Krish Ragunath
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View article: Cannabidiol Is Associated with Improved Survival in Pancreatic Cancer and Modulation of Bile Acids and Gut Microbiota
Cannabidiol Is Associated with Improved Survival in Pancreatic Cancer and Modulation of Bile Acids and Gut Microbiota Open
Pancreatic ductal adenocarcinoma (PDAC) is among the most aggressive malignancies, with dismal survival rates. Cannabinoids have shown anticancer properties in various cancers, including PDAC. This study aimed to evaluate the anticancer ef…
View article: Texture and Color Enhanced Imaging in the Diagnosis of Colonic Neoplasia: A Systematic Review and Analysis
Texture and Color Enhanced Imaging in the Diagnosis of Colonic Neoplasia: A Systematic Review and Analysis Open
Introduction Image enhanced endoscopy (IEE) can augment the detection of colorectal cancer (CRC) and its precursor lesions, potentially reducing incidence and mortality. Early data on texture and color enhancement imaging (TXI) support its…
View article: A pilot evaluation of the artificial intelligence system CAD-EYE to optically characterise lesions in inflammatory bowel disease surveillance
A pilot evaluation of the artificial intelligence system CAD-EYE to optically characterise lesions in inflammatory bowel disease surveillance Open
Background: Patients with inflammatory bowel disease (IBD) have an increased risk of colorectal cancer. Endoscopic surveillance is recommended but is challenging due to the presence of active inflammation, flat dysplasia and inflammatory p…
View article: Cricopharyngeal Per Oral Endoscopic Myotomy (C‐POEM) With a Novel Therapeutic Gastroscope
Cricopharyngeal Per Oral Endoscopic Myotomy (C‐POEM) With a Novel Therapeutic Gastroscope Open
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View article: Three-Dimensional-Printed Gastrointestinal Tract Models for Surgical Planning and Medical Education: A Systematic Review
Three-Dimensional-Printed Gastrointestinal Tract Models for Surgical Planning and Medical Education: A Systematic Review Open
Three-dimensional (3D)-printed models have been extensively applied in operative planning and medical education to directly visualize anatomical structures and gain tactile experiences. Although studies are available on the use of 3D print…
View article: The Promise and Challenges of <scp>CAD</scp>‐Assisted Diagnosis in Achalasia
The Promise and Challenges of <span>CAD</span>‐Assisted Diagnosis in Achalasia Open
View article: Quality Upper Gastrointestinal Endoscopy in Australia and Aotearoa New Zealand: A Joint Position Statement
Quality Upper Gastrointestinal Endoscopy in Australia and Aotearoa New Zealand: A Joint Position Statement Open
Quality standards for upper gastrointestinal (UGI) endoscopy are required to identify key quality indicators that are relevant to Australasian endoscopic practice and local patient populations. Such standards will promote equitable access …
View article: Oncogenic proteome of pancreatic cancer extracellular vesicles: sodium/myo-inositol cotransporter as a potential marker
Oncogenic proteome of pancreatic cancer extracellular vesicles: sodium/myo-inositol cotransporter as a potential marker Open
View article: Three-Dimensional Printed Gastrointestinal Tract Models for Surgical Planning and Medical Education: A Systematic Review
Three-Dimensional Printed Gastrointestinal Tract Models for Surgical Planning and Medical Education: A Systematic Review Open
Three-dimensional (3D)-printed models have been extensively applied in operative planning and medical education to visualize anatomical structures directly and gain a tactile experience. Although studies are available on the use of 3D prin…
View article: International Validation of a Novel PEACE Scale to Improve the Quality of Upper Gastrointestinal Mucosal Inspection During Endoscopy
International Validation of a Novel PEACE Scale to Improve the Quality of Upper Gastrointestinal Mucosal Inspection During Endoscopy Open
INTRODUCTION: The performance of a high quality esophagogastroduodenoscopy (EGD) is dependent on the mucosal cleanliness. Recently, the Polprep: Effective Assessment of Cleanliness in EGD (PEACE) scale was created to assess the degree of m…
View article: Outcomes and validity of risk stratification tools for endoscopic submucosal dissection of early gastric cancer in Western Australia
Outcomes and validity of risk stratification tools for endoscopic submucosal dissection of early gastric cancer in Western Australia Open
Background and Aim Endoscopic submucosal dissection (ESD) has become the treatment of choice for many superficial gastric neoplasms. Clinical outcomes are increasingly comparable between Japanese and Western series; however, data are lacki…
View article: Can optical evaluation distinguish between T1a and T1b esophageal adenocarcinoma: an international expert interobserver agreement study
Can optical evaluation distinguish between T1a and T1b esophageal adenocarcinoma: an international expert interobserver agreement study Open
Background Piecemeal endoscopic mucosal resection (EMR) is an acceptable technique for T1a esophageal adenocarcinoma, but en bloc R0 excision is advocated for T1b disease as it may offer a potential cure and mitigate recurrence. Thus, dist…
View article: Computer-aided diagnosis improves characterization of Barrett’s neoplasia by general endoscopists (with video)
Computer-aided diagnosis improves characterization of Barrett’s neoplasia by general endoscopists (with video) Open
CADx assistance significantly increased characterization performance of BE neoplasia by general endoscopists to the level of expert endoscopists. The use of this CADx system may thereby improve daily Barrett surveillance.
View article: The use of a real-time computer-aided detection system for visible lesions in the Barrett’s esophagus during live endoscopic procedures: a pilot study (with video)
The use of a real-time computer-aided detection system for visible lesions in the Barrett’s esophagus during live endoscopic procedures: a pilot study (with video) Open
In this pilot study, detection by the CADe system of all potentially neoplastic lesions in Barrett's esophagus was comparable to that of an expert endoscopist. Continued refinement of the system may improve specificity. External validation…
View article: Extracellular vesicles in pancreatic cancer: a new era in precision medicine
Extracellular vesicles in pancreatic cancer: a new era in precision medicine Open
Pancreatic cancer (PC) is a lethal disease that presents a considerable challenge to healthcare providers and patients, given its low survival rate. However, recent advancements in precision medicine and innovative technologies have transf…
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No abstract is available for this article.
View article: Hemospray® (Hemostatic powder TC-325) as monotherapy for acute gastrointestinal bleeding: a multi-center prospective study
Hemospray® (Hemostatic powder TC-325) as monotherapy for acute gastrointestinal bleeding: a multi-center prospective study Open
Background Topical hemostatic powders are a reliable second-line approach in acute gastrointestinal (GI) bleeding (AGIB) treatment, according to the existing guidelines. Increasing evidence supports the use of hemostatic powder TC-325 (Hem…
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Severe fi brosis
View article: Hemospray® (hemostatic powder TC-325) as monotherapy for acute gastrointestinal bleeding: a multicenter prospective study
Hemospray® (hemostatic powder TC-325) as monotherapy for acute gastrointestinal bleeding: a multicenter prospective study Open
TC-325 monotherapy is safe and effective, especially in malignancy or post-endoscopic intervention bleeding. In patients with peptic ulcer, it could be helpful when the primary treatment is unfeasible, as bridge to definite therapy.
View article: Adherence to endoscopic surveillance guidelines for patients with inflammatory bowel disease: An Australian cohort study
Adherence to endoscopic surveillance guidelines for patients with inflammatory bowel disease: An Australian cohort study Open
Background and Aim Patients with inflammatory bowel disease have an increased risk of developing colorectal cancer as compared with the general population. Endoscopic surveillance to detect early dysplastic changes is advised by several pu…
View article: A deep learning system for detection of early Barrett's neoplasia: a model development and validation study
A deep learning system for detection of early Barrett's neoplasia: a model development and validation study Open
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Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…
View article: Quality indicators in Barrett's endoscopy: Best is yet to come
Quality indicators in Barrett's endoscopy: Best is yet to come Open
There is growing interest in establishing quality indicators (QIs) for endoscopic screening and surveillance in Barrett's esophagus (BE). QIs are objective, measurable, and evidence‐based metrics that are applicable in a health‐care settin…
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Issue Information Open
Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…
View article: Towards a robust and compact deep learning system for primary detection of early Barrett’s neoplasia: Initial image‐based results of training on a multi‐center retrospectively collected data set
Towards a robust and compact deep learning system for primary detection of early Barrett’s neoplasia: Initial image‐based results of training on a multi‐center retrospectively collected data set Open
Introduction Endoscopic detection of early neoplasia in Barrett's esophagus is difficult. Computer Aided Detection (CADe) systems may assist in neoplasia detection. The aim of this study was to report the first steps in the development of …
View article: Supplementary Figure 2 from DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus
Supplementary Figure 2 from DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus Open
PDF file - 21K,RGN methylation levels in female patient samples
View article: Supplementary Figure 1 from DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus
Supplementary Figure 1 from DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus Open
PDF file - 20K,Internal validation for ATP2B4
View article: Supplementary Figure 1 from DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus
Supplementary Figure 1 from DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus Open
PDF file - 20K,Internal validation for ATP2B4