Komang Ardi Wahyuningsih
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View article: L-Ascorbic Acid (LAA) Supplementation Enhances Proliferation and Reduces Cellular Senescence in Adipose-Tissue Mesenchymal Stem Cells (AT-MSC) Without Altering Characterization
L-Ascorbic Acid (LAA) Supplementation Enhances Proliferation and Reduces Cellular Senescence in Adipose-Tissue Mesenchymal Stem Cells (AT-MSC) Without Altering Characterization Open
Adipose-tissue mesenchymal stem cells (AT-MSCs) and their secretome have been widely utilized in the field of anti-aging and regenerative medicine. However, the number of AT-MSCs declines during subculture due to cellular senescence. The a…
View article: L-Ascorbic Acid (LAA) Supplementation as a Potential Treatment for Skin Aging: Regulation of Adipose Tissue Mesenchymal Stem Cells (AT-MSCs) Protein Secretion
L-Ascorbic Acid (LAA) Supplementation as a Potential Treatment for Skin Aging: Regulation of Adipose Tissue Mesenchymal Stem Cells (AT-MSCs) Protein Secretion Open
Skin aging is mostly caused by the accumulation of reactive oxygen species (ROS) that lead to cellular dysfunction. One promising therapy for skin aging is the secretome product of adipose tissue mesenchymal stem cells (AT-MSCs). L-ascorbi…
View article: The Combination of Mesenchymal Stem Cell (MSC) Secretome and Vitamin C has a Promising Effect in Treating Skin Aging, as it is Not Significantly Different From Secretome or Vitamin C Alone, Compared to the Untreated Group in a Rat Model of Skin Aging
The Combination of Mesenchymal Stem Cell (MSC) Secretome and Vitamin C has a Promising Effect in Treating Skin Aging, as it is Not Significantly Different From Secretome or Vitamin C Alone, Compared to the Untreated Group in a Rat Model of Skin Aging Open
Skin aging occurs due to gene mutation or hormonal factors called intrinsic factors. Mechanisms of glycation, free radicals, and other cellular and molecular mechanisms can cause dermal atrophy and decreased collagen. The secretome of stem…
View article: L-ascorbic acid (LAA) Supplementation in Adipose-Tissue Mesenchymal Stem Cells (AT-MSC) Culture Induce Proliferation and Prevent Cellular Senescent without Altering Mesenchymal Stem Cells (MSC) Characterization
L-ascorbic acid (LAA) Supplementation in Adipose-Tissue Mesenchymal Stem Cells (AT-MSC) Culture Induce Proliferation and Prevent Cellular Senescent without Altering Mesenchymal Stem Cells (MSC) Characterization Open
Background Adipose-tissue mesenchymal stem cells (AT-MSCs) and its secretome has been used widely in the field of anti-aging and regenerative medicine. However, the number of AT-MSCs decreases during subculture caused by the cell senescenc…
View article: Potential Utilisation of Secretome from Ascorbic Acid-Supplemented Stem Cells in Combating Skin Aging: Systematic Review of A Novel Idea.
Potential Utilisation of Secretome from Ascorbic Acid-Supplemented Stem Cells in Combating Skin Aging: Systematic Review of A Novel Idea. Open
The secretome of stem cells consists of a spectrum of bioactive factors secreted by stem cells grown in culture mediacytokines, chemokines, and growth factors in addition to extracellular vesicles (exosomes and microvesicles). Ease of hand…
View article: The association between vitamin D intake and sleep quality index within the 17-35 year age group
The association between vitamin D intake and sleep quality index within the 17-35 year age group Open
Background : Vitamin D deficiency is a common health problem in the world, even in tropical countries such as Indonesia. The Lack of vitamin D intake from food or supplements can increase the risk of having vitamin D deficiency. The associ…
View article: Perbandingan obesitas general dan obesitas sentral terhadap risiko hipertensi pada usia dewasa di wilayah Kecamatan Cisauk Kabupaten Tangerang
Perbandingan obesitas general dan obesitas sentral terhadap risiko hipertensi pada usia dewasa di wilayah Kecamatan Cisauk Kabupaten Tangerang Open
Pendahuluan: Hipertensi dan obesitas menjadi masalah kesehatan utama hampir diseluruh dunia saat ini. Kejadian hipertensi maupun obesitas meningkat dalam beberapa tahun terakhir. Obesitas telah diketahui sebagai faktor risiko utama terjadi…
View article: The Correlation between Vitamin D Intake and Quality of Life in the 17-35 Age Group
The Correlation between Vitamin D Intake and Quality of Life in the 17-35 Age Group Open
Vitamin D testing increased significantly during the Coronavirus Disease-19 (COVID-19) pandemics due to its role in regulating the immune system. Therefore, vitamin D deficiency is associated with susceptibility to various diseases that ma…
View article: Perbandingan Perubahan Luas Luka dan Angiogenesis pada Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Advanced Platelet-rich Fibrin dan Advanced Platelet-rich Fibrin Plus
Perbandingan Perubahan Luas Luka dan Angiogenesis pada Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Advanced Platelet-rich Fibrin dan Advanced Platelet-rich Fibrin Plus Open
Platelet-rich fibrin (PRF) has a lot of benefits in the process of healing. The new generation of PRF, namely advanced PRF plus (A-PRF+), has a different fibrin structure and more growth factors compared to Advanced PRF (A-PRF), the genera…
View article: Perbandingan Perubahan Luas Luka dan Angiogenesis pada Jaringan Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Platelet Rich Fibrin dan Advanced Platelet Rich Fibrin
Perbandingan Perubahan Luas Luka dan Angiogenesis pada Jaringan Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Platelet Rich Fibrin dan Advanced Platelet Rich Fibrin Open
Burns increase tissue damage by free radicals, thus hindering the healing process. Platelet Rich Fibrin (PRF) and Advanced Platelet Rich Fibrin (A-PRF) are autologous fibrin matrices that contain growth factors and have been proven to incr…
View article: Effect of ascorbic acid on morphology of post-thawed human adipose-derived stem cells
Effect of ascorbic acid on morphology of post-thawed human adipose-derived stem cells Open
These results showed that ascorbic acid increased the cell division and suppressed the aging processes indicated by normal spread cell in size compared to cell cultured in DMFA without ascorbic acid supplementation.
View article: Safety of Technique and Procedure of Stromal Vascular Fraction Therapy: From Liposuction to Cell Administration
Safety of Technique and Procedure of Stromal Vascular Fraction Therapy: From Liposuction to Cell Administration Open
Background . Stromal vascular fraction (SVF) therapy has been performed over the past six years to treat 421 patients by our group in five clinical centers. Autologous SVF, which is a substance containing stem cells, was isolated from lipo…
View article: Biokompatibilitas scaffold sutera asal Bombyx mori ukuran pori 100µm terhadap adipose-derived stem cells (ADSCs) yang dikultur pada berbagai medium pertumbuhan
Biokompatibilitas scaffold sutera asal Bombyx mori ukuran pori 100µm terhadap adipose-derived stem cells (ADSCs) yang dikultur pada berbagai medium pertumbuhan Open
Rekayasa jaringan terdiri dari 3 komponen utama yaitu sel, nutrisi, dan scaffold. Penggunaan sel punca asal jaringan lemak (adipose-derived stem cells/ ADSCs) telah banyak dikembangkan sebagai sumber sel dalam teknologi rekayasa jaringan. …
View article: KONDROGENESIS ADIPOSE-DERIVED STEM CELLS MENGGUNAKAN PLATELET-RICH PLASMA PADA SCAFFOLD SUTRA
KONDROGENESIS ADIPOSE-DERIVED STEM CELLS MENGGUNAKAN PLATELET-RICH PLASMA PADA SCAFFOLD SUTRA Open
AbstrakStudi tentang kemampuan adipose-derived stem cells (ADSCs) sebagai sel punca yang dapat berdiferensiasi menjadi kondrosit menggunakan platelet-rich plasma (PRP) sebagai subtitusi fetal bovine serum (FBS) telah banyak dilaporkan. Pen…
View article: Perbandingan Kemampuan Migrasi Adipose-Derive Stem Cells Asal Manusia pada Berbagai Medium Pertumbuhan
Perbandingan Kemampuan Migrasi Adipose-Derive Stem Cells Asal Manusia pada Berbagai Medium Pertumbuhan Open
Cell migration is natural process that plays an important role in development of organisms. Stem cells are an important in the cells migration process due to repairing tissues or organs. Stem cells ability studies towards cell migration pr…
View article: Evaluation of platelet-rich plasma from diabetic donors shows increased platelet vascular endothelial growth factor release
Evaluation of platelet-rich plasma from diabetic donors shows increased platelet vascular endothelial growth factor release Open
PRP from diabetic donors had higher VEGF content making autologous PRP application a promising treatment for DFU. However, this should be investigated another appropriate clinical trial.
View article: STUDI IN SILICO: PREDIKSI PENGARUH MUTASI TITIK GEN VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 (VEGFR2) TERHADAP STRUKTUR SEKUNDER PROTEIN
STUDI IN SILICO: PREDIKSI PENGARUH MUTASI TITIK GEN VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 (VEGFR2) TERHADAP STRUKTUR SEKUNDER PROTEIN Open
Angiogenesis merupakan proses penting untuk pertumbuhan dan regenerasi sel. Salah satu protein yang berperan dalam angiogenesis adalah vascular endothelial growth factor (VEGF). VEGF akan berinteraksi dengan reseptornya seperti vascular en…
View article: Perbandingan Morfologi Adipose-Derived Stem Cells asal Donor Diabetes Melitus Tipe 2 dalam Medium Mengandung Platelet-Rich Plasma dan Fetal Bovine Serum
Perbandingan Morfologi Adipose-Derived Stem Cells asal Donor Diabetes Melitus Tipe 2 dalam Medium Mengandung Platelet-Rich Plasma dan Fetal Bovine Serum Open
Salah satu terapi luka pada diabetes melitus tipe 2 adalah terapi sel punca. Lingkungan mikro bagi sel termasuk sel punca, dapat rusak akibat komplikasi dari diabetes. Lingkungan mikro yang rusak tersebut dapat menyebabkan penuaan (senesce…