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View article: Optimizing storage, high-molecular weight DNA extraction and genome reconstructions from human faecal samples
Optimizing storage, high-molecular weight DNA extraction and genome reconstructions from human faecal samples Open
Metagenomic sequencing has become an essential tool for assessing the composition and functional potential of microbial communities. However, established metagenomic DNA extraction protocols are limited by trade-offs between universal taxo…
View article: Genomic evidence of symbiotic adaptations in fungus-associated bacteria
Genomic evidence of symbiotic adaptations in fungus-associated bacteria Open
Fungi harbor diverse bacteria that engage in various relationships. While these relationships potentially influence fungal functioning, their underlying genetic mechanisms remain unexplored. Here, we aimed to elucidate the key genomic feat…
View article: Bisphenol A exposure affects specific gut taxa and drives microbiota dynamics in childhood obesity
Bisphenol A exposure affects specific gut taxa and drives microbiota dynamics in childhood obesity Open
Cumulative xenobiotic exposure has an environmental and human health impact which is currently assessed under the One Health approach. Bisphenol A (BPA) exposure and its potential link with childhood obesity that has parallelly increased d…
View article: Community‐scale models of microbiomes: Articulating metabolic modelling and metagenome sequencing
Community‐scale models of microbiomes: Articulating metabolic modelling and metagenome sequencing Open
Building models is essential for understanding the functions and dynamics of microbial communities. Metabolic models built on genome‐scale metabolic network reconstructions (GENREs) are especially relevant as a means to decipher the comple…
View article: Incorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health
Incorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health Open
Three areas of relevance to the gut microbiome in the context of One Health were explored; the incorporation of the microbiome in food safety risk assessment of xenobiotics; the identification and application of beneficial microbial compon…
View article: Microbiota analysis for risk assessment: evaluation of hazardous dietary substances and its potential role on the gut microbiome variability and dysbiosis
Microbiota analysis for risk assessment: evaluation of hazardous dietary substances and its potential role on the gut microbiome variability and dysbiosis Open
The expansion of fields related to probiotics, microbiome-targeted interventions and an evolving landscape for implementation across policy, industry and end users, signifies an era of important clinical translational changes. Characterist…
View article: OBEMIRISK‐Knowledge platform for assessing the risk of bisphenols on gut microbiota and its role in obesogenic phenotype: looking for biomarkers
OBEMIRISK‐Knowledge platform for assessing the risk of bisphenols on gut microbiota and its role in obesogenic phenotype: looking for biomarkers Open
International audience
View article: Impact of Cumulative Environmental and Dietary Xenobiotics on Human Microbiota: Risk Assessment for One Health
Impact of Cumulative Environmental and Dietary Xenobiotics on Human Microbiota: Risk Assessment for One Health Open
Chemical risk assessment in the context of the risk analysis framework was initially designed to evaluate the impact of hazardous substances or xenobiotics on human health. As the need of multiple stressors assessment was revealed to be mo…
View article: Culturing and Molecular Approaches for Identifying Microbiota Taxa Impacting Children’s Obesogenic Phenotypes Related to Xenobiotic Dietary Exposure
Culturing and Molecular Approaches for Identifying Microbiota Taxa Impacting Children’s Obesogenic Phenotypes Related to Xenobiotic Dietary Exposure Open
Integrated data from molecular and improved culturomics studies might offer holistic insights on gut microbiome dysbiosis triggered by xenobiotics, such as obesity and metabolic disorders. Bisphenol A (BPA), a dietary xenobiotic obesogen, …
View article: Human Gut Microbial Taxa Metabolizing Dietary Obesogens: A BPA 1 directed-culturing and Bioinformatics Combined Approach
Human Gut Microbial Taxa Metabolizing Dietary Obesogens: A BPA 1 directed-culturing and Bioinformatics Combined Approach Open
Background Integrated data from culturomics and functional omics may depict holistic understanding on gut microbiome eubiosis or dysbiosis, and microbial isolates can become a source of differential enzymes and useful bioactive compounds. …
View article: Antimicrobial Effects of Potential Probiotics of Bacillus spp. Isolated from Human Microbiota: In Vitro and In Silico Methods
Antimicrobial Effects of Potential Probiotics of Bacillus spp. Isolated from Human Microbiota: In Vitro and In Silico Methods Open
The variable taxa components of human gut microbiota seem to have an enormous biotechnological potential that is not yet well explored. To investigate the usefulness and applications of its biocompounds and/or bioactive substances would ha…
View article: Next Generation Probiotics for Neutralizing Obesogenic Effects: Taxa Culturing Searching Strategies
Next Generation Probiotics for Neutralizing Obesogenic Effects: Taxa Culturing Searching Strategies Open
The combination of diet, lifestyle, and the exposure to food obesogens categorized into “microbiota disrupting chemicals” (MDC) could determine obesogenic-related dysbiosis and modify the microbiota diversity that impacts on individual hea…