Kristofer Jennings
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View article: The impact of a web-based prognostic calculator on prognostic confidence in outpatient palliative care
The impact of a web-based prognostic calculator on prognostic confidence in outpatient palliative care Open
View article: Multiparametric <scp>MRI</scp> Scoring System of the Pancreas for the Diagnosis of Chronic Pancreatitis
Multiparametric <span>MRI</span> Scoring System of the Pancreas for the Diagnosis of Chronic Pancreatitis Open
Background Ductal features alone may not offer high diagnostic sensitivity or most accurate disease severity of chronic pancreatitis (CP). Purpose Diagnose CP based on multiparametric MRI and MRCP features. Study Type Prospective. Populati…
View article: A social media game to increase physical activity among older adult women: protocol of a randomized controlled trial to evaluate CHALLENGE
A social media game to increase physical activity among older adult women: protocol of a randomized controlled trial to evaluate CHALLENGE Open
ClinicalTrials.gov Identifier NCT04095923. Registered September 17th, 2019.
View article: BMRK-01 EXTERNALLY VALIDATED PREDICTIVE NOMOGRAM FOR BRAIN METASTASIS IN EARLY-STAGE BREAST CANCER
BMRK-01 EXTERNALLY VALIDATED PREDICTIVE NOMOGRAM FOR BRAIN METASTASIS IN EARLY-STAGE BREAST CANCER Open
BACKGROUND Brain metastasis presents a significant concern for early-stage breast cancer (ESBC) patients, impacting their survival and overall well-being. Constructing a predictive nomogram based on primary tumor characteristics offers a w…
View article: Patient-reported convenience and effectiveness of telehealth for breast cancer management
Patient-reported convenience and effectiveness of telehealth for breast cancer management Open
Background Before the coronavirus disease 2019 (COVID-19) pandemic, telehealth was rarely used for breast cancer management at tertiary care centers. We sought to examine patient satisfaction, experiences, preferences, and perceived effect…
View article: Identification of a Single-Dose, Low-Flip-Angle–Based CBV Threshold for Fractional Tumor Burden Mapping in Recurrent Glioblastoma
Identification of a Single-Dose, Low-Flip-Angle–Based CBV Threshold for Fractional Tumor Burden Mapping in Recurrent Glioblastoma Open
For LFA-based FTB maps, an sRCBV threshold of 1.0 and 1.37 can differentiate PTRE from recurrent tumors. FTB maps aid in surgical planning, guiding pathologic diagnosis and treatment strategies in the recurrent setting. This study further …
View article: Associations Between Stress, Health Behaviors, and Quality of Life in Young Couples During the Transition to Survivorship: Protocol for a Measurement Burst Study
Associations Between Stress, Health Behaviors, and Quality of Life in Young Couples During the Transition to Survivorship: Protocol for a Measurement Burst Study Open
Background Cancer is a life-threatening, stressful event, particularly for young adults due to delays and disruptions in their developmental transitions. Cancer treatment can also cause adverse long-term effects, chronic conditions, psycho…
View article: Associations Between Stress, Health Behaviors, and Quality of Life in Young Couples During the Transition to Survivorship: Protocol for a Measurement Burst Study (Preprint)
Associations Between Stress, Health Behaviors, and Quality of Life in Young Couples During the Transition to Survivorship: Protocol for a Measurement Burst Study (Preprint) Open
BACKGROUND Cancer is a life-threatening, stressful event, particularly for young adults due to delays and disruptions in their developmental transitions. Cancer treatment can also cause adverse long-term effects, chronic conditions, psych…
View article: Incidence and Risk Factors for Pneumonitis Associated With Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer: A Single Center Experience
Incidence and Risk Factors for Pneumonitis Associated With Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer: A Single Center Experience Open
Introduction Immune checkpoint inhibitor (ICI) pneumonitis causes substantial morbidity and mortality. Estimates of real-world incidence and reported risk factors vary substantially. Methods We conducted a retrospective review of 419 patie…
View article: Effect of dexamethasone on dyspnoea in patients with cancer (ABCD): a parallel-group, double-blind, randomised, controlled trial
Effect of dexamethasone on dyspnoea in patients with cancer (ABCD): a parallel-group, double-blind, randomised, controlled trial Open
View article: Interdisciplinary intervention for the management of nonmedical opioid use among patients with cancer pain
Interdisciplinary intervention for the management of nonmedical opioid use among patients with cancer pain Open
Background Few studies have assessed interventions aimed at managing nonmedical opioid use (NMOU) behavior among patients with cancer. The authors developed the Compassionate High‐Alert Team (CHAT) intervention to manage patients receiving…
View article: Pneumonitis after immune checkpoint inhibitor therapies in patients with acute myeloid leukemia: A retrospective cohort study
Pneumonitis after immune checkpoint inhibitor therapies in patients with acute myeloid leukemia: A retrospective cohort study Open
Background Immune checkpoint inhibitors (ICI), combined with hypomethylating agents, can be used to treat acute myeloid leukemia (AML), but this strategy results in a high rate of pneumonitis. The authors sought to determine risk factors f…
View article: Definitive Intensity-Modulated Chemoradiation for Anal Squamous Cell Carcinoma: Outcomes and Toxicity of 428 Patients Treated at a Single Institution
Definitive Intensity-Modulated Chemoradiation for Anal Squamous Cell Carcinoma: Outcomes and Toxicity of 428 Patients Treated at a Single Institution Open
Background Although intensity-modulated radiation therapy (IMRT) is considered the standard of care for the treatment of squamous cell carcinoma of the anus (SCCA), few large series have reported oncologic outcomes and toxicities. In this …
View article: Physical activity during the SARS‐CoV‐2 pandemic is linked to better mood and emotion
Physical activity during the SARS‐CoV‐2 pandemic is linked to better mood and emotion Open
The SARS‐CoV‐2 pandemic may negatively impact mood and emotion. Physical activity may protect against mood disturbance and promote positive affect. This study asked if physical activity before, during, or the change in physical activity wi…
View article: THE ASSOCIATION OF VOXEL-LEVEL LUNG DEFORMATION INDICES WITH AIRFLOW OBSTRUCTION IN POST-HEMATOPOIETIC CELL TRANSPLANTATION BRONCHIOLITIS OBLITERANS SYNDROME
THE ASSOCIATION OF VOXEL-LEVEL LUNG DEFORMATION INDICES WITH AIRFLOW OBSTRUCTION IN POST-HEMATOPOIETIC CELL TRANSPLANTATION BRONCHIOLITIS OBLITERANS SYNDROME Open
View article: Effect of the lysosomotropic agent chloroquine on mTORC1 activation and protein synthesis in human skeletal muscle
Effect of the lysosomotropic agent chloroquine on mTORC1 activation and protein synthesis in human skeletal muscle Open
Background Previous work in HEK-293 cells demonstrated the importance of amino acid-induced mTORC1 translocation to the lysosomal surface for stimulating mTORC1 kinase activity and protein synthesis. This study tested the conservation of t…
View article: T-cell responses to acute cardiorespiratory or resistance exercise in cohorts of physically active or physically inactive older adults: A randomized complete crossover
T-cell responses to acute cardiorespiratory or resistance exercise in cohorts of physically active or physically inactive older adults: A randomized complete crossover Open
Aging is associated with many chronic diseases that are maintained and perpetuated by immune dysregulation and chronic systemic inflammation. T-cells often undergo age-related changes, including an accumulation of memory cells, which place…
View article: A Short-Term Paleolithic Dietary Intervention Does Not Alter Adipokines Linked to Adiposity
A Short-Term Paleolithic Dietary Intervention Does Not Alter Adipokines Linked to Adiposity Open
It is possible that although eight weeks resulted in modest body composition changes, short-term fat loss will not induce changes in adiponectin, omentin, and nesfatin in apparently healthy adults. Larger, long-term intervention studies th…
View article: Effect of Electronic Activity Monitors and Pedometers on Health: Results from the TAME Health Pilot Randomized Pragmatic Trial
Effect of Electronic Activity Monitors and Pedometers on Health: Results from the TAME Health Pilot Randomized Pragmatic Trial Open
Background: Brief counseling and self-monitoring with a pedometer are common practice within primary care for physical activity promotion. It is unknown how high-tech electronic activity monitors compare to pedometers within this setting. …
View article: Accelerated Failure Time Survival Model to Analyze Morris Water Maze Latency Data
Accelerated Failure Time Survival Model to Analyze Morris Water Maze Latency Data Open
Traumatic brain injury (TBI) induces cognitive deficits clinically and in animal models. Learning and memory testing is critical when evaluating potential therapeutic strategies and treatments to manage the effects of TBI. We evaluated thr…
View article: Comparing Acute Aerobic vs. Resistance Exercise (CAARE) in young and older adults: Design and methods of a randomized acute exercise trial on the immune system
Comparing Acute Aerobic vs. Resistance Exercise (CAARE) in young and older adults: Design and methods of a randomized acute exercise trial on the immune system Open
Background: It is well accepted that exercise has numerous health benefits, including reducing the risk of developing cardiometabolic diseases and supporting a healthy immune system. Although these benefits are widely recognized, variation…
View article: Single-Arm 8-Week Ad Libitum Self-Prepared Paleo Diet Reduces Cardiometabolic Disease Risk Factors in Overweight Adults
Single-Arm 8-Week Ad Libitum Self-Prepared Paleo Diet Reduces Cardiometabolic Disease Risk Factors in Overweight Adults Open
The paleo diet is popular among the general population due to promoted weight loss and disease prevention benefits. We examined the effectiveness of a self-administered paleo diet in improving cardiometabolic disease risk factors. Overweig…
View article: Effect of Aerobic Exercise Training and Essential Amino Acid Supplementation for 24 Weeks on Physical Function, Body Composition, and Muscle Metabolism in Healthy, Independent Older Adults: A Randomized Clinical Trial
Effect of Aerobic Exercise Training and Essential Amino Acid Supplementation for 24 Weeks on Physical Function, Body Composition, and Muscle Metabolism in Healthy, Independent Older Adults: A Randomized Clinical Trial Open
Background Essential amino acids (EAA) and aerobic exercise (AE) acutely and independently stimulate skeletal muscle protein anabolism in older adults. Objective In this Phase 1, double-blind, placebo-controlled, randomized clinical trial,…
View article: Long-term effect of critical illness after severe paediatric burn injury on cardiac function in adolescent survivors: an observational study
Long-term effect of critical illness after severe paediatric burn injury on cardiac function in adolescent survivors: an observational study Open
View article: The feasibility and RE-AIM evaluation of the TAME health pilot study
The feasibility and RE-AIM evaluation of the TAME health pilot study Open
View article: Nasopharyngeal microbiota in infants and changes during viral upper respiratory tract infection and acute otitis media
Nasopharyngeal microbiota in infants and changes during viral upper respiratory tract infection and acute otitis media Open
Otopathogen genera played the key roles in URI and AOM occurrences. Staphylococcus counteracts otopathogens thus Staphylococcal colonization may be beneficial, rather than harmful. While Sphingobium may play a role in preventing AOM compli…
View article: Effect of Home- and Community-Based Physical Activity Interventions on Physical Function Among Cancer Survivors: A Systematic Review and Meta-Analysis
Effect of Home- and Community-Based Physical Activity Interventions on Physical Function Among Cancer Survivors: A Systematic Review and Meta-Analysis Open
View article: Feasibility and Acceptability of a Wearable Technology Physical Activity Intervention With Telephone Counseling for Mid-Aged and Older Adults: A Randomized Controlled Pilot Trial
Feasibility and Acceptability of a Wearable Technology Physical Activity Intervention With Telephone Counseling for Mid-Aged and Older Adults: A Randomized Controlled Pilot Trial Open
Clinicaltrials.gov NCT01869348; https://clinicaltrials.gov/ct2/show/NCT01869348 (Archived by WebCite at http://www.webcitation.org/6odlIolqy).
View article: Protein Supplementation Does Not Affect Myogenic Adaptations to Resistance Training
Protein Supplementation Does Not Affect Myogenic Adaptations to Resistance Training Open
Protein supplementation during resistance training has a modest effect on whole-body lean mass as compared with exercise training without protein supplementation, and there was no effect on any outcome between protein supplement types (ble…
View article: Soy-Dairy Protein Blend or Whey Protein Isolate Ingestion Induces Similar Postexercise Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis Responses in Older Men
Soy-Dairy Protein Blend or Whey Protein Isolate Ingestion Induces Similar Postexercise Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis Responses in Older Men Open