Kristine E. Ensrud
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View article: Association of Objective Long Sleep Duration and Insomnia with Objective Short Sleep Duration Phenotypes with Mortality in Older Persons
Association of Objective Long Sleep Duration and Insomnia with Objective Short Sleep Duration Phenotypes with Mortality in Older Persons Open
Objective To investigate the association of objective long sleep duration (LS) and insomnia with objective short sleep duration (ISSD) with mortality in older persons. Methods In 3,054 men (average age 76.4±5.5; mean follow-up=12.1 years) …
View article: OR23-07 Association of Insulin-Resistance and Fracture Risk in the MrOS cohort
OR23-07 Association of Insulin-Resistance and Fracture Risk in the MrOS cohort Open
Disclosure: J. Ha: None. L. Lui: None. K.E. Ensrud: None. Q. Xiao: None. A.R. Hoffman: None. J.Y. Wu: None. Background: Insulin resistance (IR) is closely associated with chronic conditions such as type 2 diabetes and hypertension (1). How…
View article: An international multi-cohort investigation of self-reported sleep and future depressive symptoms in older adults
An international multi-cohort investigation of self-reported sleep and future depressive symptoms in older adults Open
Poor subjective sleep is associated with future depression in older adults, but there is limited consensus on which sleep features have the strongest associations. Moreover, composite scores incorporating multiple features may better repre…
View article: Performance-based physical functioning and incident IADL limitations in a cohort of community-dwelling older women
Performance-based physical functioning and incident IADL limitations in a cohort of community-dwelling older women Open
Background Limitations in activities of daily living have widespread implications for the well-being of older adults. However, the relation between performance-based physical function and self-reported functional impairment is inconsistent…
View article: Race, Ethnicity, and Mortality Following Major Osteoporotic Fracture: Results from the Women’s Health Initiative Study
Race, Ethnicity, and Mortality Following Major Osteoporotic Fracture: Results from the Women’s Health Initiative Study Open
Background Major osteoporotic fracture (MOF) is associated with increased mortality; however, few studies in postmenopausal women have examined racial and ethnic differences in 1-year and 5-year mortality following MOF. Objective To assess…
View article: Change in D3Cr muscle mass in oldest old men and its association with changes in grip strength and walking speed
Change in D3Cr muscle mass in oldest old men and its association with changes in grip strength and walking speed Open
Background The use of lean soft tissue (LST) mass as a surrogate measurement of skeletal muscle mass (SMM) has led to the conclusion that muscle loss is poorly related to functional decline. We hypothesized that when using a more accurate …
View article: Identifying Younger Postmenopausal Women With Osteoporosis Using USPSTF-Recommended Osteoporosis Risk Assessment Tools
Identifying Younger Postmenopausal Women With Osteoporosis Using USPSTF-Recommended Osteoporosis Risk Assessment Tools Open
Importance For younger postmenopausal women, clinical guidelines recommend using osteoporosis risk prediction tools to identify candidates with low bone mineral density (BMD). However, the performance of these tools is not well quantified.…
View article: Difference in Cystatin C-Based and Creatinine-Based eGFR and Cognition in Osteoporotic Fracture in Men Study
Difference in Cystatin C-Based and Creatinine-Based eGFR and Cognition in Osteoporotic Fracture in Men Study Open
View article: Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study
Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study Open
View article: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study
Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study Open
View article: Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study
Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study Open
View article: Circumstances of clinical fracture events with advancing age in older men
Circumstances of clinical fracture events with advancing age in older men Open
To characterize fracture circumstances by age at time of fracture among community-dwelling older men, we analyzed incident clinical fractures in the Osteoporotic Fractures in Men study. Participants were contacted every 4 mo to identify fr…
View article: Back pain precedes sleep problems in older men
Back pain precedes sleep problems in older men Open
Background and Objectives While cross-sectional associations between any pain and sleep problems have been established, longitudinal studies examining the temporal relationship between back pain and multidimensional sleep health remain lim…
View article: EFFECTS OF FRAILTY AND FUNCTIONAL IMPAIRMENT ON THE ASSOCIATIONS OF COGNITIVE IMPAIRMENT AND DEMENTIA WITH HEALTHCARE COSTS
EFFECTS OF FRAILTY AND FUNCTIONAL IMPAIRMENT ON THE ASSOCIATIONS OF COGNITIVE IMPAIRMENT AND DEMENTIA WITH HEALTHCARE COSTS Open
Dementia and cognitive impairment (DCI) are associated with higher total healthcare costs (THC). We sought to determine the fraction of incremental THC of DCI accounted for by frailty and/or functional impairment. We utilized a multi-cohor…
View article: NOVEL METHODS, MODELS, AND METRICS FOR MEDICARE DATA TO UNDERSTAND RECOVERY AFTER HOSPITALIZATION FOR INJURY
NOVEL METHODS, MODELS, AND METRICS FOR MEDICARE DATA TO UNDERSTAND RECOVERY AFTER HOSPITALIZATION FOR INJURY Open
Medicare is the U.S. federal health insurance program for adults aged ≥65 years and some younger persons with specific conditions. The Medicare Minimum Data Set (MDS) is a standardized clinical assessment tool administered by the Centers f…
View article: INCREMENTAL HEALTH CARE COSTS OF A SIMPLE MEASURE OF PHENOTYPIC FRAILTY IN OLDER ADULTS
INCREMENTAL HEALTH CARE COSTS OF A SIMPLE MEASURE OF PHENOTYPIC FRAILTY IN OLDER ADULTS Open
Frailty defined by the CHS phenotype is associated with higher subsequent total healthcare expenditures in community-dwelling Medicare beneficiaries after accounting for claims-based cost indicators. However, frailty assessment using the 5…
View article: Incremental healthcare costs of the simple <scp>SOF</scp> measure of phenotypic frailty in community‐dwelling older adults
Incremental healthcare costs of the simple <span>SOF</span> measure of phenotypic frailty in community‐dwelling older adults Open
Background Frailty defined by the Cardiovascular Health Study (CHS) phenotype is associated with higher healthcare expenditures in community‐dwelling Medicare beneficiaries after accounting for claims‐based cost indicators. However, frailt…
View article: Life‐space mobility and cognition in community‐dwelling late‐life women: A cross‐sectional analysis
Life‐space mobility and cognition in community‐dwelling late‐life women: A cross‐sectional analysis Open
Background Life‐space mobility captures the daily, enacted mobility of older adults. We determined cross‐sectional associations between life‐space mobility and cognitive impairment (CI) among community‐dwelling women in the 9th and 10th de…
View article: Complementary and Alternative Therapies for Genitourinary Syndrome of Menopause
Complementary and Alternative Therapies for Genitourinary Syndrome of Menopause Open
Agency for Healthcare Research and Quality and Patient-Centered Outcomes Research Institute. (PROSPERO: CRD42023400684).
View article: Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause
Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause Open
Agency for Healthcare Research and Quality and Patient-Centered Outcomes Research Institute. (PROSPERO: CRD42023400684).
View article: Fall Trajectories in Older Men: Trajectories of Change by Age and Predictors for Future Fall Risk
Fall Trajectories in Older Men: Trajectories of Change by Age and Predictors for Future Fall Risk Open
Background Very little is known about specific trajectories or patterns of falls over time. Using the well-characterized cohort of the Osteoporotic Fractures in Men Study (MrOS), we classified individuals by fall trajectories across age an…
View article: Long-term Trajectories of Low Back Pain in Older Men: A Prospective Cohort Study With 10-Year Analysis of the Osteoporotic Fractures in Men Study
Long-term Trajectories of Low Back Pain in Older Men: A Prospective Cohort Study With 10-Year Analysis of the Osteoporotic Fractures in Men Study Open
Although low back pain (LBP) may persist or recur over time, few studies have evaluated the individual course of LBP over a long-term period, particularly among older adults. Based on data from the longitudinal Osteoporotic Fractures in Me…
View article: Hip Fracture Risk Assessment Tools for Adults Aged 80 Years and Older
Hip Fracture Risk Assessment Tools for Adults Aged 80 Years and Older Open
Importance While adults aged 80 years and older account for 70% of hip fractures in the US, performance of fracture risk assessment tools in this population is uncertain. Objective To compare performance of the Fracture Risk Assessment Too…
View article: Predictive value of sarcopenia components for all-cause mortality: findings from population-based cohorts
Predictive value of sarcopenia components for all-cause mortality: findings from population-based cohorts Open
Background Low grip strength and gait speed are associated with mortality. However, investigation of the additional mortality risk explained by these measures, over and above other factors, is limited. Aim We examined whether grip strength…
View article: Difference between kidney function by cystatin C versus creatinine and association with muscle mass and frailty
Difference between kidney function by cystatin C versus creatinine and association with muscle mass and frailty Open
Background A higher difference in estimated glomerular filtration rate by cystatin C versus creatinine (eGFRDiff = eGFRCys – eGFRCreat) is associated with decreased frailty risk. Since eGFRCreat is influenced by muscle more than eGFRCys, m…
View article: Associations of empirically derived dietary patterns and cognitive performance in older men: Results of the Osteoporotic Fractures in Men (MrOS) study
Associations of empirically derived dietary patterns and cognitive performance in older men: Results of the Osteoporotic Fractures in Men (MrOS) study Open
The results do not support a robust protective effect of the Prudent dietary pattern on cognition in the MrOS cohort. Associations between the Western dietary pattern and better cognitive scores should be interpreted with caution. Further …
View article: Association of back pain with all-cause and cause-specific mortality among older men: a cohort study
Association of back pain with all-cause and cause-specific mortality among older men: a cohort study Open
Objective We evaluated whether more severe back pain phenotypes—persistent, frequent, or disabling back pain—are associated with higher mortality rate among older men. Methods In this secondary analysis of a prospective cohort, the Osteopo…
View article: Physical function trajectory after wrist or lower arm fracture in postmenopausal women: results from the Women’s Health Initiative Study
Physical function trajectory after wrist or lower arm fracture in postmenopausal women: results from the Women’s Health Initiative Study Open
View article: Balancing fracture risk versus risk of mortality before fracture among women aged 80 years or older
Balancing fracture risk versus risk of mortality before fracture among women aged 80 years or older Open
Background Most fractures occur in women aged ≥80 years but competing mortality unrelated to fracture may limit the benefit of osteoporosis drug therapy for some women in late life. Our primary aim was to develop separate prediction models…
View article: An Internatioanl Multi-Cohort Investigation of Self-Report Sleep and Future Depressive Symptoms in Older Adults
An Internatioanl Multi-Cohort Investigation of Self-Report Sleep and Future Depressive Symptoms in Older Adults Open