K.T. Chan
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View article: Atopic dermatitis epidemiological research methodology: a global scoping review
Atopic dermatitis epidemiological research methodology: a global scoping review Open
Background Atopic dermatitis (AD) has the highest burden of all skin diseases globally. While numerous systematic reviews and meta-analyses have attempted to estimate the burden of AD at country, regional and global levels, the variability…
View article: A pan-European register-based observational study of abrocitinib and conventional systemic therapies in moderate and severe atopic dermatitis: the DREAM TO TREAT AD study protocol
A pan-European register-based observational study of abrocitinib and conventional systemic therapies in moderate and severe atopic dermatitis: the DREAM TO TREAT AD study protocol Open
Background Atopic dermatitis (AD) is a common chronic inflammatory skin condition. Currently, there is a lack of real-world evidence regarding the effectiveness of systemic therapies for moderate-to-severe AD. Abrocitinib is a novel Janus …
View article: Direct and Indirect Protein Interactions Link FUS Aggregation to Histone Post-Translational Modification Dysregulation and Growth Suppression in an ALS/FTD Yeast Model
Direct and Indirect Protein Interactions Link FUS Aggregation to Histone Post-Translational Modification Dysregulation and Growth Suppression in an ALS/FTD Yeast Model Open
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are incurable neurodegenerative disorders sharing pathological and genetic features, including mutations in the FUS gene. FUS is an RNA-binding protein that mislocalizes…
View article: Crispri Essentiality Screen Reveals the Essential Enhancers and Oncogenes Comprising the “Regulome” of the Notch-Collaborating Transcription Factor ETS1 in Human T-ALL
Crispri Essentiality Screen Reveals the Essential Enhancers and Oncogenes Comprising the “Regulome” of the Notch-Collaborating Transcription Factor ETS1 in Human T-ALL Open
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive lymphoid malignancy derived from immature T cells. No targeted therapies are currently available. Although over 60% of T-ALL samples carry activating mutations in the Notch signa…
View article: Glycaemic control and microvascular complications among paediatric type 2 diabetes mellitus patients in Hong Kong at 2 years after diagnosis
Glycaemic control and microvascular complications among paediatric type 2 diabetes mellitus patients in Hong Kong at 2 years after diagnosis Open
These results highlight the importance of early diagnosis and holistic management (including co-morbidity management) for paediatric T2DM patients.
View article: Study of Heating and Evaporation of Rotating Graphene Nanofluid under the Influence of Solar Radiation
Study of Heating and Evaporation of Rotating Graphene Nanofluid under the Influence of Solar Radiation Open
Conversion of solar radiation into steam is presently one of the trends in “green” energy (solar thermal energy), ecology, and clean water production. For the first time, a study of the heating and evaporation of a rotating graphene nanofl…
View article: Probabilistic and electricity saving analyses of Mist Coolers for Chiller System in a Hotel
Probabilistic and electricity saving analyses of Mist Coolers for Chiller System in a Hotel Open
1st Joint Conference on World Engineers Summit - Applied Energy Symposium and Forum: Low Carbon Cities and Urban Energy, WES-CUE 2017, Singapore, 19-21 2017
View article: Metallic Glasses
Metallic Glasses Open
de Barcelona (UAB), where he leads the Group of Smart Nanoengineered Materials, Nanomechanics and Nanomagnetism (Gnm3) (2014-SGR-1015