Ken Robertson
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View article: Elevated body temperature exacerbates arrhythmia and seizure-like activity in a zebrafish model of Timothy syndrome
Elevated body temperature exacerbates arrhythmia and seizure-like activity in a zebrafish model of Timothy syndrome Open
Timothy syndrome (TS) is a multisystem disorder with autistic-like features, seizures and arrhythmia as the main symptoms. Most TS cases are caused by a de novo single amino acid substitution G406R in the CACNA1C gene that encodes the pore…
View article: Assessment of safety through mutagenicity and subchronic toxicity studies with black pepper extract preparation
Assessment of safety through mutagenicity and subchronic toxicity studies with black pepper extract preparation Open
Introduction Black pepper ( Piper nigrum) is a rich source of natural and bioactive components such as N-trans-feruloyltyramine (NFT). In this paper, we discuss the results of the subchronic toxicity and mutagenicity studies conducted to u…
View article: Lipoprotein Metabolism in APOB L343V Familial Hypobetalipoproteinemia
Lipoprotein Metabolism in APOB L343V Familial Hypobetalipoproteinemia Open
Context: Familial hypobetalipoproteinemia (FHBL) is a codominant disorder of lipoprotein metabolism characterized by decreased plasma concentrations of low-density lipoprotein (LDL)-cholesterol and apolipoprotein B (apoB). Objective: The o…