Kuiqing Cui
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View article: Epidemiological Investigation on Pathogenic Bacteria of Buffalo Subclinical Mastitis and Their Antibiotic Resistance and Virulence Characteristics in Guangxi, China
Epidemiological Investigation on Pathogenic Bacteria of Buffalo Subclinical Mastitis and Their Antibiotic Resistance and Virulence Characteristics in Guangxi, China Open
Subclinical mastitis (SCM) is one of the most common and detrimental diseases affecting dairy cows, causing lower milk yield and quality. Identification of pathogenic bacteria of subclinical mastitis (PSM) in dairy cows is crucial for sele…
View article: Analysis of flavor formation and metabolite changes during production of Double-Layer Steamed Milk Custard made from buffalo milk
Analysis of flavor formation and metabolite changes during production of Double-Layer Steamed Milk Custard made from buffalo milk Open
Double-Layer Steamed Milk Custard (DLSMC) is a famous traditional Chinese dessert. This study aimed to analyze the flavor and the changes in metabolites during different stages of DLSMC preparation, including raw buffalo milk, thermo-proce…
View article: Host-driven remodeling of rumen microbiota supports lactation metabolism in buffalo
Host-driven remodeling of rumen microbiota supports lactation metabolism in buffalo Open
Introduction Rumen microbiota and host metabolites play a key role in regulating ruminant production performance and physiological adaptation. However, the interplay between host physiological status and rumen microbial-metabolite dynamics…
View article: Revealing gene expression links between milk fat globules and mammary glands in rodents via transcriptomics
Revealing gene expression links between milk fat globules and mammary glands in rodents via transcriptomics Open
Currently, most studies on lactation-related traits and gene expression rely on invasive techniques to obtain mammary tissue. These methods are not only difficult to perform but also limit the availability of samples. Therefore, this study…
View article: Characterization of mammary glands and milk fat globule transcripts in lactating buffalo and goats
Characterization of mammary glands and milk fat globule transcripts in lactating buffalo and goats Open
Gene expression and post-transcriptional regulation are key mechanisms affecting lactation performance in dairy animals. However, the difficulty of obtaining mammary gland tissue samples from lactating animals has significantly impeded lac…
View article: The Microbial Diversity and Traceability Analysis of Raw Milk from Buffalo Farms at Different Management Ranks in Guangxi Province
The Microbial Diversity and Traceability Analysis of Raw Milk from Buffalo Farms at Different Management Ranks in Guangxi Province Open
Farm management has a significant impact on microbial composition and may affect the quality of raw buffalo milk. This study involved a diversity analysis and traceability of the microbial communities in raw buffalo milk from three buffalo…
View article: Exploration of transcriptional regulation network between buffalo oocytes and granulosa cells and its impact on different diameter follicles
Exploration of transcriptional regulation network between buffalo oocytes and granulosa cells and its impact on different diameter follicles Open
In summary, this study preliminarily revealed the differences in gene expression patterns among buffalo follicles of different sizes and their potential molecular regulatory mechanisms. It provides a new perspective for exploring the mecha…
View article: Meta-Genomic Analysis of Different Bacteria and Their Genomes Found in Raw Buffalo Milk Obtained in Various Farms Using Different Milking Methods
Meta-Genomic Analysis of Different Bacteria and Their Genomes Found in Raw Buffalo Milk Obtained in Various Farms Using Different Milking Methods Open
Milking methods have significant impacts on the microbiological composition, which could affect the quality of raw buffalo milk. Hence, the current study was conducted on the impact of milking methods on microorganisms in buffalo tank raw …
View article: A Characterization and Functional Analysis of Peroxisome Proliferator-Activated Receptor Gamma Splicing Variants in the Buffalo Mammary Gland
A Characterization and Functional Analysis of Peroxisome Proliferator-Activated Receptor Gamma Splicing Variants in the Buffalo Mammary Gland Open
Peroxisome proliferator-activated receptor γ (PPARG) has various splicing variants and plays essential roles in the regulation of adipocyte differentiation and lipogenesis. However, little is known about the expression pattern and effect o…
View article: Age-related compositional and functional changes in the adult and breastfed buffalo rumen microbiome
Age-related compositional and functional changes in the adult and breastfed buffalo rumen microbiome Open
Introduction The buffalo is an important domestic animal globally, providing milk, meat, and labor to more than 2 billion people in 67 countries. The rumen microorganisms of buffaloes play an indispensable role in enabling the healthy func…
View article: Multi-omics reveal the effects and regulatory mechanism of dietary neutral detergent fiber supplementation on carcass characteristics, amino acid profiles, and meat quality of finishing pigs
Multi-omics reveal the effects and regulatory mechanism of dietary neutral detergent fiber supplementation on carcass characteristics, amino acid profiles, and meat quality of finishing pigs Open
This study aimed to reveal the effects and regulatory mechanism of dietary NDF on the performance of pigs by multi-omics analysis. Results showed that 16 % dietary NDF significantly improved meat quality, increased flavor amino acid conten…
View article: Construction and Identification of a Breast Bioreactor for Human-Derived Hypoglycemic Protein Amylin
Construction and Identification of a Breast Bioreactor for Human-Derived Hypoglycemic Protein Amylin Open
The mammary gland of mammals can generate numerous bioactive proteins. To express the human amylin protein in the mammary glands of domestic animals, we engineered a transgenic mammary gland bioreactor. For this study, we produced transgen…
View article: A Circular RNA Generated from Nebulin (<i>NEB</i>) Gene Splicing Promotes Skeletal Muscle Myogenesis in Cattle as Detected by a Multi‐Omics Approach
A Circular RNA Generated from Nebulin (<i>NEB</i>) Gene Splicing Promotes Skeletal Muscle Myogenesis in Cattle as Detected by a Multi‐Omics Approach Open
Cattle and the draught force provided by its skeletal muscle have been integral to agro‐ecosystems of agricultural civilization for millennia. However, relatively little is known about the cattle muscle functional genomics (including prote…
View article: Role of Different Members of the AGPAT Gene Family in Milk Fat Synthesis in Bubalus bubalis
Role of Different Members of the AGPAT Gene Family in Milk Fat Synthesis in Bubalus bubalis Open
During triacylglycerol synthesis, the acylglycerol-3-phosphate acyltransferase (AGPAT) family catalyzes the conversion of lysophosphatidic acid to phosphatidic acid and the acylation of sn-2 fatty acids. However, the catalytic activity of …
View article: The multi-kingdom microbiome of the goat gastrointestinal tract
The multi-kingdom microbiome of the goat gastrointestinal tract Open
Background Goat is an important livestock worldwide, which plays an indispensable role in human life by providing meat, milk, fiber, and pelts. Despite recent significant advances in microbiome studies, a comprehensive survey on the goat m…
View article: Whole-genome transcriptome and DNA methylation dynamics of pre-implantation embryos reveal progression of embryonic genome activation in buffaloes
Whole-genome transcriptome and DNA methylation dynamics of pre-implantation embryos reveal progression of embryonic genome activation in buffaloes Open
View article: Additional file 1 of The multi-kingdom microbiome of the goat gastrointestinal tract
Additional file 1 of The multi-kingdom microbiome of the goat gastrointestinal tract Open
Additional file 1: Supplement Table S1-S9. Table S1. Detailed sampling information for 497 samples, Table S2. Number of gastrointestinal tract samples, Table S3. Number of age samples, Table S4. Number of feeding styles samples, Table S5. …
View article: High-Quality Genomes of Pangolins: Insights into the Molecular Basis of Scale Formation and Adaption to Myrmecophagous Diet
High-Quality Genomes of Pangolins: Insights into the Molecular Basis of Scale Formation and Adaption to Myrmecophagous Diet Open
Pangolins are one of nature's most fascinating species being scales covered and myrmecophagous diet, yet relatively little is known about the molecular basis. Here, we combine the multi-omics, evolution, and fundamental proteins feature an…
View article: Chromosome-level genome and recombination map of the male buffalo
Chromosome-level genome and recombination map of the male buffalo Open
Background The swamp buffalo (Bubalus bubalis carabanesis) is an economically important livestock supplying milk, meat, leather, and draft power. Several female buffalo genomes have been available, but the lack of high-quality male genomes…
View article: Molecular mechanisms underlying hematophagia revealed by comparative analyses of leech genomes
Molecular mechanisms underlying hematophagia revealed by comparative analyses of leech genomes Open
Background Leeches have been used in traditional Chinese medicine since prehistoric times to treat a spectrum of ailments, but very little is known about their physiological, genetic, and evolutionary characteristics. Findings We sequenced…
View article: Correction: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome
Correction: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome Open
View article: RNA-Seq Reveals the Underlying Molecular Mechanism of First Cleavage Time Affecting Porcine Embryo Development
RNA-Seq Reveals the Underlying Molecular Mechanism of First Cleavage Time Affecting Porcine Embryo Development Open
The selection and evaluation of high-quality embryos are the key factors affecting in vitro embryo development and pregnancy outcome. The timing of first embryonic cleavage has been considered a positive indicator of the in vitro developme…
View article: Generation of Heritable Prominent Double Muscle Buttock Rabbits via Novel Site Editing of Myostatin Gene Using CRISPR/Cas9 System
Generation of Heritable Prominent Double Muscle Buttock Rabbits via Novel Site Editing of Myostatin Gene Using CRISPR/Cas9 System Open
Rabbits have been domesticated for meat, wool, and fur production, and have also been cherished as a companion, artistic inspiration, and an experimental model to study many human diseases. In the present study, the muscle mass negative re…
View article: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome
Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome Open
View article: The microbiome of the buffalo digestive tract
The microbiome of the buffalo digestive tract Open
View article: [Retracted] Genomic and Therapeutic Analyses of Staphylococcus aureus Isolated from Cattle Reproductive Tract
[Retracted] Genomic and Therapeutic Analyses of Staphylococcus aureus Isolated from Cattle Reproductive Tract Open
Staphylococcus aureus is emerging as a ubiquitous multidrug‐resistant pathogen circulating among animals, humans, and their environment. The current study focused on molecular epidemiology and evidence‐based treatment against S. aureus fro…
View article: The Effect of PIS Region on Horned or Polled Phenotype Traits in China Guanzhong Dairy Goats
The Effect of PIS Region on Horned or Polled Phenotype Traits in China Guanzhong Dairy Goats Open
Gumminess, Cohesiveness, Hardness, Physicochemical characteristics of cheese, Functional characteristics of cheese, Textural profile of cheese, Low fat cheese.Low fat cheese is the demand of this era due to overconsumption and sedentary li…
View article: Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Energy Homeostasis of Dairy Animals: Exploiting Their Modulation through Nutrigenomic Interventions
Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Energy Homeostasis of Dairy Animals: Exploiting Their Modulation through Nutrigenomic Interventions Open
Peroxisome proliferator-activated receptors (PPARs) are the nuclear receptors that could mediate the nutrient-dependent transcriptional activation and regulate metabolic networks through energy homeostasis. However, these receptors cannot …
View article: Single-Cell RNA-Seq Revealed the Gene Expression Pattern during the In Vitro Maturation of Donkey Oocytes
Single-Cell RNA-Seq Revealed the Gene Expression Pattern during the In Vitro Maturation of Donkey Oocytes Open
Donkeys are an important domesticated animal, providing labor, meat, milk, and medicinal materials for humans. However, the donkey population is continuously declining and even at risk of extinction. The application of modern animal produc…
View article: High-quality reference genome of Fasciola gigantica: Insights into the genomic signatures of transposon-mediated evolution and specific parasitic adaption in tropical regions
High-quality reference genome of Fasciola gigantica: Insights into the genomic signatures of transposon-mediated evolution and specific parasitic adaption in tropical regions Open
Fasciola gigantica and Fasciola hepatica are causative pathogens of fascioliasis , with the widest latitudinal, longitudinal, and altitudinal distribution; however, among parasites, they have the largest sequenced genomes, hindering genomi…