Klara Schmidtke
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View article: Extensive monolayer formation depends on a subpopulation of transplanted human iPSC-derived RPE cells
Extensive monolayer formation depends on a subpopulation of transplanted human iPSC-derived RPE cells Open
Loss of retinal pigment epithelium (RPE) cells in the eye leads to photoreceptor death and vision loss. Cell replacement strategies using RPE derived in vitro from pluripotent stem cells (PSCs) has emerged as a promising therapeutic strate…
View article: Manipulation of the nuclear envelope-associated protein SLAP during mammalian brain development affects cortical lamination and exploratory behavior
Manipulation of the nuclear envelope-associated protein SLAP during mammalian brain development affects cortical lamination and exploratory behavior Open
Here, we report the first characterization of the effects resulting from the manipulation of Soluble-Lamin Associated Protein (SLAP) expression during mammalian brain development. We found that SLAP localizes to the nuclear envelope and wh…
View article: Manipulation of the Nuclear Envelope-Associated Protein SLAP During Mammalian Brain Development Affects Cortical Lamination and Exploratory Behavior
Manipulation of the Nuclear Envelope-Associated Protein SLAP During Mammalian Brain Development Affects Cortical Lamination and Exploratory Behavior Open
Here we report the first characterization of the effects resulting from the manipulation of Soluble-Lamin Associated Protein (SLAP) expression during mammalian brain development. We found that SLAP localizes to the nuclear envelope and whe…
Invited Session II: Retinal remodeling and regeneration: Insights into retinal cell replacement: Optimising photoreceptor and RPE transplantation Open
Retinal degenerative diseases, such as age-related macular degeneration and inherited retinal degenerations, are characterized by the dysfunction and ultimately loss of photoreceptors and retinal pigment epithelium (RPE). Retinal cell repl…