Explanipedia

Salvage Stereotactic Body Radiation Therapy for Locally Recurrent Prostate Cancer: Quality-of-Life Outcomes From a Prospective Clinical Trial Open

Krishnan R. Patel, Erica Schott, Erich P. Huang, Theresa Cooley-Zgela, Holly Ning , et al. · 2025

Evaluating deep learning and radiologist performance in volumetric prostate cancer analysis with biparametric MRI and histopathologically mapped slides Open

Enis C. Yılmaz, Stephanie A. Harmon, Rosina T. Lis, Ömer Tarık Esengür, David G. Gelikman , et al. · 2024

Locoregional Therapies for Hepatocellular Carcinoma Open

Krishnan R. Patel, Hari Menon, Roshal R. Patel, Erich P. Huang, Vivek Verma , et al. · 2024

Importance Several locoregional therapies (LRTs) for nonmetastatic hepatocellular carcinoma (HCC) are available; however, a global comparison of the relative efficacy of each is needed. Objective To conduct a systematic review and direct, …

Challenges and opportunities for early phase clinical trials of novel drug–radiotherapy combinations: recommendations from NRG Oncology, the American Society for Radiation Oncology (ASTRO), the American College of Radiology (ACR), the Sarah Cannon Research Institute, and the American College of Radiation Oncology (ACRO) Open

Zachary S. Zumsteg, Siddharth Sheth, Salma K. Jabbour, Krishnan R. Patel, Randall J. Kimple , et al. · 2024

Target Volume Optimization for Localized Prostate Cancer Open

Krishnan R. Patel, Uulke A. van der Heide, Linda G.W. Kerkmeijer, Ivo G. Schoots, Barış Türkbey , et al. · 2024

Comparative Evaluation of LLMs in Clinical Oncology Open

Nicholas R. Rydzewski, Deepak Dinakaran, Shuang G. Zhao, Eytan Ruppin, Barış Türkbey , et al. · 2024

Of the models tested on a standardized set of oncology questions, GPT-4 was observed to have the highest performance. Although this performance is impressive, all LLMs continue to have clinically significant error rates, including examples…

A platform-independent AI tumor lineage and site (ATLAS) classifier Open

Nicholas R. Rydzewski, Yue Shi, Chenxuan Li, Matthew R. Chrostek, Hamza Bakhtiar , et al. · 2024

Histopathologic diagnosis and classification of cancer plays a critical role in guiding treatment. Advances in next-generation sequencing have ushered in new complementary molecular frameworks. However, existing approaches do not independe…

A Phase 1 Trial of Salvage Stereotactic Body Radiation Therapy for Radiorecurrent Prostate Cancer After Brachytherapy Open

Krishnan R. Patel, Nicholas R. Rydzewski, Erica Schott, Theresa Cooley-Zgela, Holly Ning , et al. · 2024

The MTD of salvage SBRT for the treatment of intraprostatic radiorecurrence after brachytherapy was 42.5 Gy in 5 fractions producing an 86% 2-year biochemical progression-free survival rate, with 1 poststudy failure at 20 months. The most …

A Phase I Trial of Focal Salvage Stereotactic Body Radiation Therapy for Radiorecurrent Prostate Cancer Open

Krishnan R. Patel, Nicholas R. Rydzewski, Erica Schott, Theresa Cooley-Zgela, H. Ning , et al. · 2023

Predicting 18F-DCFPyL-PET/CT Scan Positivity in Prostate Cancer Patients with Biochemical Recurrence Open

K. Lee, Esther Mena, Joanna H. Shih, Liza Lindenberg, Bradford J. Wood , et al. · 2023

Evaluation of a Deep Learning-based Algorithm for Post-Radiotherapy Prostate Cancer Local Recurrence Detection Using Biparametric MRI Open

Enis C. Yılmaz, Stephanie A. Harmon, Mason J. Belue, Katie Merriman, Tim E. Phelps , et al. · 2023

A Phase 1 Trial of Focal Salvage Stereotactic Body Radiation Therapy for Radiorecurrent Prostate Cancer Open

Krishnan R. Patel, Nicholas R. Rydzewski, Erica Schott, Theresa Cooley-Zgela, Holly Ning , et al. · 2023

The MTD for focal salvage SBRT for isolated intraprostatic radiorecurrence was 40 Gy in 5 fractions, producing a 100% 24-month biochemical progression free survival, with 1 poststudy failure at 33 months. The most frequent clinically signi…

Safety of Radiation Therapy in Patients With Prostate Cancer and Inflammatory Bowel Disease: A Systematic Review Open

Matthew Trotta, Krishnan R. Patel, Sarah Singh, Vivek Verma, Jeffrey M. Ryckman · 2023

Postprostatectomy Radiation Therapy in the Setting of a Rectal Vascular Malformation Open

Krishnan R. Patel, Wael E. Saad, Theo Heller, Barış Türkbey, Deborah E. Citrin · 2022

External beam radiation therapy (EBRT) is a potentially curative management option for patients with prostate cancer that recurs after prostatectomy. Although generally well-tolerated, the risk of moderate-to-severe rectal bleeding is an i…

A Phase 1 Trial of Highly Conformal, Hypofractionated Postprostatectomy Radiation Therapy Open

Krishnan R. Patel, Lindsay Rowe, Erica Schott, Theresa Cooley-Zgela, Holly Ning , et al. · 2022

Detection of failure patterns using advanced imaging in patients with biochemical recurrence following low-dose-rate brachytherapy for prostate cancer Open

Kilian Salerno, Barış Türkbey, Liza Lindenberg, Esther Mena, Erica Schott , et al. · 2022

Development of a 3D CNN-based AI Model for Automated Segmentation of the Prostatic Urethra Open

Mason J. Belue, Stephanie A. Harmon, Krishnan R. Patel, Asha Daryanani, Enis C. Yılmaz , et al. · 2022

Detection of Failure Patterns Using Advanced Imaging in Patients With Biochemical Recurrence Following Low Dose Rate Brachytherapy for Prostate Cancer Open

Kilian Salerno, Barış Türkbey, Liza Lindenberg, Esther Mena, Erica Schott , et al. · 2021

Gender & Racial/Ethnic Disparities in Academic Oncology Leadership Open

Gavin Jones, Natasha Dhawan, Akansha Chowdhary, Trevor J. Royce, Krishnan R. Patel , et al. · 2021

A Phase I Trial of Highly Conformal, Hypofractionated Post Prostatectomy Radiotherapy Open

Krishnan R. Patel, Lindsay Rowe, Erica Schott, Theresa Cooley Zgela, H. Ning , et al. · 2021

Tissue-Based Biomarkers for the Risk Stratification of Men With Clinically Localized Prostate Cancer Open

Spyridon P. Basourakos, Michael Tzeng, Patrick Lewicki, Krishnan R. Patel, Bashir Al Hussein Al Awamlh , et al. · 2021

Risk stratification of men with clinically localized prostate cancer has historically relied on basic clinicopathologic parameters such as prostate specific antigen level, grade group, and clinical stage. However, prostate cancer often beh…

Surgical management and lymph-node biopsy of rare malignant cutaneous adnexal carcinomas: a population-based analysis of 7591 patients Open

Amrita Goyal, Theodore Marghitu, Nikhil Goyal, Nathan Rubin, Krishnan R. Patel , et al. · 2020

Mycosis fungoides: developments in incidence, treatment and survival Open

A. Kaufman, Krishnan R. Patel, Kavita Goyal, Daniel E. O’Leary, Nathan Rubin , et al. · 2020

Background Prior studies have demonstrated improved disease‐specific survival of mycosis fungoides (MF) patients over the last 50 years. Objective To analyse patterns of survival and incidence from 1973 to 2016 and determine whether appare…

EP-1586: Docetaxel – Mitigating the high price of success Open

Yi-Bing Song, S. Morrison, Jeri‐Anne Lyons, Krishnan R. Patel, Catherine Coyle , et al. · 2018

Evaluating engrailed-2 and cytokines in urine with serum PSA as potential biomarkers in patients with prostatism at Moi Teaching and Referral Hospital, Eldoret, Kenya Open

B Donald-Buri, Krishnan R. Patel, P Musau, Eleanor N. Fish · 2016

Background: Prostatism is a clinical syndrome, occurring mostly in older men, usually caused by enlargement of the prostate gland and manifested by irritative and obstructive symptoms. Prostate cancer (CaP) is the most common non-cutaneous…

A Nationwide Medical Student Assessment of Oncology Education Open

Malcolm D. Mattes, Krishnan R. Patel, Lindsay Burt, Ariel E. Hirsch · 2015

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