimed to evaluate the causal effect of the use of an MSU compared with a st…
View article: Blood culture collection and administration of intravenous ceftriaxone by paramedics in patients with suspected sepsis (the pass trial)
Blood culture collection and administration of intravenous ceftriaxone by paramedics in patients with suspected sepsis (the pass trial) Open
Objective To evaluate the feasibility of pre‐hospital blood culture (BC) collection and intravenous (IV) antibiotic administration in patients with suspected sepsis. Methods In this open‐label trial, BCs were collected in all participants,…
View article: Accelerating Action – Building Purposeful Careers in NDT
Accelerating Action – Building Purposeful Careers in NDT Open
Karen Smith, President of Evident Test & Measurement, has been a leader in the Non-Destructive Testing (NDT) industry for over 37 years. Beginning her career in ultrasound by chance, she quickly developed a passion for the field, progressi…
View article: Opportunities to Digitally Enable Falls Prevention in Older Adults
Opportunities to Digitally Enable Falls Prevention in Older Adults Open
Falls are a serious problem confronting older adults. Evidence demonstrates that multifactorial interventions that target multiple risk factors can reduce falls. However, resource and access constraints impact intervention uptake and susta…
View article: Census 2023: your thoughts, our actions
Census 2023: your thoughts, our actions Open
RCS England's plans to tackle the challenges facing the workforce, increase opportunities for trainees and support future generations of surgeons.
View article: Research themes and key data points for child and adolescent emergency department mental health presentations: A national Delphi study
Research themes and key data points for child and adolescent emergency department mental health presentations: A national Delphi study Open
Objective The objective was to identify a prioritized list of research themes and key data points (baseline data and research outcomes) for future studies regarding child and adolescent emergency department (ED) mental health presentations…
View article: Correction: Identifying areas of Australia with high out-of-hospital cardiac arrest incidence and low bystander cardiopulmonary resuscitation rates: A retrospective, observational study
Correction: Identifying areas of Australia with high out-of-hospital cardiac arrest incidence and low bystander cardiopulmonary resuscitation rates: A retrospective, observational study Open
[This corrects the article DOI: 10.1371/journal.pone.0301176.].
View article: A longitudinal qualitative exploration of Victorian healthcare workers’ and organisations’ evolving views and experiences during COVID-19
A longitudinal qualitative exploration of Victorian healthcare workers’ and organisations’ evolving views and experiences during COVID-19 Open
Background The COVID-19 pandemic has profoundly impacted individuals, society, and healthcare organisations worldwide. Recent international research suggests that concerns, needs, and experiences of healthcare workers (HCWs) have evolved t…
View article: Identifying areas of Australia with high out-of-hospital cardiac arrest incidence and low bystander cardiopulmonary resuscitation rates: A retrospective, observational study
Identifying areas of Australia with high out-of-hospital cardiac arrest incidence and low bystander cardiopulmonary resuscitation rates: A retrospective, observational study Open
Aim This study aims to explore regional variation and identify regions within Australia with high incidence of out-of-hospital cardiac arrest (OHCA) and low rates of bystander cardiopulmonary resuscitation (CPR). Method Adult OHCAs of pres…
View article: Refining ambulance clinical response models: The impact on ambulance response and emergency department presentations
Refining ambulance clinical response models: The impact on ambulance response and emergency department presentations Open
Objective The ambulance service in Victoria, Australia implemented a revised clinical response model (CRM) in 2016 which was designed to increase the diversion of low‐acuity Triple Zero (000) calls to secondary telephone triage and reduce …
View article: Characteristics and Outcomes of Patients Referred to a General Practitioner by Victorian Paramedics
Characteristics and Outcomes of Patients Referred to a General Practitioner by Victorian Paramedics Open
Despite increasing low and medium-acuity casework in this EMS system, paramedic referral to a GP is not common practice. Referring a patient to a GP did not reduce the likelihood of patients experiencing a high acuity outcome or recalling …
View article: Overuse of Computed Tomography Pulmonary Angiography and Low Utilization of Clinical Prediction Rules in Suspected Pulmonary Embolism Patients at a Regional Australian Hospital
Overuse of Computed Tomography Pulmonary Angiography and Low Utilization of Clinical Prediction Rules in Suspected Pulmonary Embolism Patients at a Regional Australian Hospital Open
A pulmonary embolism (PE) is an obstruction in the pulmonary arterial system and may include non-specific signs and symptoms. Clinical prediction rules (CPRs) assess the pretest probability (PTP) of a PE to prevent the overuse of computed …
View article: Rethinking paramedic occupational injury surveillance: A systems approach to better understanding paramedic work-related injury
Rethinking paramedic occupational injury surveillance: A systems approach to better understanding paramedic work-related injury Open
Paramedic work occurs in complex, dynamic, uncontrolled, and unpredictable work environments which increase their risk of occupational injury. The complex and multi-factorial nature of paramedic occupational injury requires a holistic syst…
View article: P453: Double heterozygous variants in ACVRL1 and GDF2 causing hereditary hemorrhagic telangiectasia and GDF2-related vascular anomaly syndrome
P453: Double heterozygous variants in ACVRL1 and GDF2 causing hereditary hemorrhagic telangiectasia and GDF2-related vascular anomaly syndrome Open
Hereditary Hemorrhagic Telangiectasia (HHT), also known as Osler-Weber-Rendu disease, is a variably expressive autosomal dominant vascular disorder characterized by development of mucocutaneous telangiectasias and visceral arteriovenous ma…
View article: The burden and prognostic significance of suspected sepsis in the prehospital setting: A state‐wide population‐based cohort study
The burden and prognostic significance of suspected sepsis in the prehospital setting: A state‐wide population‐based cohort study Open
Objective Despite high in‐hospital mortality, the epidemiology of prehospital suspected sepsis presentations is not well described. This retrospective cohort study aimed to quantify the burden of such presentations, and to determine whethe…
View article: The impact of venous leg ulcers on quality of life
The impact of venous leg ulcers on quality of life Open
Aim To determine the quality of life (QoL) of clients with venous leg ulcers (VLU) treated in the community and investigate if age-related frailty or disability posed an additional impact on QoL.
View article: Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials Open
This synthesis demonstrates that TXA use for trauma in emergencies leads to a reduction in 1-month mortality, with no significant evidence of problematic vascular occlusive events. Administering TXA in the out-of-hospital setting is associ…
View article: Role of alcohol in urgent ambulance contacts in 15-24-year-olds in Copenhagen: a descriptive population-based study
Role of alcohol in urgent ambulance contacts in 15-24-year-olds in Copenhagen: a descriptive population-based study Open
Objective The objective of this study is to estimate the proportion of alcohol-related ambulance contacts and to describe characteristics of these contacts in young people. Design A descriptive population-based study with alcohol-related a…
View article: Sudden cardiac death in people with schizophrenia: higher risk, poorer resuscitation profiles and differing pathologies
Sudden cardiac death in people with schizophrenia: higher risk, poorer resuscitation profiles and differing pathologies Open
Background People with schizophrenia account for approximately 1.0% of the population and appear to experience increased rates of sudden cardiac death (SCD). This study determined characteristics of increased SCD in people with schizophren…
View article: Factors influencing the successful implementation of a novel digital health application to streamline multidisciplinary communication across multiple organisations for emergency care
Factors influencing the successful implementation of a novel digital health application to streamline multidisciplinary communication across multiple organisations for emergency care Open
Rationale Delivering optimal patient health care requires interdisciplinary clinician communication. A single communication tool across multiple pre‐hospital and hospital settings, and between hospital departments is a novel solution to cu…
View article: A study protocol for a cluster-randomised controlled trial of smartphone-activated first responders with ultraportable defibrillators in out-of-hospital cardiac arrest: The First Responder Shock Trial (FIRST)
A study protocol for a cluster-randomised controlled trial of smartphone-activated first responders with ultraportable defibrillators in out-of-hospital cardiac arrest: The First Responder Shock Trial (FIRST) Open
View article: Developing a consensus-based definition of out-of-hospital clinical deterioration: A Delphi study
Developing a consensus-based definition of out-of-hospital clinical deterioration: A Delphi study Open
The creation of a consensus-based definition of OOH clinical deterioration can serve as a starting point for the development and validation of OOH-specific early warning systems. Moreover, a standardised definition allows meaningful compar…
View article: ALFP Debate: Pharmacy Practice Needs Pharmacy Schools to Drive Innovation in the Profession
ALFP Debate: Pharmacy Practice Needs Pharmacy Schools to Drive Innovation in the Profession Open
Objective To describe the pros and cons of the topic "pharmacy practice needs pharmacy schools to drive innovation in the profession." Methods The Academic Leadership Fellows Program (ALFP) contributes to developing leaders in the academy.…
View article: Cura Personalis: Care of the Whole Person Through Student Wellness Initiatives
Cura Personalis: Care of the Whole Person Through Student Wellness Initiatives Open
To strengthen the success of Regis University School of Pharmacy (RUSOP) students through wellness initiatives that incorporate mental, physical, social, and spiritual aspects.
View article: A protocol for the Heart Matters stepped wedge cluster randomised trial: The effectiveness of heart attack education in regions at highest-risk
A protocol for the Heart Matters stepped wedge cluster randomised trial: The effectiveness of heart attack education in regions at highest-risk Open
The results from this trial will provide high-level evidence the effectiveness of a community education intervention targeting regions at highest-risk of ACS and low EMS use.