Kristýna Číhalová
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View article: Microrobots for Antibiotic-Resistant <i>Staphylococcus aureus</i> Skin Colony Eradication
Microrobots for Antibiotic-Resistant <i>Staphylococcus aureus</i> Skin Colony Eradication Open
Self-propelled nano- and micromachines have immense potential as autonomous seek-and-act devices in biomedical applications. In this study, we present microrobots constructed with inherently biocompatible materials and propulsion systems t…
View article: Antibacterial activity of the novel peptide Pac-525 with the RGD motif against intracellular Escherichia coli
Antibacterial activity of the novel peptide Pac-525 with the RGD motif against intracellular Escherichia coli Open
View article: Arrays of ultra-thin selenium-doped zirconium-anodic-oxide nanorods as potential antibacterial coatings
Arrays of ultra-thin selenium-doped zirconium-anodic-oxide nanorods as potential antibacterial coatings Open
Self-organized growth of extraordinarily thin/sharp ZrO 2 nanorods doped with Se species and advanced bactericidal properties was achieved via the anodization of Al/Zr bilayers in selenic acid electrolyte.
View article: Metabolic adaptations of Escherichia coli to extended zinc exposure: insights into tricarboxylic acid cycle and trehalose synthesis
Metabolic adaptations of Escherichia coli to extended zinc exposure: insights into tricarboxylic acid cycle and trehalose synthesis Open
View article: The immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus
The immune factors involved in the rapid clearance of bacteria from the midgut of the tick Ixodes ricinus Open
Ticks are obligate hematophagous arthropods that transmit a wide range of pathogens to humans as well as wild and domestic animals. They also harbor a non-pathogenic microbiota, although our previous study has shown that the diverse bacter…
View article: Insight into antibacterial effect of titanium nanotubular surfaces with focus on Staphylococcus aureus and Pseudomonas aeruginosa
Insight into antibacterial effect of titanium nanotubular surfaces with focus on Staphylococcus aureus and Pseudomonas aeruginosa Open
Materials used for orthopedic implants should not only have physical properties close to those of bones, durability and biocompatibility, but should also exhibit a sufficient degree of antibacterial functionality. Due to its excellent prop…
View article: Metabolic adaptations of Escherichia coli to extended zinc exposure: Insights into tricarboxylic acid cycle and trehalose synthesis
Metabolic adaptations of Escherichia coli to extended zinc exposure: Insights into tricarboxylic acid cycle and trehalose synthesis Open
Balanced bacterial metabolism is essential for cell homeostasis and growth and can be impacted by various stress factors. In this study, we investigated the impact of extended exposure of Escherichia coli to zinc oxide (ZnO40) and zinc oxi…
View article: Biopolymeric fibers prepared by centrifugal spinning blended with ZnO nanoparticles for the treatment of Acne vulgaris
Biopolymeric fibers prepared by centrifugal spinning blended with ZnO nanoparticles for the treatment of Acne vulgaris Open
Acne vulgaris is a serious dermatological disease affecting a significant part of the population. Currently, available therapeutics are effective only at high concentrations, which has a negative environmental and economic impact. In parti…
View article: Escherichia coli from Human Wounds: Analysis of Resistance to β-Lactams and Expression of RND Efflux Pumps
Escherichia coli from Human Wounds: Analysis of Resistance to β-Lactams and Expression of RND Efflux Pumps Open
Each E. coli isolate displayed unique characteristics, differing in minimum inhibitory concentration (MIC) values, prevalence of acquired blaTEM and blaCTX-M genes, and expression of the RND-family pumps. This together…
View article: Zinc effects on bacteria: insights from <i>Escherichia coli</i> by multi-omics approach
Zinc effects on bacteria: insights from <i>Escherichia coli</i> by multi-omics approach Open
In this study, we investigated the impact of zinc oxide (ZnO) and zinc oxide nanoparticles (ZnONPs) on Escherichia coli . These compounds are commonly used as fertilizers and feed additives and may have unintended consequences on bacteria.…
View article: Platinum nanoparticles induce damage to DNA and inhibit DNA replication
Platinum nanoparticles induce damage to DNA and inhibit DNA replication Open
Sparsely tested group of platinum nanoparticles (PtNPs) may have a comparable effect as complex platinum compounds. The aim of this study was to observe the effect of PtNPs in in vitro amplification of DNA fragment of phage λ, on the bacte…
View article: Influence of microbiome species in hard-to-heal wounds on disease severity and treatment duration
Influence of microbiome species in hard-to-heal wounds on disease severity and treatment duration Open
View article: Staphylococcus aureus and MRSA Growth and Biofilm Formation after Treatment with Antibiotics and SeNPs
Staphylococcus aureus and MRSA Growth and Biofilm Formation after Treatment with Antibiotics and SeNPs Open
Methicillin-resistant Staphylococcus aureus (MRSA) is a dangerous pathogen resistant to β-lactam antibiotics. Due to its resistance, it is difficult to manage the infections caused by this strain. We examined this issue in terms of observa…
View article: Prion protein and its interactions with metal ions (Cu2+, Zn2+, and Cd2+) and metallothionein 3
Prion protein and its interactions with metal ions (Cu2+, Zn2+, and Cd2+) and metallothionein 3 Open
The effects of heavy metals (Zn2+, Cu2+, and/or Cd2+) on Escherichia coli expressing either prion (hPrP(C)) or metallothionein 3 (MT-3) brain proteins capable of binding these metals were investigated. The expression of hPrPC or MT-3 in E.…
View article: Effects of Stratospheric Conditions on the Viability, Metabolism and Proteome of Prokaryotic Cells
Effects of Stratospheric Conditions on the Viability, Metabolism and Proteome of Prokaryotic Cells Open
The application of ultraviolet (UV) radiation to inhibit bacterial growth is based on the principle that the exposure of DNA to UV radiation results in the formation of cytotoxic lesions, leading to inactivation of microorganisms. Herein, …
View article: Biological Activity and Molecular Structures of Bis(benzimidazole) and Trithiocyanurate Complexes
Biological Activity and Molecular Structures of Bis(benzimidazole) and Trithiocyanurate Complexes Open
1-(1H-Benzimidazol-2-yl)-N-(1H-benzimidazol-2-ylmethyl)methanamine (abb) and 2-(1H-benzimidazol-2-ylmethylsulfanylmethyl)-1H-benzimidazole (tbb) have been prepared and characterized by elemental analysis. These bis(benzimidazoles) have bee…
View article: The Composites of Graphene Oxide with Metal or Semimetal Nanoparticles and Their Effect on Pathogenic Microorganisms
The Composites of Graphene Oxide with Metal or Semimetal Nanoparticles and Their Effect on Pathogenic Microorganisms Open
The present experiment describes a synthesis process of composites based on graphene oxide, which was tested as a carrier for composites of metal- or metalloid-based nanoparticles (Cu, Zn, Mn, Ag, AgP, Se) and subsequently examined as an a…
View article: Study of Linkage between Glutathione Pathway and the Antibiotic Resistance of Escherichia coli from Patients’ Swabs
Study of Linkage between Glutathione Pathway and the Antibiotic Resistance of Escherichia coli from Patients’ Swabs Open
In this work, we focused on the differences between bacterial cultures of E. coli obtained from swabs of infectious wounds of patients compared to laboratory E. coli. In addition, blocking of the protein responsible for the synthesis of gl…
View article: Antimicrobial nanomaterials in the food industry.
Antimicrobial nanomaterials in the food industry. Open
Nanoparticles of metals interacting with cellular components and biomacromolecules including DNA and RNA alter cellular processes. Concerning the antimicrobial activity, the metal nanoparticles in nanomolar concentrations inhibit the growt…
View article: CCDC 1033060: Experimental Crystal Structure Determination
CCDC 1033060: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1033059: Experimental Crystal Structure Determination
CCDC 1033059: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …