Kohei Tsujino
YOU?
Author Swipe
View article: 10112- ET-10 EVALUATING PBC-IP AS A NOVEL BORON CARRIER IN BNCT
10112- ET-10 EVALUATING PBC-IP AS A NOVEL BORON CARRIER IN BNCT Open
This study aims to expand the application scope of boron neutron capture therapy (BNCT) for BPA-insensitive cancers. To apply BNCT in the treatment of brain tumors, convection-enhanced delivery (CED) is used as the drug administration meth…
View article: AB015. Efficacy and safety of boron neutron capture therapy in managing metastatic spinal tumors: experimental findings
AB015. Efficacy and safety of boron neutron capture therapy in managing metastatic spinal tumors: experimental findings Open
These findings indicate that BNCT may represent a novel therapeutic option in the management of metastatic spinal tumors.
View article: Boron neutron capture therapy delays the decline in neurological function in a mouse model of metastatic spinal tumors
Boron neutron capture therapy delays the decline in neurological function in a mouse model of metastatic spinal tumors Open
Metastatic spinal tumors are increasingly prevalent due to advancements in cancer treatment, leading to prolonged survival rates. This rising prevalence highlights the need for developing more effective therapeutic approaches to address th…
View article: BORON NEUTRON CAPTURE THERAPY USING DIRECT INTRATUMORAL ADMINISTRATION OF A FOLATE RECEPTOR TARGETING NOVEL BORON CARRIER
BORON NEUTRON CAPTURE THERAPY USING DIRECT INTRATUMORAL ADMINISTRATION OF A FOLATE RECEPTOR TARGETING NOVEL BORON CARRIER Open
View article: Translational research of boron neutron capture therapy for spinal cord gliomas using rat model
Translational research of boron neutron capture therapy for spinal cord gliomas using rat model Open
Boron neutron capture therapy (BNCT) is a type of targeted particle radiation therapy with potential applications at the cellular level. Spinal cord gliomas (SCGs) present a substantial challenge owing to their poor prognosis and the lack …
View article: Chordoma Treatment with Boron Neutron Capture Therapy (BNCT): Experimental Insights
Chordoma Treatment with Boron Neutron Capture Therapy (BNCT): Experimental Insights Open
Boron Neutron Capture Therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
View article: Evaluation of the Safety of Folate Receptor-Targeted Boron Carrier in Boron Neutron Capture Therapy (BNCT) for Malignant Gliomas Using CED Administration
Evaluation of the Safety of Folate Receptor-Targeted Boron Carrier in Boron Neutron Capture Therapy (BNCT) for Malignant Gliomas Using CED Administration Open
Knowing how to accumulate boron into the tumor cells is a crucial aspect of boron neutron capture therapy (BNCT), which can be targeted at the cellular level, and the development of novel boron agents other than BPA, which is used in clini…
View article: Exploring BNCT as a Novel Approach for Metastatic Spinal Tumor Management
Exploring BNCT as a Novel Approach for Metastatic Spinal Tumor Management Open
[Background] Boron neutron capture therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
View article: Right-sided Herpes Zoster Ophthalmicus Complicated by Bilateral Third, Fourth, and Sixth Cranial Nerve Palsies and Syndrome of Inappropriate Antidiuretic Hormone Secretion
Right-sided Herpes Zoster Ophthalmicus Complicated by Bilateral Third, Fourth, and Sixth Cranial Nerve Palsies and Syndrome of Inappropriate Antidiuretic Hormone Secretion Open
Cases of herpes zoster ophthalmicus (HZO) complicated by bilateral ophthalmoplegia are rare, and no cases of bilateral third, fourth, or sixth cranial nerve palsies have been reported. Syndrome of inappropriate antidiuretic hormone secreti…
View article: Exploring boron neutron capture therapy as a promising treatment for spinal cord gliomas: in vivo efficacy in rat models
Exploring boron neutron capture therapy as a promising treatment for spinal cord gliomas: in vivo efficacy in rat models Open
Boron neutron capture therapy (BNCT) is a type of targeted particle radiation therapy with potential applications at the cellular level. Spinal cord gliomas (SCGs) present a substantial challenge owing to their poor prognosis and the lack …
View article: Nonclinical pharmacodynamics of boron neutron capture therapy using direct intratumoral administration of a folate receptor targeting novel boron carrier
Nonclinical pharmacodynamics of boron neutron capture therapy using direct intratumoral administration of a folate receptor targeting novel boron carrier Open
Background Boron neutron capture therapy (BNCT) is a precise particle radiation therapy known for its unique cellular targeting ability. The development of innovative boron carriers is crucial for the advancement of BNCT technologies. Our …
View article: 10235-TB-9 TRANSLATIONAL RESEARCH OF BORON NEUTRON CAPTURE THERAPY FOR SPINAL CORD AND SPINE TUMOR IN ANIMAL MODELS
10235-TB-9 TRANSLATIONAL RESEARCH OF BORON NEUTRON CAPTURE THERAPY FOR SPINAL CORD AND SPINE TUMOR IN ANIMAL MODELS Open
BACKGROUND Boron Neutron Capture Therapy (BNCT) is a particle beam therapy that can target at the cellular level. This study evaluated the effectiveness of BNCT on spinal cord gliomas using animal models. METHODS F98 rat glioma or 9L rat g…
View article: Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated closo-Dodecaborate on a Rat Brain Tumor Model
Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated closo-Dodecaborate on a Rat Brain Tumor Model Open
High-grade gliomas present a significant challenge in neuro-oncology because of their aggressive nature and resistance to current therapies. Boron neutron capture therapy (BNCT) is a potential treatment method; however, the boron used by t…
View article: Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated Closo-Dodecaborate on a Rat Brain Tumor Model
Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated Closo-Dodecaborate on a Rat Brain Tumor Model Open
High-grade gliomas present a significant challenge in neuro-oncology because of their aggressive nature and resistance to current therapies. Boron neutron capture therapy (BNCT) is a potential treatment method; however, the boron carrier c…
View article: The efficacy of boron neutron capture therapy with folate receptor targeted novel boron carrier in F98 rat brain tumor models.
The efficacy of boron neutron capture therapy with folate receptor targeted novel boron carrier in F98 rat brain tumor models. Open
21 Background: Boron neutron capture therapy (BNCT) is a particle therapy that can be targeted at the cellular level. The most commonly used boron carrier in clinical BNCT is boronophenylalanine (BPA), which is taken up into the tumor cell…
View article: Improved Boron Neutron Capture Therapy Using Integrin αvβ3-Targeted Long-Retention-Type Boron Carrier in a F98 Rat Glioma Model
Improved Boron Neutron Capture Therapy Using Integrin αvβ3-Targeted Long-Retention-Type Boron Carrier in a F98 Rat Glioma Model Open
Integrin αvβ3 is more highly expressed in high-grade glioma cells than in normal tissues. In this study, a novel boron-10 carrier containing maleimide-functionalized closo-dodecaborate (MID), serum albumin as a drug delivery system, and cy…
View article: ET-4 BASIC RESEARCH OF BORON NEUTRON CAPTURE THERAPY USING A NOVEL BORON COMPOUND TARGETED TO INTEGRIN
ET-4 BASIC RESEARCH OF BORON NEUTRON CAPTURE THERAPY USING A NOVEL BORON COMPOUND TARGETED TO INTEGRIN Open
Background Boron neutron capture therapy (BNCT) is a particle radiation modality capable of selectively destroying tumor cells. The most commonly used boron compound for BNCT is boronphenylalanine (BPA). BPA is taken up into the tumor cell…
View article: RT-6 POTENTIAL AND PROSPECTS OF BORON NEUTRON CAPTURE THERAPY USING A COMBINATION OF MULTIPLE BORON AGENTS
RT-6 POTENTIAL AND PROSPECTS OF BORON NEUTRON CAPTURE THERAPY USING A COMBINATION OF MULTIPLE BORON AGENTS Open
Boron neutron capture therapy (BNCT) is a particle therapy that can target tumors at the cellular level. BNCT has been developed for the treatment of malignant gliomas with widely infiltrated tumors, but as the indication for BNCT was expa…
View article: Boron Compounds for Neutron Capture Therapy in the Treatment of Brain Tumors
Boron Compounds for Neutron Capture Therapy in the Treatment of Brain Tumors Open
Boron neutron capture therapy (BNCT), which uses the capture reaction between neutrons and boron-10, an isotope of boron, is rapidly gaining interest. The reason for this is the successful development of a compact accelerator-type neutron …
View article: Corrigendum: Evaluation of the Effectiveness of the Tap Test by Combining the Use of Functional Gait Assessment and Global Rating of Change
Corrigendum: Evaluation of the Effectiveness of the Tap Test by Combining the Use of Functional Gait Assessment and Global Rating of Change Open
[This corrects the article DOI: 10.3389/fneur.2022.846429.].
View article: Anatomical Limitation of Posterior Spinal Myelotomy for Intramedullary Hemorrhage Associated with Ependymoma or Cavernous Malformation of the High Cervical Spine
Anatomical Limitation of Posterior Spinal Myelotomy for Intramedullary Hemorrhage Associated with Ependymoma or Cavernous Malformation of the High Cervical Spine Open
Spinal intramedullary tumors such as ependymoma or vascular lesions such as cavernous malformation are often at risk of intramedullary hemorrhage. Surgical procedures involving the high cervical spinal cord are often challenging. This tech…
View article: Evaluation of the Effectiveness of the Tap Test by Combining the Use of Functional Gait Assessment and Global Rating of Change
Evaluation of the Effectiveness of the Tap Test by Combining the Use of Functional Gait Assessment and Global Rating of Change Open
Background Although the tap test for patients with suspected idiopathic normal pressure hydrocephalus (iNPH) is still often performed as part of the preoperative evaluation, it is true that some studies have reported the limitations of the…
View article: Bilateral Posterolateral Sulcus Approach for the Removal of Spinal Intramedullary Metastatic Adenocarcinoma: A Technical Case Report
Bilateral Posterolateral Sulcus Approach for the Removal of Spinal Intramedullary Metastatic Adenocarcinoma: A Technical Case Report Open
Spinal intramedullary metastasis is an extremely rare event that occurs in advanced cancer. The surgical indications for spinal intramedullary metastasis are highly limited because of surgical difficulty and poor prognosis. In this technic…