Explanipedia

Optimizing venous outflow reconstruction for V5 & V8 in right-lobe living-donor liver transplantation: “half-circumferential anastomosis” using autologous vein grafts Open

Koichiro Hata, Etsuro Hatano · 2025

The Highest Anti-B Antibody Titer of 8192 in a Patient Undergoing ABO-incompatible Living-donor Liver Transplantation: How to Achieve Donor-specific B-cell Tolerance? Open

Tetsuya Tajima, Koichiro Hata, Shoichi Kageyama, Jiro Kusakabe, Kimiko Yurugi , et al. · 2025

Chronological alterations in de novo malignancies after living‐donor liver transplantation: A cohort study of 1781 recipients using annual comparisons of standardized incidence ratios Open

Tetsuya Tajima, Koichiro Hata, Kosuke Tanaka, Naomi Iyama, Jiro Kusakabe , et al. · 2024

Background De novo malignancies (DNMs) are a major adverse event after solid organ transplantation; however, their characteristics and recent trends after living‐donor liver transplantation (LDLT) remain unclear. Methods We retrospectively…

Venous outflow reconstruction in living‐donor liver transplantation for Budd–Chiari syndrome involving vena cava Open

Koichiro Hata, Takahiro Nishio, Motoyuki Kumagai, Yuki Masano, Shoichi Kageyama , et al. · 2024

Ironically, the hepatic vena cava is mostly involved in Budd‐Chiari syndrome in the Asia‐Pacific region, whereas living‐donor liver transplantation is predominant, which cannot replace the hepatic cava. Hata and colleagues introduced a new…

Delayed, gradual penetration of a fishbone into the pancreas over several months Open

Nobuyuki Tamaki, Koichiro Hata, Kazuhiro Kami · 2024

Present status of PICOLON project Open

K. Fushimi, D. Chernyak, H. Ejiri, Koichiro Hata, R. Hazama , et al. · 2024

The existence of cosmic dark matter and neutrino properties are long-standing problems in cosmology and particle physics. These problems have been investigated by using radiation detectors. We will discuss the application of inorganic crys…

Impact of thoracic shape on the surgical outcomes of laparoscopic‐assisted living donor hepatectomy Open

Kosuke Tanaka, Satoshi Ogiso, Tomoaki Yoh, Ahmed Hussein Abdelhafez, Yuki Masano , et al. · 2023

Background Although laparoscopic‐assisted donor hepatectomy (LADH) has become the definitive procedure for harvesting living donor livers, its surgical outcomes in association with donor body shape have not been elucidated. Methods The imp…

Properdin inhibition ameliorates hepatic ischemia/reperfusion injury without interfering with liver regeneration in mice Open

Jiro Kusakabe, Koichiro Hata, Tetsuya Tajima, Hidetaka Miyauchi, Xiangdong Zhao , et al. · 2023

Hepatic ischemia/reperfusion injury (IRI) often causes serious complications in liver surgeries, including transplantation. Complement activation seems to be involved in hepatic IRI; however, no complement-targeted intervention has been cl…

Anti-complement 5 antibody ameliorates antibody-mediated rejection after liver transplantation in rats Open

Tetsuya Tajima, Koichiro Hata, Jiro Kusakabe, Hidetaka Miyauchi, Joshua Badshah , et al. · 2023

Antibody-mediated rejection (AMR) remains a refractory rejection after donor-specific antibody (DSA)-positive or blood-type incompatible liver transplantation (LT), even in the era of pre-transplant rituximab desensitization. This is due t…

Examination of optimal lymph node dissection for mass-forming type intrahepatic cholangiocarcinoma Open

Makoto Kurimoto, Tomoaki Yoh, Keisuke Okura, Yuichi Takamatsu, Yutaro Hori , et al. · 2023

Makoto KURIMOTO, Tomoaki YOH*, Keisuke OKURA, Yuichi TAKAMATSU, Yutaro HORI, Hiroto NISHINO, Takahiro NISHIO, Yukinori KOYAMA, Satoshi OGISO, Takamichi ISHII, Koichiro HATA, Etsuro HATANO. Ann Hepatobiliary Pancreat Surg 2023;27:S46. https…

Primary hepatic extranodal marginal zone B-cell mucosa-associated lymphoid tissue lymphoma treated by laparoscopic partial hepatectomy: a case report Open

Keisuke Okura, Satoru Seo, Hironori Shimizu, Hiroto Nishino, Tomoaki Yoh , et al. · 2023

Correction: A Conceptual Classification of Resectability for Hepatocellular Carcinoma Open

Tomoaki Yoh, Takamichi Ishii, Takahiro Nishio, Yukinori Koyama, Satoshi Ogiso , et al. · 2022

Antibody production after SARS-CoV2 vaccination and COVID-19 incidence in liver transplant recipients Open

Yuki Masano, Takashi Ito, Hikaru Aoki, Masaaki Hirata, Shinya Okumura , et al. · 2022

Yuki Masano, Takashi Ito, Hikaru Aoki, Masaaki Hirata, Shinya Okumura, Takayuki Anazawa, Kazuyuki Nagai, Koichiro Hata, Etsuro Hatano. Korean J Transplant 2022;36:220. https://doi.org/10.4285/ATW2022.F-3568

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipients with Hepatocellular Carcinoma Open

Gonzalo Sapisochín, Wei‐Chen Lee, Dong Jin Joo, Jae‐Won Joh, Koichiro Hata , et al. · 2022

BACKGROUND The study objective was to evaluate the effect of everolimus (EVR) in combination with reduced tacrolimus (rTAC) compared with a standard TAC (sTAC) regimen on hepatocellular carcinoma (HCC) recurrence in de novo living-donor li…

A Conceptual Classification of Resectability for Hepatocellular Carcinoma Open

Tomoaki Yoh, Takamichi Ishii, Takahiro Nishio, Yukinori Koyama, Satoshi Ogiso , et al. · 2022

Backgrounds In the era of multidisciplinary treatment strategy, resectability for hepatocellular carcinoma (HCC) should be defined. This study aimed to propose and validate a resectability classification of HCC. Methods We proposed followi…

Population pharmacokinetics of everolimus in adult liver transplant patients: Comparison to tacrolimus disposition and extrapolation to pediatrics Open

Kotaro Itohara, Ikuko Yano, Shunsaku Nakagawa, Mitsuhiro Sugimoto, Machiko Hirai , et al. · 2022

Everolimus has recently been used to prevent graft rejection in liver transplantation and reduces the incidence of kidney dysfunction caused by calcineurin inhibitors. In this study, a population pharmacokinetic analysis was conducted to i…

Current status of liver transplantation for <span>non‐B non‐C</span> liver cirrhosis and hepatocellular carcinoma Open

Takahiro Nishio, Takashi Ito, Koichiro Hata, Kojiro Taura, Etsuro Hatano · 2022

Recently, non‐B non‐C chronic liver diseases, including alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH), have markedly increased worldwide. Liver transplantation (LT) is an eff…

Increased expression of programmed cell death ligand 1 and galectin 9 in transplant recipients who achieved tolerance after immunosuppression withdrawal Open

Nguyen Hai Nam, Kojiro Taura, Yukinori Koyama, Takahiro Nishio, Gen Yamamoto , et al. · 2022

COVID-19 Incidence and its Clinical Course in Liver Transplant Recipients Open

Yuki Masano, Takashi Ito, Shinya Okumura, Yukinori Koyama, Takayuki Anazawa , et al. · 2022

Organ transplant recipients receive immunosuppressive drugs and hence are at high risk for COVID-19 due to their compromised immunity.

The impact of human leukocyte antigen mismatch on recipient outcomes in living‐donor liver transplantation Open

Tetsuya Tajima, Koichiro Hata, Jiro Kusakabe, Hidetaka Miyauchi, Kimiko Yurugi , et al. · 2022

Donor-recipient human leukocyte antigen (HLA) compatibility has not been considered to significantly affect liver transplantation (LT) outcomes; however, its significance in living-donor LT (LDLT), which is mostly performed between blood r…

<i>En bloc</i> excision of giant polycystic liver with hepatic cava and its auto‐transplant caval reconstruction as a safe surgical procedure for liver transplantation Open

Koichiro Hata, Takahiro Nishio, Shoichi Kageyama, Satoshi Ogiso, Ken Fukumitsu , et al. · 2022

Safely excising a giant liver while leaving the hepatic inferior vena cava intact is difficult. Hata et al. present images and videos describing their novel technique consisting of total hepatectomy including the hepatic cava; extracorpore…

Impact of neoadjuvant intensity-modulated radiation therapy on borderline resectable pancreatic cancer with arterial abutment; a prospective, open-label, phase II study in a single institution Open

Toshihiko Masui, Kazuyuki Nagai, Takayuki Anazawa, Asahi Sato, Yuichiro Uchida , et al. · 2022

Background Borderline resectable pancreatic cancer (BRPC) is a category of pancreatic cancer that is anatomically widely spread, and curative resection is uncommon with upfront surgery. Intensity-modulated radiation therapy (IMRT) is a for…

Post‐transplant Lymphoproliferative Disorders After Liver Transplantation: A Retrospective Cohort Study Including 1954 Transplants Open

Tetsuya Tajima, Koichiro Hata, Hironori Haga, Momoko Nishikori, Katsutsugu Umeda , et al. · 2021

Post‐transplant lymphoproliferative disorders (PTLDs) are life‐threatening neoplasms after organ transplantation. Because of their rarity and multiple grades of malignancy, the incidence, outcomes, and clinicopathological features affectin…

Preoperative Splenomegaly Is a Risk Factor for Prolonged Splenomegaly after Liver Transplantation and Can Result in Hypersplenism and Graft Fibrosis Open

Kojiro Taura, H N Nguyen, Shiqi Yao, Toshimi Kaido, Yusuke Uemoto , et al. · 2021

Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models Open

Jiro Kusakabe, Koichiro Hata, Hidetaka Miyauchi, Tetsuya Tajima, Yi Wang , et al. · 2021

Cardioprotection via Metabolism for Rat Heart Preservation Using the High-Pressure Gaseous Mixture of Carbon Monoxide and Oxygen Open

Chiharu Suzuki, Naoyuki Hatayama, Tadashi Ogawa, Eri Nanizawa, Shun Otsuka , et al. · 2020

The high-pressure gas (HPG) method with carbon monoxide (CO) and oxygen (O2) mixture maintains the preserved rat heart function. The metabolites of rat hearts preserved using the HPG method (HPG group) and cold storage (CS) method (CS grou…

Middle Hepatic Vein Branch-Guided Approach for Laparoscopic Resection of Liver Segment 8 Is Simple, Reliable, and Reproducible Open

Satoshi Ogiso, Satoru Seo, Takamichi Ishii, Takayuki Anazawa, Kazuyuki Nagai , et al. · 2020

Complement 5 Inhibition Ameliorates Hepatic Ischemia/reperfusion Injury in Mice, Dominantly via the C5a-mediated Cascade Open

Jiro Kusakabe, Koichiro Hata, Ichiro Tamaki, Tetsuya Tajima, Hidetaka Miyauchi , et al. · 2020

Background. Hepatic ischemia/reperfusion injury (IRI) is a serious complication in liver surgeries, including transplantation. Complement activation seems to be closely involved in hepatic IRI; however, no complement-targeted intervention …

Prognostic index consisting of early post‐transplant variables <2 weeks in adult living‐donor liver transplantation Open

Jiro Kusakabe, Koichiro Hata, Shiro Tanaka, Katsuhiro Omae, Yusuke Okamura , et al. · 2020

Aim Six‐month recipient mortality after adult‐to‐adult living‐donor liver transplantation (LDLT) remains high. Early and accurate prediction of recipient outcome and continuous monitoring of recipient severity after surgery are both essent…

The Impact of Biliary Reconstruction Methods on Small Partial Liver Grafts Open

Junichi Yoshikawa, Koichiro Hata, Kojiro Nakamura, Yusuke Okamura, Shinji Üemoto · 2020

Background. Graft recipient weight ratios are lower in adult-to-adult living-donor liver transplantation than in adult-to-adult deceased-donor liver transplantation. Rapid liver regeneration is essential for increased recipient survival ra…

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