Krithika R. Subramanian
YOU?
Author Swipe
View article: Splicing regulatory dynamics for precision analysis and treatment of heterogeneous leukemias
Splicing regulatory dynamics for precision analysis and treatment of heterogeneous leukemias Open
The role of splicing dysregulation in cancer is underscored by splicing factor mutations; however, its impact in the absence of such rare mutations remains poorly understood. Prompted by the finding that splicing uniquely resolved genetic …
View article: Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation Open
The role of splicing dysregulation in cancer is underscored by splicing factor mutations; however, its impact in the absence of such rare mutations is poorly understood. To reveal complex patient subtypes and putative regulators of pathoge…
View article: Ontogeny and function of the circadian clock in intestinal organoids
Ontogeny and function of the circadian clock in intestinal organoids Open
View article: Ontogeny and function of the circadian clock in intestinal organoids
Ontogeny and function of the circadian clock in intestinal organoids Open
Circadian rhythms regulate diverse aspects of gastrointestinal physiology ranging from the composition of microbiota to motility. However, development of the intestinal circadian clock and detailed molecular mechanisms regulating circadian…