Kohei Tamura
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View article: Numerical study on thermal performance of enhanced geothermal system with CO2 using multistage hydraulic stimulation
Numerical study on thermal performance of enhanced geothermal system with CO2 using multistage hydraulic stimulation Open
A novel collaborative research project aimed at utilizing CO2 to create an artificial geothermal reservoir and extract heat by circulating CO2 was initiated in 2021. In this study, we demonstrated that CO2 may significantly enhance thermal…
View article: Characterization and Identification of Natural Amorphous Rocks Using Infrared, Raman, and Low-Frequency Raman Spectroscopy, Including the Application of Boson Peaks
Characterization and Identification of Natural Amorphous Rocks Using Infrared, Raman, and Low-Frequency Raman Spectroscopy, Including the Application of Boson Peaks Open
In this study, Raman spectra (3700–10 cm –1 ) and attenuated total reflection infrared–far-infrared (ATR-IR/FIR) spectra (4000–50 cm –1 ) including low-frequency region were measured for amorphous rocks, which were five types of obsidians …
View article: Optimizing Timing of Intraperitoneal Chemotherapy to Enhance Intravenous Carboplatin Concentration
Optimizing Timing of Intraperitoneal Chemotherapy to Enhance Intravenous Carboplatin Concentration Open
Despite advances in systemic chemotherapy, patients with gastric cancer (GC) and peritoneal metastases (PMs) continue to have poor prognoses. Intraperitoneal (IP) administration of Paclitaxel (PTX) combined with systemic chemotherapy shows…
View article: Evaluation of CO2 storage and enhanced gas recovery potential in gas shale using kerogen nanopore systems with mesopores and micropores
Evaluation of CO2 storage and enhanced gas recovery potential in gas shale using kerogen nanopore systems with mesopores and micropores Open
With the continuous development of shale gas, CO2 storage in shale gas reservoirs has gained significant attention due to the massive available space in these reservoirs. These shale formations exhibit a complex pore structure with micropo…
View article: The role of non‐genomic actions of progesterone and its membrane receptor agonist in ovarian cancer cell death
The role of non‐genomic actions of progesterone and its membrane receptor agonist in ovarian cancer cell death Open
Background Progesterone therapy is a relatively inexpensive treatment option for endometrial and breast cancers, with few side effects. Two signaling pathways usually mediate the physiological effects of progesterone, namely genomic and no…
View article: Ovarian vein thrombosis after bilateral adnexectomy in a symptomatic patient with concomitant pulmonary embolism: A case report
Ovarian vein thrombosis after bilateral adnexectomy in a symptomatic patient with concomitant pulmonary embolism: A case report Open
This case highlights that OVT, even after adnexectomy, can cause symptoms and PE can occur after this type of OVT. Anticoagulation therapy may be considered in such cases.
View article: Ovarian cancer cell death induced by non-genomic action of progesterone and its receptor agonist via membrane receptors
Ovarian cancer cell death induced by non-genomic action of progesterone and its receptor agonist via membrane receptors Open
Background and Aims: Progesterone therapy is a relatively inexpensive treatment option for endometrial and breast cancers, with few side effects. Two signaling pathways usually mediate the physiological effects of progesterone, namely geno…
View article: Interactions of Hydraulic Fractures With Grain Boundary Discontinuities in the Near Wellbore Region
Interactions of Hydraulic Fractures With Grain Boundary Discontinuities in the Near Wellbore Region Open
Hydraulic fractures often turn or branch, interacting with preexisting discontinuities in the rock mass (e.g., natural fractures or defects). The criteria for fracture penetration or deflection are typically based on the in situ stress, an…
View article: Proceedings of the 65th Annual Meeting of Japan Society of Gynecologic Oncology
Proceedings of the 65th Annual Meeting of Japan Society of Gynecologic Oncology Open
Objective: Human papilloma virus (HPV) infection is the leading cause of cervical cancer.Cervical cancer screening includes Pap test, HPV test, or both; however, uncomfortable sampling process lead to low prevalence rate of screening.There…
View article: Pneumothorax during lenvatinib and pembrolizumab combination therapy for recurrent endometrial cancer: a case report
Pneumothorax during lenvatinib and pembrolizumab combination therapy for recurrent endometrial cancer: a case report Open
obtained model values, there was an observed improvement in both accuracy (97%) and precision (97%).Logistic regression also depicted an enhanced improvement in the classification ability of the model with a 0.97 average weighted score.Con…
View article: Durable response after the discontinuation of pembrolizumab treatment due to an adverse event in a patient with advanced endometrial cancer: A case report
Durable response after the discontinuation of pembrolizumab treatment due to an adverse event in a patient with advanced endometrial cancer: A case report Open
The persistence of antitumor effects has been reported after the completion of treatment with immune checkpoint inhibitors (ICIs) for various types of carcinoma, such as malignant melanoma, exhibiting a durable response. A durable response…
View article: Hydraulic fracture interactions with mineral grains
Hydraulic fracture interactions with mineral grains Open
<p><span>Hydraulic fractures often turn or branch, interacting with pre-existing discontinuities (e.g. natural fracture, grain boundary). Such fracture complexities, especially in the proximity of borehole, impact the subsequen…
View article: Response to and toxicity of weekly paclitaxel and carboplatin in patients with stage IIIC‑IV ovarian cancer and poor general condition
Response to and toxicity of weekly paclitaxel and carboplatin in patients with stage IIIC‑IV ovarian cancer and poor general condition Open
It has remained elusive whether standard chemotherapy regimens are safe for patients with ovarian cancer and poor general condition. The purpose of the present study was to assess the response to and toxicity of weekly paclitaxel and carbo…
View article: Prognostic significance of the number of removed lymph nodes according to FIGO stage in ovarian clear cell carcinoma
Prognostic significance of the number of removed lymph nodes according to FIGO stage in ovarian clear cell carcinoma Open
A previous study by our group reported that removing a larger number of lymph nodes in patients with stage I ovarian clear cell carcinoma (OCCC) improved progression-free survival (PFS). The present study investigated whether clinical cond…
View article: Adsorption, selectivity, and phase behavior in organic nanopores for shale gas and oil development
Adsorption, selectivity, and phase behavior in organic nanopores for shale gas and oil development Open
In a shale gas and oil reservoir, hydrocarbon fluids are stored in organic nanopores with sizes on the order of ∼1–100 nm. The adsorption, selectivity, and phase behavior of hydrocarbons in the nanopores are crucial for estimating the gas-…
View article: Knockout of vasohibin‐2 reduces tubulin carboxypeptidase activity and increases paclitaxel sensitivity in ovarian cancer
Knockout of vasohibin‐2 reduces tubulin carboxypeptidase activity and increases paclitaxel sensitivity in ovarian cancer Open
Vasohibin‐1 (VASH1) is a VEGF‐inducible endothelium‐derived angiogenesis inhibitor, and vasohibin‐2 (VASH2), its homolog, exhibits proangiogenic activity. VASH2 is expressed by various cancer cells and accelerates tumor angiogenesis and pr…
View article: Intrauterine balloon failure: unrecognized placenta accreta spectrum disorders
Intrauterine balloon failure: unrecognized placenta accreta spectrum disorders Open
Several studies indicate that intrauterine balloon (IUB) use is less effective for postpartum hemorrhage (PPH) due to placenta accreta spectrum (PAS) disorders than that due to atonic bleeding. IUB failed to achieve hemostasis because the …
View article: Applications of Vibrational Spectroscopic Techniques to <i>In-situ</i> Analyses
Applications of Vibrational Spectroscopic Techniques to <i>In-situ</i> Analyses Open
赤外（Infrared, IR）分光法やラマン（Raman）分光法といった振動分光学的手法は，これまで定性・定量分析に幅広く用いられているが，分析は専ら据え置き式の装置によって研究室や分析室などのラボレベルで行われてきた．しかし，近年では分析ニーズが多様化し，工場内や屋外といった現場においても試料を高精度に測定できることが求められるようになってきた．著者らはこうしたニーズに応えるべく，据え置き式の装置と同程度の性能を維持しつつも，システムの小型化・ブロック化によって拡張性を…
View article: A Potentially Useful Addition to Predict Spontaneous Resolution of Uterine Artery Pseudoaneurysm: Absence of Diastolic Flow
A Potentially Useful Addition to Predict Spontaneous Resolution of Uterine Artery Pseudoaneurysm: Absence of Diastolic Flow Open
Pregnancy‐associated uterine artery pseudoaneurysm (UAP) usually requires transarterial embolization (TAE) irrespective of the presence/absence of current bleeding. Some UAP cases spontaneously resolve without TAE; however, such UAP is not…