Explanipedia

Outcomes after Severe AKI Managed Outside ICU in Resource-Constrained Settings: A Prospective Cohort Study Open

Onu Ugochi Chika, Prabhjot Kaur, Nidhi Singh, Raja Ramachandran, Krishan Lal Gupta , et al. · 2024

Recovery from Heart Failure is a Vascular Recovery Open

Rajul Ranka, Krishan Lal Gupta, Felix Naegele, Alexander Lu, Shuang Li , et al. · 2024

Heart failure (HF) remains a major cause of morbidity and mortality worldwide, with limited treatment options. Heart transplantation is an end stage option but limited by donor availability. Left-ventricular assist device (LVAD) implantati…

A randomized trial of once daily versus twice daily dosing of oral iron in CKD Open

Vivek Sood, Kajal Kamboj, Prateek Bhatia, Vishal Sharma, Monica Kundu , et al. · 2023

We investigated the effect of two dosing regimens of oral iron on iron status and hematological parameters in patients with CKD. In this single center, open label, randomized, active controlled clinical trial, stable adult patients with CK…

Atypical Presentation of Acute Mitral Regurgitation Secondary to Papillary Muscle Rupture Open

Kushal H Porwal, Mokshal H. Porwal, Mohammed Mohammed Ibrahim, H. Ramaswamykanive, Krishan Lal Gupta , et al. · 2022

Acute mitral regurgitation (MR) is a life-threatening condition presenting with severe decompensated heart failure due to sudden retrograde blood flow into the left atrium. The causes are broadly classified into ischemic and non-ischemic. …

Intermittent Online Postdilution Hemodiafiltration versus High-Flux Hemodialysis in Non-critical Acute Kidney Injury: A Pilot Randomized Controlled Trial Open

Saurabh Nayak, Arun Prabhahar, Manju J. Chaudhary, Pankaj Bahuguna, Ashok Kumar Yadav , et al. · 2022

The preferential use of convective modes of hemodialysis (HD) for targeting hyper-cytokinemia state in sepsis-related acute kidney injury (AKI) has been questioned for its efficacy. Several studies have used predilution hemodiafiltration (…

Long-Term Follow-Up of Cyclical Cyclophosphamide and Steroids Versus Tacrolimus and Steroids in Primary Membranous Nephropathy Open

Raja Ramachandran, Vinod Kumar, Joyita Bharati, Brad H. Rovin, Ritambhra Nada , et al. · 2021

Decision-making around Commencing Dialysis Open

Indu Ramachandra Rao, Nandini Vallath, YJ Anupama, Krishan Lal Gupta, Krithika Rao · 2021

The decision regarding dialysis initiation is complex. Awareness that renal replacement therapy should not be regarded as default therapy for every patient with advanced renal failure is necessary. Decision to initiate dialysis and modalit…

Proteinuria in Severe Hypothyroidism: A Prospective Study Open

Vijay Singh Gondil, Aarthi Chandrasekaran, Ashu Rastogi, Ashok Kumar Yadav, Ashwani Sood , et al. · 2020

Context Hypothyroidism is associated with reversible decline in kidney function as measured by estimated glomerular filtration rate (eGFR). eGFR and proteinuria are the most important markers for clinical assessment of kidney function. Tho…

Regulatory B and T Cells and Their Association With Clinical Response in New-Onset Lupus Nephritis Patients Open

Niveditha Girimaji, Urvashi Kaundal, Manish Rathi, Aman Sharma, Ritambhra Nada , et al. · 2020

The molecular basis of loss of smell in 2019-nCoV infected individuals Open

Krishan Lal Gupta, Sanjay Kumar Mohanty, Siddhant Kalra, Aayushi Mittal, Tripti Mishra , et al. · 2020

Among the prominent clinical symptoms such as fatigue, shortness of breath, fever, and cough, 2019-nCoV infected individuals often experience hyposmia/anosmia (decrease or loss of sense of smell). Angiotensin I Converting Enzyme 2 (ACE2), …

A Young Female with Fever and Proteinuria Open

Ritambhra Nada, Krishan Lal Gupta, Manish Rathi, Joyita Bharati, M. B. Adarsh · 2020

Aim:We aim to describe an unusual association between systemic lupus erythematosus (SLE) and tuberculosis and the challenges of managing both simultaneously.Background: Systemic lupus erythematosus is an autoimmune disease with an underlyi…

Study of FGF 23 levels in patients with acute kidney injury and its outcome Open

Krishan Lal Gupta, Tirthankar Mohanty, Vivek Sood, Raja Ramachandran · 2020

Membranous nephropathy with collapse: Poor prognosis Open

Joyita Bharati, Archana Sundaram, Navin Pattanashetti, Ritambhra Nada, Vinod Nagesh , et al. · 2019

Poor allograft outcome in Indian patients with post-transplant C3 glomerulopathy Open

Vinod Kumar, Raja Ramachandran, Amit Rawat, Reena Das, Charan Singh Rayat , et al. · 2019

Background Complement 3 glomerulopathy (C3G) results from dysfunction of the alternative complement pathway (ACP). No data are available on post-transplant C3G in South Asia. Methods In this study, renal allograft biopsies of C3G patients …

SP216OUTCOMES OF COMMUNITY ACQUIRED ACUTE KIDNEY INJURY: A PROSPECTIVE COHORT STUDY Open

Krishan Lal Gupta, Vinod Nagesh, Kumar Vivek, Ashok Kumar Yadav · 2019

INTRODUCTION: Acute kidney injury (AKI) is commonly defined using the KDIGO system, which includes criteria based on either rise in serum creatinine (SCr) or fall in urine output (urine volume <0.5 ml/kg/h for 6 hours).The latter has been …

Splenic artery aneurysm in a patient of autosomal dominant polycystic kidney disease: beyond tenuous concomitance! Open

Vivek Sood, Navin Pattanashetti, Krishan Lal Gupta, Raja Ramachandran · 2019

Splenic artery aneurysm (SAA) is rare, with risk of rupture especially if diameter is >2 cm. It is usually asymptomatic and detected incidentally on imaging either in young pregnant women or elderly cirrhotic patients. Extracranial vascula…

Deceptively asymptomatic cryptococcaemia in a renal transplant recipient: the lull before a storm Open

Vivek Sood, Navin Pattanashetti, Raja Ramachandran, Krishan Lal Gupta · 2019

Cryptococcal infection constitutes around 3% of opportunistic infections in solid organ transplant recipients. Most common organ affected in renal transplant recipients (RTRs) is central nervous system and usually presents with chronic men…

Painful neck swelling in a patient with end-stage renal disease on haemodialysis Open

Shabna Sulaiman, Jasmine Sethi, Harbir Singh Kohli, Krishan Lal Gupta · 2019

Acute suppurative thyroiditis (AST) is rarely seen as thyroid gland is highly resistant to infection due its thick capsule and high iodine content.[1][1] Here, we report a case of successfully managed bacterial thyroid abscess in a patient…

032. PREVALENCE OF LACTOFERRIN AND ELASTASE IN NORTH INDIAN COHORT OF ANCA-ASSOCIATED VASCULITIS Open

Ranjana W. Minz, Jagdeep Singh, Aman Sharma, Shashi Anand, Ritambhra Nada , et al. · 2019

Comparison of two steroid regimens in induction therapy of proliferative lupus nephritis: A randomized controlled trial Open

Joyita Bharati, Manish Rathi, Raja Ramachandran, Aman Sharma, Vivek Kumar , et al. · 2019

Opportunistic infections occurring in renal transplant recipients in tropical countries Open

Krishan Lal Gupta, Sahil Bagai, K. Joshi, Manish Rathi, Harbir Singh Kohli , et al. · 2019

Introduction: Renal transplant recipients now have better graft survival rates, but continue to develop opportunistic infections. The present study was aimed at finding the incidence of opportunistic infections in the tropical environment …

The effectiveness of personal hygiene practices on non-cuffed central vein catheter-related infection in patients undergoing hemodialysis: A randomized controlled trial Open

Geetanjali Loomba, Manju Dhandapani, Sukhpal Kaur, Sandhya Ghai, Manisha Biswal , et al. · 2019

Infection of the internal jugular vein (IJV) catheter continues to be a common cause of death in patients with end-stage renal disease undergoing hemodialysis (HD). The present study aimed to evaluate the effectiveness of personal hygiene …

Bilateral renal cortical necrosis in a case of granulomatosis with polyangitis Open

Jasmine Sethi, Ritambhra Nada, Harbir Singh Kohli, Krishan Lal Gupta · 2019

Cincinnati protocol is not suitable for Indian patients with antibody mediated renal allograft rejection Open

Jasmine Sethi, Raja Ramachandran, Vivek Kumar, Manish Rathi, Harbir Singh Kohli , et al. · 2019

Usefulness of mycophenolate mofetil in Indian patients with C3 glomerulopathy Open

Joyita Bharati, Karalanglin Tiewsoh, Vinod Kumar, Ritambhra Nada, Manish Rathi , et al. · 2018

Background C3 glomerulopathy (C3G) is a heterogeneous disease caused by alternative complement pathway abnormalities without any standardized treatment. An immunosuppressive agent, mycophenolate mofetil (MMF), has been recently shown to be…

Postpartum Renal Cortical Necrosis Is Associated With Atypical Hemolytic Uremic Syndrome in Developing Countries Open

Raja Ramachandran, Saurabh Nayak, Hari Prasad Anakutti, Ashok Kumar Yadav, Ritambhra Nada , et al. · 2018

The clinical and laboratory features are highly suggestive of aHUS in more than three-fourths of cases with postpartum RCN. Investigations are needed to look for genetic abnormalities in the complement pathway.

Isolated renal mucormycosis in a patient with Idiopathic CD4 lymphocytopenia Open

Jasmine Sethi, Raja Ramachandran, Harbir Singh Kohli, Krishan Lal Gupta · 2018

Idiopathic CD4 lymphocytopenia (ICL) is characterised by a low CD4 +lymphocyte count in the absence of HIV or other underlying aetiologies. We report a case of a 17-year-old girl with ICL with autoimmune hepatitis who developed isolated re…

Evaluation of Biomarkers: Galactomannan and 1,3-Beta-D-Glucan Assay for the Diagnosis of Invasive Fungal Infections in Immunocompromised Patients from a Tertiary Care Centre Open

Shreya Singh, Harsimran Kaur, Hansraj Choudhary, Shveta Sethi, Pankaj Malhotra , et al. · 2018

BDG has good sensitivity and specificity for distinguishing IFI from no IFIs and GMI may be used for diagnosing IA.

A rare case report of emphysematous cyst infection in autosomal dominant polycystic kidney disease Open

Jasmine Sethi, Raja Ramachandran, Vivek Kumar, Manish Rathi, Harbir Singh Kohli , et al. · 2018

Fever of unknown origin due to primary tubercular splenic abscess in a low-income/middle-income country Open

Jasmine Sethi, Abhinav Shrivastava, Krishan Lal Gupta · 2018

A 49-year-old non-diabetic woman was admitted to our hospital with complaints of fever of unknown origin (FUO) of 2 months’ duration. The patient has no recent history of exposure to tuberculosis (TB). Systemic examination revealed pallor …

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