Kristin Wucherer
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View article: Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms
Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms Open
View article: Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP
Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP Open
Microtubule-associated protein tau (MAPT/tau) accumulates in a family of neurodegenerative diseases, including Alzheimer’s disease (AD). In disease, tau is aberrantly modified by post-translational modifications (PTMs), including hyper-pho…
View article: Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP
Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP Open
Microtubule-associated protein tau (MAPT/tau) accumulates in a family of neurodegenerative diseases, including Alzheimer’s disease (AD). In disease, tau is aberrantly modified by post-translational modifications (PTMs), including hyper-pho…
View article: Abstract 1654: ORF28 of HHV-8 interacts with the E3 CHIP to mediate the ubiquitination of host membrane proteins
Abstract 1654: ORF28 of HHV-8 interacts with the E3 CHIP to mediate the ubiquitination of host membrane proteins Open
View article: Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine Open
Viruses are responsible for some of the most deadly human diseases, yet available vaccines and antivirals address only a fraction of the potential viral human pathogens. Here, we provide a methodology for managing human herpesvirus (HHV) i…