Kristel Van Calsteren
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View article: Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Figures 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Supplmeentary Figures S1-S28
View article: Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features
Supplementary Tables 1 from Poor Outcome in Postpartum Breast Cancer Patients Is Associated with Distinct Molecular and Immunologic Features Open
Table S1 - Table S4
View article: Hearing assesment in children after intrauterine exposure to platinum-based treatment of pregnant cancer patients: A study from the International Network on Cancer, Infertility and Pregnancy
Hearing assesment in children after intrauterine exposure to platinum-based treatment of pregnant cancer patients: A study from the International Network on Cancer, Infertility and Pregnancy Open
View article: Vulvar and vaginal cancer during pregnancy: A pooled analysis of 15 cases from the International Network on Cancer, Infertility and Pregnancy and review of the literature
Vulvar and vaginal cancer during pregnancy: A pooled analysis of 15 cases from the International Network on Cancer, Infertility and Pregnancy and review of the literature Open
Introduction Vulvovaginal cancer in pregnancy is rare. Limited data complicate decision‐making and patient counseling. Our review, coupled with new case data, fills a current gap in the literature and provides practical insights. Material …
View article: Long-term development of 12- and 15-year-old offspring after maternal cancer diagnosis during pregnancy: a prospective multicentre cohort study
Long-term development of 12- and 15-year-old offspring after maternal cancer diagnosis during pregnancy: a prospective multicentre cohort study Open
View article: Figure S2 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Figure S2 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
Figure S2 showing DBS and indel count in the cord blood DNA.
View article: Tables S1-3 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Tables S1-3 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
Supplementary tables listing demographic, oncological and obstetrical data per patient (Table S1), statistical comparisons (Table S2) and annotated variants (Table S3).
View article: Figure S5 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Figure S5 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
Figure S5 showing a comparison between the in vitro generated mutational signatures and the COSMIC database.
View article: Figure S1 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Figure S1 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
FigureS1 showing the assessment of possible maternal contamination in the cord blood samples.
View article: Figure S3 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Figure S3 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
Figure S3 showing a comparison between identified mutational signatures from the samples and the COSMIC database.
View article: Data from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Data from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
Chemotherapy is included in the standard-of-care for cancer treatment during pregnancy. However, whether prenatal exposure to maternal chemotherapy treatment has a mutagenic impact on the fetal genome remains unexplored. Therefore, we inve…
View article: Figure S4 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Figure S4 from Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
Figure S4 showing the identified indel signatures in the cord blood samples.
View article: The Development of a Multidisciplinary Care Pathway for Patients with Inflammatory Bowel Disease Before, During and After Pregnancy
The Development of a Multidisciplinary Care Pathway for Patients with Inflammatory Bowel Disease Before, During and After Pregnancy Open
Background/Objectives: Recent advancements have significantly enhanced our understanding of the interplay between inflammatory bowel disease (IBD) and reproductive health. While international organizations provide guidelines for best pract…
View article: Persistent Uninterpretable or Failed Prenatal Cell‐Free DNA Screening Indicates a High‐Risk Pregnancy and is Associated With Biological Factors Interfering With cfDNA‐Analysis: A Prospective Cohort Study
Persistent Uninterpretable or Failed Prenatal Cell‐Free DNA Screening Indicates a High‐Risk Pregnancy and is Associated With Biological Factors Interfering With cfDNA‐Analysis: A Prospective Cohort Study Open
Objective To investigate maternal characteristics, underlying factors and perinatal outcome in pregnancies with persistent uninterpretable prenatal cfDNA screening in a general obstetric population (GOP). Methods This study included pregna…
View article: 162MO Long-term development of 12- and 15-year-old offspring after maternal cancer during pregnancy: A prospective multicentre cohort study
162MO Long-term development of 12- and 15-year-old offspring after maternal cancer during pregnancy: A prospective multicentre cohort study Open
View article: Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells Open
Chemotherapy is included in the standard-of-care for cancer treatment during pregnancy. However, whether prenatal exposure to maternal chemotherapy treatment has a mutagenic impact on the fetal genome remains unexplored. Therefore, we inve…
View article: Alcohol, Tobacco and Illicit Drug Use During Pregnancy in the Longitudinal BELpREG Cohort in Belgium Between 2022 and 2024
Alcohol, Tobacco and Illicit Drug Use During Pregnancy in the Longitudinal BELpREG Cohort in Belgium Between 2022 and 2024 Open
Background/Objectives: Substance use during pregnancy is associated with adverse outcomes for both mother and child. This study aimed to determine the prevalence and determinants of alcohol, tobacco and illicit drug use before and during p…
View article: Child outcomes after prenatal exposure to platinum and taxane-based chemotherapy: an unplanned interim analysis of the international network on cancer, infertility, and pregnancy study
Child outcomes after prenatal exposure to platinum and taxane-based chemotherapy: an unplanned interim analysis of the international network on cancer, infertility, and pregnancy study Open
View article: Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Table S1 - Table S4
View article: Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Supplmeentary Figures S1-S28
View article: Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Tables 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Table S1 - Table S4
View article: Data from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Data from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Purpose: Postpartum breast cancer patients diagnosed after cessation of breastfeeding (post-weaning, PP-BCPW), have a particularly poor prognosis compared to patients diagnosed during lactation (PP-BCDL), or to pregna…
View article: Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features
Supplementary Figures 1 from Poor outcome in postpartum breast cancer patients is associated with distinct molecular and immunological features Open
Supplmeentary Figures S1-S28
View article: 47 Determining the concentration of maternal medicines in human milk: the UmbrelLACT study protocol
47 Determining the concentration of maternal medicines in human milk: the UmbrelLACT study protocol Open
Introduction An extensive information gap regarding safety of medicines during lactation still exists today. At least 50% of women need pharmacotherapy in the postpartum period and the proportion of breastfeeding women needing medication i…
View article: Interventional radiology for prevention and management of postpartum haemorrhage: a single centre retrospective cohort study
Interventional radiology for prevention and management of postpartum haemorrhage: a single centre retrospective cohort study Open
Purpose Postpartum haemorrhage (PPH) remains a leading cause of maternal death despite current medical management. Surgical interventions are still needed for refractory bleeding. Interventional radiology (IR) can be a successful intermedi…
View article: Urogenital cultures and preterm birth in women with cervical cerclage: a single center retrospective cohort study
Urogenital cultures and preterm birth in women with cervical cerclage: a single center retrospective cohort study Open
View article: Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol—a contribution from the ConcePTION project
Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol—a contribution from the ConcePTION project Open
Introduction Breastfeeding is beneficial for the health of the mother and child. However, at least 50% of postpartum women need pharmacotherapy, and this number is rising due to the increasing prevalence of chronic diseases and pregnancies…
View article: Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology
Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology Open
Circulating cell-free DNA (cfDNA) fragments have characteristics that are specific to the cell types that release them. Current methods for cfDNA deconvolution typically use disease tailored marker selection in a limited number of bulk tis…
View article: Evaluating offspring Genomic and Epigenomic alterations after prenatal exposure to Cancer treatment In Pregnancy (GE-CIP): a multicentric observational study
Evaluating offspring Genomic and Epigenomic alterations after prenatal exposure to Cancer treatment In Pregnancy (GE-CIP): a multicentric observational study Open
Introduction Around 1 in 1000–2000 pregnancies are affected by a cancer diagnosis. Previous studies have shown that chemotherapy during pregnancy has reassuring cognitive and cardiac neonatal outcomes, and hence has been proposed as standa…
View article: Reassuring pregnancy outcomes in women with mild COL4A3-5–related disease (Alport syndrome) and genetic type of disease can aid personalized counseling
Reassuring pregnancy outcomes in women with mild COL4A3-5–related disease (Alport syndrome) and genetic type of disease can aid personalized counseling Open