Konstantina Kallinikou
YOU?
Author Swipe
View article: Engraftment defect of cytokine‐cultured adult human mobilized <scp>CD</scp>34<sup>+</sup> cells is related to reduced adhesion to bone marrow niche elements
Engraftment defect of cytokine‐cultured adult human mobilized <span>CD</span>34<sup>+</sup> cells is related to reduced adhesion to bone marrow niche elements Open
Summary In vitro exposure of haematopoietic stem and progenitor cells ( HSPC ) to cytokines in expansion or gene therapy protocols reduces homing and engraftment in vivo . We have previously reported that this is related in part to altered…
View article: Inhibition of cell cycle progression by dual phosphatidylinositol-3-kinase and mTOR blockade in cyclin D2 positive multiple myeloma bearing IgH translocations
Inhibition of cell cycle progression by dual phosphatidylinositol-3-kinase and mTOR blockade in cyclin D2 positive multiple myeloma bearing IgH translocations Open
Multiple myeloma (MM) is a clinically and genetically heterogenous cancer where tumour cells have dysregulated expression of a D-type cyclin, often in association with a recurrent IgH translocation. Patients whose tumour cells express cycl…