Klaus Wunderlich
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View article: High-Frequency Basal Cell Carcinoma: Demographic, Clinical, and Histopathological Features in a Belgian Cohort
High-Frequency Basal Cell Carcinoma: Demographic, Clinical, and Histopathological Features in a Belgian Cohort Open
Background: Basal cell carcinoma (BCC) is the most common skin cancer worldwide, with a multifactorial aetiology involving environmental and intrinsic factors. A small subset of patients develops high-frequency BCC (HF-BCC), defined as ≥9 …
View article: Investigating disorder-specific and transdiagnostic alterations in model-based and model-free decision-making
Investigating disorder-specific and transdiagnostic alterations in model-based and model-free decision-making Open
Background Decision-making alterations are present in psychiatric illnesses like major depressive disorder (MDD), obsessive–compulsive disorder (OCD), and schizophrenia, linked to symptoms of the respective disorders. We sought to analyze …
View article: Risk Factors and Innovations in Risk Assessment for Melanoma, Basal Cell Carcinoma, and Squamous Cell Carcinoma
Risk Factors and Innovations in Risk Assessment for Melanoma, Basal Cell Carcinoma, and Squamous Cell Carcinoma Open
Skin cancer is the most frequently diagnosed cancer globally and is preventable. Various risk factors contribute to different types of skin cancer, including melanoma, basal cell carcinoma, and squamous cell carcinoma. These risk factors e…
View article: Investigating disorder-specific and transdiagnostic alterations in model-based and model-free decision-making
Investigating disorder-specific and transdiagnostic alterations in model-based and model-free decision-making Open
Background: Decision-making alterations are present in psychiatric illnesses like major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and schizophrenia, linked to symptoms of the respective disorders. Understanding unique…
View article: Negative symptoms, striatal dopamine and model-free reward decision-making in schizophrenia
Negative symptoms, striatal dopamine and model-free reward decision-making in schizophrenia Open
Negative symptoms, such as lack of motivation or social withdrawal, are highly prevalent and debilitating in patients with schizophrenia. Underlying mechanisms of negative symptoms are incompletely understood, thereby preventing the develo…
View article: S146. ASSOCIATION OF IMPAIRED MODEL-FREE DECISION-MAKING WITH ABERRANT STRIATAL DOPAMINE, BRAIN ACTIVATION, AND COGNITIVE DIFFICULTIES IN PATIENTS WITH SCHIZOPHRENIA DURING PSYCHOTIC REMISSION
S146. ASSOCIATION OF IMPAIRED MODEL-FREE DECISION-MAKING WITH ABERRANT STRIATAL DOPAMINE, BRAIN ACTIVATION, AND COGNITIVE DIFFICULTIES IN PATIENTS WITH SCHIZOPHRENIA DURING PSYCHOTIC REMISSION Open
Background Human decision-making ranges between the extremes of automatic and fast model-free behavior (i.e., relying only on previous outcomes) and more flexible, but computationally demanding model-based behavior (i.e., implementing cogn…