Kshitiz Parihar
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View article: Tissue-dependent mechanosensing by cells derived from human tumors
Tissue-dependent mechanosensing by cells derived from human tumors Open
Alterations of the extracellular matrix (ECM), including both mechanical (such as stiffening of the ECM) and chemical (such as variation of adhesion proteins and deposition of hyaluronic acid (HA)) changes, in malignant tissues have been s…
View article: Tissue-dependent mechanosensing by cells derived from human tumors
Tissue-dependent mechanosensing by cells derived from human tumors Open
Alterations of the extracellular matrix (ECM), including both mechanical (such as stiffening of the ECM) and chemical (such as variation of adhesion proteins and deposition of hyaluronic acid (HA)) changes, in malignant tissues have been s…
View article: Enzyme-Regulated Non-Thermal Fluctuations Enhance Ligand Diffusion and Receptor-Mediated Endocytosis
Enzyme-Regulated Non-Thermal Fluctuations Enhance Ligand Diffusion and Receptor-Mediated Endocytosis Open
Active enzymes during catalyzing chemical reactions, have been found to generate significant mechanical fluctuations, which can influence the dynamics of their surroundings. These phenomena open new avenues for controlling mass transport i…
View article: Asymmetric crowders and membrane morphology at the nexus of intracellular trafficking and oncology
Asymmetric crowders and membrane morphology at the nexus of intracellular trafficking and oncology Open
A definitive understanding of the interplay between protein binding/migration and membrane curvature evolution is emerging but needs further study. The mechanisms defining such phenomena are critical to intracellular transport and traffick…