Krishna Kumar Ganta
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View article: Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha-crystalline beta
Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha-crystalline beta Open
We investigate the magnitude, specificity, and functional properties of Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA-1)-specific antibodies in young adults over the course of primary infection. EBNA-1-specific binding antibodies, as we…
View article: Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha crystalline beta
Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha crystalline beta Open
Epstein-Barr Virus (EBV) infects over 95% of the world’s population and is the most common cause of infectious mononucleosis (IM). Epidemiologic studies have linked EBV with certain cancers or autoimmune conditions, including multiple scle…
View article: Distinct HIV-1 Population Structure across Meningeal and Peripheral T Cells and Macrophage Lineage Cells
Distinct HIV-1 Population Structure across Meningeal and Peripheral T Cells and Macrophage Lineage Cells Open
Different cell types and/or tissues may serve as a reservoir for HIV-1 during ART-induced viral suppression. We compared proviral pol and env sequences from CD3 + T cells and CD14 + macrophage lineage cells from brain and nonbrain tissues …
View article: Expression of Staphylococcal Virulence Genes In Situ in Human Skin and Soft Tissue Infections
Expression of Staphylococcal Virulence Genes In Situ in Human Skin and Soft Tissue Infections Open
Background: Staphylococcus aureus, the most common pathogen in skin and soft tissue infections (SSTI), harbors many well-characterized virulence genes. However, the expression of many of them in SSTIs is unknown. In this study, S. aureus v…
View article: Combinations of siRNAs against La Autoantigen with NS5B or hVAP-A Have Additive Effect on Inhibition of HCV Replication
Combinations of siRNAs against La Autoantigen with NS5B or hVAP-A Have Additive Effect on Inhibition of HCV Replication Open
Hepatitis C virus is major cause of chronic liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Presently available direct-acting antiviral drugs have improved success rate; however, high cost limits th…
View article: Multiple siRNAs against HCV and host genes are more effective in inhibition of HCV replication
Multiple siRNAs against HCV and host genes are more effective in inhibition of HCV replication Open
Background: Hepatitis C virus is a major cause of chronic liver diseases such as chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The present available anti-HCV drugs, Pegylated interferon-α (IFN- α) and Ribavirin have limi…
View article: Multiple siRNAs against HCV and host genes are more effective in inhibition of HCV replication
Multiple siRNAs against HCV and host genes are more effective in inhibition of HCV replication Open