Kunna Lu
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View article: Study of independent diagnostic efficacy and co-diagnostic strategies of molecular markers for diabetic cardiomyopathy
Study of independent diagnostic efficacy and co-diagnostic strategies of molecular markers for diabetic cardiomyopathy Open
Word count of the full article: 4834Diabetic cardiomyopathy (DCM) is defined as myocardial dysfunction in diabetes mellitus (DM) patients independent of coronary artery disease (CAD) or hypertension (HTN). With high morbidity and mortality…
View article: Impact of DHEA supplementation on testosterone and estradiol levels in postmenopausal women: a meta-analysis of randomized controlled trials assessing dose and duration effects
Impact of DHEA supplementation on testosterone and estradiol levels in postmenopausal women: a meta-analysis of randomized controlled trials assessing dose and duration effects Open
DHEA supplementation at doses ≥ 50 mg/day significantly increases testosterone levels in postmenopausal women. Moreover, in women aged ≥ 60 years, supplementation at the same dosage significantly elevates estradiol levels.
View article: Bioinformatics analysis identifies immune-related gene signatures and subtypes in diabetic nephropathy
Bioinformatics analysis identifies immune-related gene signatures and subtypes in diabetic nephropathy Open
Background Systemic inflammation and immune response are involved in the pathogenesis of diabetic nephropathy (DN). However, the specific immune-associated signature during DN development is unclear. Our study aimed to reveal the roles of …
View article: Effect of a high vs. standard dose of vitamin D3 supplementation on bone metabolism and kidney function in children with chronic kidney disease
Effect of a high vs. standard dose of vitamin D3 supplementation on bone metabolism and kidney function in children with chronic kidney disease Open
We investigated the effects of high- vs. standard-dose vitamin D supplementation on kidney function and bone metabolism in children with chronic kidney disease (CKD). Children were randomized to receive one of two formulations: 75 particip…
View article: Effect of Higher vs Standard Dosage of Vitamin D3 Supplementation on Bone Strength and bone metabolism in child with chronic kidney disease
Effect of Higher vs Standard Dosage of Vitamin D3 Supplementation on Bone Strength and bone metabolism in child with chronic kidney disease Open
We investigated the effects of high VS. standard dose of vitamin D supplementation on kidney function and bone metabolism in children with chronic kidney disease (CKD). In all, 75 participants receive 2000 IU/D of vitamin D oral supplement…
View article: Genetic and functional analysis of two missense <i>DUOX2</i> mutations in congenital hypothyroidism and goiter
Genetic and functional analysis of two missense <i>DUOX2</i> mutations in congenital hypothyroidism and goiter Open
Mutations in the dual oxidase 2 gene (DUOX2) impair hydrogen peroxide (H2O2) production and cause dyshormonogenesis. In addition, these mutations have been implicated in autosomal recessive congenital hypothyroidism (CH) with goiter. In th…