Kota Koike
YOU?
Author Swipe
View article: HDAC1 and HDAC2 are bidirectional enzymes that catalyze histone sorbylation to induce epigenetic alterations
HDAC1 and HDAC2 are bidirectional enzymes that catalyze histone sorbylation to induce epigenetic alterations Open
Reversible histone acylation is crucial for epigenetic gene expression regulation. Histone acylation is typically mediated by lysine acyltransferases (KATs), which use acyl-CoAs as acyl donors. Here, we revealed the novel role of the histo…
View article: Lysine long-chain fatty acylation regulates the TEAD transcription factor
Lysine long-chain fatty acylation regulates the TEAD transcription factor Open
TEAD transcription factors are responsible for the transcriptional output of Hippo signaling. TEAD activity is primarily regulated by phosphorylation of its coactivators, YAP and TAZ. In addition, cysteine palmitoylation has recently been …
View article: Simple purification of small-molecule-labelled peptides <i>via</i> palladium enolate formation from β-ketoamide tags
Simple purification of small-molecule-labelled peptides <i>via</i> palladium enolate formation from β-ketoamide tags Open
A solid-supported palladium complex successfully captured β-ketoamide-tagged peptides as palladium enolates and released them in high yield upon acid treatment.
View article: CCDC 1885765: Experimental Crystal Structure Determination
CCDC 1885765: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1885766: Experimental Crystal Structure Determination
CCDC 1885766: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1885767: Experimental Crystal Structure Determination
CCDC 1885767: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1441091: Experimental Crystal Structure Determination
CCDC 1441091: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1441096: Experimental Crystal Structure Determination
CCDC 1441096: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …