Kunal Gala
YOU?
Author Swipe
View article: Primary non-hepatoblastoma liver tumors in children—Defining the profile of a very rare subset of childhood tumors
Primary non-hepatoblastoma liver tumors in children—Defining the profile of a very rare subset of childhood tumors Open
Background Primary pediatric non-hepatoblastoma (n-HB) liver tumors are rare with limited literature on their clinical-epidemiological profile and outcomes. We audit the above in this study. Methods Children diagnosed with n-HB primary liv…
View article: Genomic landscape of hormone therapy-resistant HR-positive, HER2-negative breast cancer
Genomic landscape of hormone therapy-resistant HR-positive, HER2-negative breast cancer Open
Hormone therapy-resistant HR+/HER2-negative breast cancers are polyclonal, acquire actionable alterations at relapse, and moderate-depth ctDNA successfully identifies many clonal mutations, suggesting a role for liquid biopsy monitoring in…
View article: Changing paradigms in pediatric cancer care – the contemporary landscape and perspectives for India
Changing paradigms in pediatric cancer care – the contemporary landscape and perspectives for India Open
Advances in the diagnosis and management of childhood cancers have significantly improved survival, and 80% of those who have access to contemporary treatment are expected to survive into adulthood. Multimodality protocols incorporating hi…
View article: Real-World Surgical Experience with Thoracic Solitary Fibrous Tumors: Outcomes from a High-Volume Indian Center
Real-World Surgical Experience with Thoracic Solitary Fibrous Tumors: Outcomes from a High-Volume Indian Center Open
This study evaluates the surgical approach, role of trans-arterial angioembolization (TAE) and long-term outcomes of patients presenting with solitary fibrous tumors (SFT) to a tertiary thoracic surgical unit in India. This is a retrospect…
View article: Pelvic Compartments and Imaging Considerations Beyond TME Surgery for Rectal Cancer Patients
Pelvic Compartments and Imaging Considerations Beyond TME Surgery for Rectal Cancer Patients Open
The rectum resides next to multiple important organs, muscles, nodes, nerves, and vessels. While operating in the mesorectal plane is sacrosanct for a successful rectal cancer surgery to obtain a negative circumferential resection margin a…
View article: Impact of Interventional Radiology in Modern-Day Pancreatic Surgery
Impact of Interventional Radiology in Modern-Day Pancreatic Surgery Open
To evaluate the role of interventional radiology (IR) in modern-day pancreatic surgery. Study design: An audit of prospectively maintained electronic medical records. Duration of study: All patients who required image-guided interventions …
View article: Unique CT Imaging Features of Congenital Mesoblastic Nephroma: Insights from a Case Series and Literature Review
Unique CT Imaging Features of Congenital Mesoblastic Nephroma: Insights from a Case Series and Literature Review Open
Congenital mesoblastic nephroma (CMN) is a rare pediatric renal neoplasm, affecting primarily infants, accounting for 3 to 6% of pediatric renal tumors. It is subdivided into three variants: classic, cellular, and mixed, each demonstrating…
View article: Prognostic Modeling for Bone Sarcomas Based on a Large Prospective Cohort From a Tertiary Care Cancer Center in India
Prognostic Modeling for Bone Sarcomas Based on a Large Prospective Cohort From a Tertiary Care Cancer Center in India Open
PURPOSE Outcomes of adolescents and young adults (AYA) with bone sarcomas including osteosarcoma (OGS) and Ewing sarcoma (ES) are affected by various factors including inadvertent previous treatment and poor compliance. We aimed to develop…
View article: Role of preoperative transarterial chemoembolization (TACE) in intermediate‐stage hepatocellular carcinoma (Hong Kong liver cancer stage IIB)
Role of preoperative transarterial chemoembolization (TACE) in intermediate‐stage hepatocellular carcinoma (Hong Kong liver cancer stage IIB) Open
Introduction Transarterial chemoembolization (TACE) has an established role in advanced HCC. The present study evaluates the role of TACE as a neoadjuvant modality in the management of intermediate HCC [Hong Kong Liver Cancer (HKLC) stage …
View article: Ten‐year follow‐up of outcomes, patterns of care, and psychosocial burden in adolescent and young adult patients with bone sarcomas from a large cohort in a low‐income and middle‐income country
Ten‐year follow‐up of outcomes, patterns of care, and psychosocial burden in adolescent and young adult patients with bone sarcomas from a large cohort in a low‐income and middle‐income country Open
Background The care of adolescents and young adults (AYAs) with bone sarcomas involves unique challenges. The objectives of this study were to identify challenges and evaluate long‐term outcomes of these patients from India who received tr…
View article: Realizing Textbook Outcomes Following Liver Resection for Hepatic Neoplasms with Development and Validation of a Predictive Nomogram
Realizing Textbook Outcomes Following Liver Resection for Hepatic Neoplasms with Development and Validation of a Predictive Nomogram Open
Background ‘Textbook Outcome’ (TO) represents an effort to define a standardized, composite quality benchmark based on intraoperative and postoperative endpoints. This study aimed to assess the applicability of TO as an outcome measure fol…
View article: Evaluation and Management of Unresectable Hepatocellular Carcinoma: Multidisciplinary Indian Consensus Statements from a Delphi Panel
Evaluation and Management of Unresectable Hepatocellular Carcinoma: Multidisciplinary Indian Consensus Statements from a Delphi Panel Open
India, like many parts of Asia, likely faces a high burden of hepatocellular carcinoma (HCC), though large-scale data on etiology, presentation, and outcomes are lacking. There appears to be a predominance of unresectable, advanced-stage H…
View article: Impact of post-hepatectomy biliary leaks on long-term survival in different liver tumors: A single institute experience
Impact of post-hepatectomy biliary leaks on long-term survival in different liver tumors: A single institute experience Open
Post-hepatectomy biliary leaks are associated with significantly poorer DFS only in patients with cholangiocarcinoma, but not in patients with hepatocellular carcinoma or metastatic colorectal cancer. Methods to mitigate this survival detr…
View article: Retrospective Study of Multimodality Imaging Features of Chondroblastoma
Retrospective Study of Multimodality Imaging Features of Chondroblastoma Open
Purpose To evaluate the multimodality imaging features of chondroblastoma. Materials and Methods Retrospective analysis of imaging features of 52 cases of histopathologically proven chondroblastoma from 2010 to 2022 was performed. Radiogra…
View article: Radiation Safety Assessment of 177Lu-DOTATATE Intra-arterial Peptide Receptor Therapy (PRRT)
Radiation Safety Assessment of 177Lu-DOTATATE Intra-arterial Peptide Receptor Therapy (PRRT) Open
Objective: 177 Lu-DOTATATE peptide receptor therapy (PRRT) is an established treatment for patients suffering from neuroendocrine tumors. In the last few years, intra-arterial PRRT is being considered for patients having liver metastatic d…
View article: Accuracy of contrast-enhanced CT in liver neoplasms in children under 2 years age
Accuracy of contrast-enhanced CT in liver neoplasms in children under 2 years age Open
Background Multiple differentials exist for pediatric liver tumors under 2 years. Accurate imaging diagnosis may obviate the need for tissue sampling in most cases. Objective To evaluate the imaging features and diagnostic accuracy of comp…
View article: Evaluation of Metronomic Therapy as a Low-Cost, Sustainable, Standard-of-Care Option in Desmoid Fibromatosis: Real-World Data From a Tertiary Care Center in India
Evaluation of Metronomic Therapy as a Low-Cost, Sustainable, Standard-of-Care Option in Desmoid Fibromatosis: Real-World Data From a Tertiary Care Center in India Open
PURPOSE Desmoid fibromatosis (DF) is a locally aggressive tumor with low mortality but significant morbidity. There is a lack of standard of care, and existing therapies are associated with significant barriers including access, cost, and …
View article: Prognostic Modeling for Bone Sarcomas based on a Large Prospective Cohort from a Tertiary Care Cancer Centre in India
Prognostic Modeling for Bone Sarcomas based on a Large Prospective Cohort from a Tertiary Care Cancer Centre in India Open
Background: Outcomes of adolescents and young adults (AYA) with bone sarcomas inclusive of osteosarcoma (OGS) and Ewing’s sarcoma (ES) are impacted by various factors including inadvertent prior treatment and poor compliance. We aimed to i…
View article: Role of EBUS-TBNA in Mediastinal Staging of NSCLC Patients
Role of EBUS-TBNA in Mediastinal Staging of NSCLC Patients Open
Purpose Mediastinal staging in non-small-cell lung carcinoma (NSCLC) is essential for appropriate treatment. Invasive mediastinal staging is necessary and mediastinoscopy has been the gold standard, but it is associated with morbidity. The…
View article: Intra-arterial PRRT with Lu-177 DOTATATE in Liver-dominant Metastatic Neuroendocrine Tumors: Early Assessment of Efficacy and Toxicity
Intra-arterial PRRT with Lu-177 DOTATATE in Liver-dominant Metastatic Neuroendocrine Tumors: Early Assessment of Efficacy and Toxicity Open
Purpose: We proposed to administer Lu-177-DOTATATE in intra-arterial (IA) mode for higher first-pass localization to somatostatin receptors, higher residence time in liver metastases, and more radiation to tumor. This study aimed at assess…
View article: PRRT with Lu-177 DOTATATE in Treatment-Refractory Progressive Meningioma: Initial Experience from a Tertiary-Care Neuro-Oncology Center
PRRT with Lu-177 DOTATATE in Treatment-Refractory Progressive Meningioma: Initial Experience from a Tertiary-Care Neuro-Oncology Center Open
Purpose: Refractory and/or recurrent meningiomas have poor outcomes, and the treatment options are limited. Peptide receptor radionuclide therapy (PRRT) has been used in this setting with promising results. We have documented our experienc…