Kunio Kitamura
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View article: Efficacy and safety of drospirenone as a progestin‐only pill in Japanese women: A phase <scp>III</scp> study
Efficacy and safety of drospirenone as a progestin‐only pill in Japanese women: A phase <span>III</span> study Open
Aim To evaluate the efficacy and safety of 4 mg of drospirenone (DRSP), a progestin‐only pill (POP), for contraception in Japanese women. Methods This was a multicenter, open‐label, single‐arm study. The dosing period of DRSP was 13 cycles…
View article: A phase I/II study evaluating the pharmacokinetics, pharmacodynamics, and safety of drospirenone as an oral contraceptive in Japanese women
A phase I/II study evaluating the pharmacokinetics, pharmacodynamics, and safety of drospirenone as an oral contraceptive in Japanese women Open
Aim Drospirenone (DRSP) is a synthetic progestogen approved as a progestin‐only pill for contraception in both the United States and Europe. Herein, we conducted a phase I/II study to evaluate the pharmacokinetics, pharmacodynamics, and sa…
View article: <i>MYD88</i> mutation-positive indolent B-cell lymphoma with CNS involvement: Bing–Neel syndrome mimickers
<i>MYD88</i> mutation-positive indolent B-cell lymphoma with CNS involvement: Bing–Neel syndrome mimickers Open
MYD88 p.L265P mutation occurs in over 90% of Waldenström's macroglobulinemia (WM), which is characterized by lymphoplasmacytic lymphoma (LPL) with monoclonal IgM. WM requires careful diagnosis due to overlapping features with other B-cell …
View article: Multi-Lineage BCR-ABL Expression in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Is Associated With Improved Prognosis but No Specific Molecular Features
Multi-Lineage BCR-ABL Expression in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Is Associated With Improved Prognosis but No Specific Molecular Features Open
We confirmed that more than one-third of Ph+ALL patients could be classified as mutli-Ph. Although no specific molecular characteristics were identified for multi-Ph, this phenotype was associated with better treatment outcomes.
View article: Clinical Significance of Wt1 mRNA Levels in Japanese Acute Lymphoblastic Leukemia Patients
Clinical Significance of Wt1 mRNA Levels in Japanese Acute Lymphoblastic Leukemia Patients Open
This study enrolled 49 patients with de novo childhood acute lymphoblastic leukemia (ALL) and 19 adult patients with ALL. WT1 mRNA showed high positive expression rates of 90% or more in ALL patients, and fusion gene transcripts were detec…