Klaus Mathiak
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View article: Autonomic regulation during cognitive reappraisal in major depressive disorder: a study of fMRI correlates
Autonomic regulation during cognitive reappraisal in major depressive disorder: a study of fMRI correlates Open
Background Emotion regulation mediated by cognitive reappraisal can induce activity changes in brain areas and fluctuations in peripheral physiological indicators regulated by the autonomic nervous system (ANS). However, little is known ab…
View article: Toward navigating emotional states using real-time representational similarity analysis fMRI neurofeedback - a feasibility study
Toward navigating emotional states using real-time representational similarity analysis fMRI neurofeedback - a feasibility study Open
Real-time functional magnetic resonance imaging neurofeedback (rt-fMRI-NF) is a promising non-invasive brain-computer-interface (BCI) technique for enhancing self-regulation of affective states in the brain. However, conventional univariat…
View article: Neural Mechanisms of Feedback Processing and Regulation Recalibration During Neurofeedback Training
Neural Mechanisms of Feedback Processing and Regulation Recalibration During Neurofeedback Training Open
The acquisition of new skills is facilitated by providing individuals with feedback that reflects their performance. This process creates a closed loop that involves feedback processing and regulation recalibration to promote effective tra…
View article: Basic stimulus processing alterations from top-down cognitive control in depression drive independent temporal components of multi-echo naturalistic fMRI data
Basic stimulus processing alterations from top-down cognitive control in depression drive independent temporal components of multi-echo naturalistic fMRI data Open
Perceptual changes in major depressive disorder (MDD) may extend beyond emotional content and include the processing of basic stimulus features. These alterations may ultimately contribute to perceptual bias and anhedonia. To characterize …
View article: Characterizing the distribution of neural and non-neural components in multi-echo EPI data across echo times based on tensor-ICA
Characterizing the distribution of neural and non-neural components in multi-echo EPI data across echo times based on tensor-ICA Open
View article: Unraveling antipsychotic induced weight gain in schizophrenia – A proof-of-concept study exploring the impact of the cumulative historical occupancy of different receptors by antipsychotics
Unraveling antipsychotic induced weight gain in schizophrenia – A proof-of-concept study exploring the impact of the cumulative historical occupancy of different receptors by antipsychotics Open
View article: Specificity of cranial cutaneous manipulations in modulating autonomic nervous system responses and physiological oscillations: A controlled study
Specificity of cranial cutaneous manipulations in modulating autonomic nervous system responses and physiological oscillations: A controlled study Open
Significant autonomic nervous system responses to a specific osteopathic intervention, the cranial vault hold (CVH), have recently been demonstrated in forehead skin blood volume changes, heart rate, and respiration frequencies. The specif…
View article: Physiological fingerprinting of audiovisual warnings in assisted driving conditions: an investigation of fMRI and peripheral physiological indicators
Physiological fingerprinting of audiovisual warnings in assisted driving conditions: an investigation of fMRI and peripheral physiological indicators Open
Physiological responses derived from audiovisual perception during assisted driving are associated with the regulation of the autonomic nervous system (ANS), especially in emergencies. However, the interaction of event-related brain activi…
View article: The Use of Functional Near-Infrared Spectroscopy (fNIRS) for Monitoring Brain Function, Predicting Outcomes, and Evaluating Rehabilitative Interventional Responses in Poststroke Patients with Upper Limb Hemiplegia: A Systematic Review
The Use of Functional Near-Infrared Spectroscopy (fNIRS) for Monitoring Brain Function, Predicting Outcomes, and Evaluating Rehabilitative Interventional Responses in Poststroke Patients with Upper Limb Hemiplegia: A Systematic Review Open
View article: Connectivity‐Based Real‐Time Functional Magnetic Resonance Imaging Neurofeedback in Nicotine Users: Mechanistic and Clinical Effects of Regulating a Meta‐Analytically Defined Target Network in a Double‐Blind Controlled Trial
Connectivity‐Based Real‐Time Functional Magnetic Resonance Imaging Neurofeedback in Nicotine Users: Mechanistic and Clinical Effects of Regulating a Meta‐Analytically Defined Target Network in a Double‐Blind Controlled Trial Open
One of the fundamental questions in real‐time functional magnetic resonance imaging neurofeedback (rt‐fMRI NF) investigations is the definition of a suitable neural target for training. Previously, we applied a meta‐analytical approach to …
View article: Does Unfairness Evoke Anger or Disgust? A Quantitative Neurofunctional Dissection Based on 25 Years of Neuroimaging
Does Unfairness Evoke Anger or Disgust? A Quantitative Neurofunctional Dissection Based on 25 Years of Neuroimaging Open
Over the last decades, the traditional ‘Homo economicus’ model has been increasingly challenged by convergent evidence underscoring the impact of emotions on decision-making. A classic example is the perception of unfairness operationalize…
View article: Neural Mechanisms of Feedback Processing and Regulation Recalibration during Neurofeedback Training
Neural Mechanisms of Feedback Processing and Regulation Recalibration during Neurofeedback Training Open
The acquisition of new skills is facilitated by providing individuals with feedback that reflects their performance. This process creates a closed loop that involves feedback processing and regulation recalibration to promote effective tra…
View article: Spectral changes in electroencephalography linked to neuroactive medications: A computational pipeline for data mining and analysis
Spectral changes in electroencephalography linked to neuroactive medications: A computational pipeline for data mining and analysis Open
The pipeline allows fast testing of different hypotheses regarding links between medications and EEG spectrum through ecological usage of readily available data. It can be utilized to make informed decisions about the design of new clinica…
View article: Motion Artifact Detection for T1-Weighted Brain MR Images Using Convolutional Neural Networks
Motion Artifact Detection for T1-Weighted Brain MR Images Using Convolutional Neural Networks Open
Quality assessment (QA) of magnetic resonance imaging (MRI) encompasses several factors such as noise, contrast, homogeneity, and imaging artifacts. Quality evaluation is often not standardized and relies on the expertise, and vigilance of…
View article: Empathy in schizophrenia: neural alterations during emotion recognition and affective sharing
Empathy in schizophrenia: neural alterations during emotion recognition and affective sharing Open
Introduction Deficits in emotion recognition and processing are characteristic for patients with schizophrenia [SCZ]. Methods We targeted both emotion recognition and affective sharing, one in static and one in dynamic facial stimuli, duri…
View article: Autonomic nervous system responses in the intermediate band to cranial cutaneous stimulation
Autonomic nervous system responses in the intermediate band to cranial cutaneous stimulation Open
Cardiovascular rhythms representing functional states of the autonomic nervous system (ANS) are insufficiently reflected by the current physiological model based on low and high frequency bands (LF, HF, resp.). An intermediate (IM) frequen…
View article: The associations of Positive and Negative Valence Systems, Cognitive Systems and Social Processes on disease severity in anxiety and depressive disorders
The associations of Positive and Negative Valence Systems, Cognitive Systems and Social Processes on disease severity in anxiety and depressive disorders Open
Background Anxiety and depressive disorders share common features of mood dysfunctions. This has stimulated interest in transdiagnostic dimensional research as proposed by the Research Domain Criteria (RDoC) approach by the National Instit…
View article: Validation of subjective manual palpation using objective physiological recordings of the cranial rhythmic impulse during osteopathic manipulative intervention
Validation of subjective manual palpation using objective physiological recordings of the cranial rhythmic impulse during osteopathic manipulative intervention Open
Intermediate (IM) band physiology in skin blood flow exhibits parallels with the primary respiratory mechanism (PRM) or cranial rhythmic impulse (CRI), controversial concepts of osteopathy in the cranial field (OCF). Owing to inconsistent …
View article: Functional connectivity signatures of NMDAR dysfunction in schizophrenia—integrating findings from imaging genetics and pharmaco-fMRI
Functional connectivity signatures of NMDAR dysfunction in schizophrenia—integrating findings from imaging genetics and pharmaco-fMRI Open
View article: Spectral changes in electroencephalography linked to psychiatric medications: a computational pipeline for data mining and analysis (Preprint)
Spectral changes in electroencephalography linked to psychiatric medications: a computational pipeline for data mining and analysis (Preprint) Open
BACKGROUND The increasing amount of open-access medical data provides new opportunities to gain clinically relevant information without recruiting new patients. Even in the absence of the full desired parameter control, this information c…
View article: Editorial: Normalization of human social and emotional dysfunction using noninvasive brain modulation approaches: From proof-of-concept to clinical studies
Editorial: Normalization of human social and emotional dysfunction using noninvasive brain modulation approaches: From proof-of-concept to clinical studies Open
EDITORIAL article Front. Hum. Neurosci., 24 January 2023Sec. Brain Imaging and Stimulation Volume 17 - 2023 | https://doi.org/10.3389/fnhum.2023.1142894
View article: Immediate Autonomic Nervous System Activity in Skin Microcirculation During Osteopathic Cranial Vault Hold Intervention
Immediate Autonomic Nervous System Activity in Skin Microcirculation During Osteopathic Cranial Vault Hold Intervention Open
View article: Spectral Changes in Electroencephalography Linked to Neuroactive Medications: A Computational Pipeline for Data Mining and Analysis
Spectral Changes in Electroencephalography Linked to Neuroactive Medications: A Computational Pipeline for Data Mining and Analysis Open
View article: Immediate autonomic nervous system activity in skin microcirculation during osteopathic cranial vault hold intervention
Immediate autonomic nervous system activity in skin microcirculation during osteopathic cranial vault hold intervention Open
Effects of osteopathy in the cranial field (OCF) frequently involve changes in skin blood flow (SBF) and autonomic nervous system (ANS) functioning. ANS related frequency markers fell short to adequately explain physiological reactions in …
View article: Real-time fMRI neurofeedback compared to cognitive behavioral therapy in a pilot study for the treatment of mild and moderate depression
Real-time fMRI neurofeedback compared to cognitive behavioral therapy in a pilot study for the treatment of mild and moderate depression Open
Real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback was found to reduce depressive symptoms. However, no direct comparison of drug-free patients with an active psychotherapy control group is available. The present study…
View article: Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis
Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis Open
View article: Shared network‐level functional alterations across substance use disorders: A multi‐level kernel density meta‐analysis of resting‐state functional connectivity studies
Shared network‐level functional alterations across substance use disorders: A multi‐level kernel density meta‐analysis of resting‐state functional connectivity studies Open
An increasing number of neuroimaging studies indicate functional alterations in cortico‐striatal loops in individuals with substance use disorders (SUD). Dysregulations in these circuits may contribute to drug‐seeking and drug‐consuming be…
View article: Anxiety and Depression in Adults With Congenital Heart Disease
Anxiety and Depression in Adults With Congenital Heart Disease Open
Introduction Anxiety and depression can worsen outcome in patients with heart disease. We elucidate the prevalence of anxiety and depression in a cohort of adults with congenital heart disease (ACHD). Materials and Methods Prospective scre…
View article: EEG Spectral Changes Linked to Psychiatric Medications: Computational Pipeline for Data Mining and Analysis
EEG Spectral Changes Linked to Psychiatric Medications: Computational Pipeline for Data Mining and Analysis Open
The presented computational pipeline is designed to analyze drug-induced changes in EEG data from the Temple University EEG Corpus. The data is cleaned from artifacts, pre-processed, the averaged absolute and relative frequency powers are …
View article: Validation of subjective manual palpation using objective physiological recordings of the cranial rhythmic impulse during osteopathic manipulative intervention
Validation of subjective manual palpation using objective physiological recordings of the cranial rhythmic impulse during osteopathic manipulative intervention Open
Objective Reticular brain activity described by intermediate (IM) band physiology exhibits parallels to controversial concepts of cranial osteopathy (CO), the primary respiratory mechanism or cranial rhythmic impulse (CRI). Interestingly, …