Kunthi Pathmaraj
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View article: Theranostics Implementation: Opportunities and Challenges
Theranostics Implementation: Opportunities and Challenges Open
View article: Multidisciplinary Perspectives of Clinical Trials in Theranostics
Multidisciplinary Perspectives of Clinical Trials in Theranostics Open
Theranostics and clinical trials are driving the future of nuclear medicine and require a multidisciplinary approach to achieve the best possible care for the patient. Theranostics refers to using chemical compounds with similar diagnostic…
View article: The importance of quality management systems in nuclear medicine departments
The importance of quality management systems in nuclear medicine departments Open
Quality management systems (QMS) in nuclear medicine is an essential component of the Quality program and is instrumental in the safe delivery of a high standard clinical service. The IAEA QUANUM program is a nuclear medicine specific audi…
View article: A patient journey audit tool (PJAT) to assess quality indicators in a nuclear medicine service
A patient journey audit tool (PJAT) to assess quality indicators in a nuclear medicine service Open
View article: Using Q.Metrix to Evaluate Treatment Response to PRRT for Neuroendocrine Tumors of Gastroenteric or Pancreatic Origin
Using Q.Metrix to Evaluate Treatment Response to PRRT for Neuroendocrine Tumors of Gastroenteric or Pancreatic Origin Open
Objective: This study aimed to evaluate the treatment response to PRRT for neuroendocrine tumors of gastroenteric or pancreatic origin using Q.Metrix.
View article: Evaluation of 18F-FMISO PET and 18F-FDG PET Scans in Assessing the Therapeutic Response of Patients With Metastatic Colorectal Cancer Treated With Anti-Angiogenic Therapy
Evaluation of 18F-FMISO PET and 18F-FDG PET Scans in Assessing the Therapeutic Response of Patients With Metastatic Colorectal Cancer Treated With Anti-Angiogenic Therapy Open
Introduction Tumor hypoxia and angiogenesis are implicated in tumor growth and metastases, and anti-angiogenic therapies have an important role in treating patients with metastatic colorectal cancer. However, the prevalence of hypoxia has …
View article: Response Evaluation and Survival Prediction After PD-1 Immunotherapy in Patients with Non–Small Cell Lung Cancer: Comparison of Assessment Methods
Response Evaluation and Survival Prediction After PD-1 Immunotherapy in Patients with Non–Small Cell Lung Cancer: Comparison of Assessment Methods Open
Immunotherapy using programmed death-1 blockers is a promising modality for non-small cell lung cancer (NSCLC). Therefore, defining the most accurate response criteria for immunotherapy monitoring is of great importance in patient manageme…
View article: First clinical study of a pegylated diabody <sup>124</sup>I-labeled PEG-AVP0458 in patients with tumor-associated glycoprotein 72 positive cancers
First clinical study of a pegylated diabody <sup>124</sup>I-labeled PEG-AVP0458 in patients with tumor-associated glycoprotein 72 positive cancers Open
Through protein engineering and a novel pegylation strategy, a diabody specific to tumor-associated glycoprotein 72 (TAG-72) (PEG-AVP0458) has been created to optimize pharmacokinetics and bioavailability to tumor. We report the preclinica…
View article: ATIM-23. PRELIMINARY FINDINGS OF A PHASE I SAFETY AND BIOIMAGING TRIAL OF KB004 (IFABOTUZUMAB) IN PATIENTS WITH GLIOBLASTOMA
ATIM-23. PRELIMINARY FINDINGS OF A PHASE I SAFETY AND BIOIMAGING TRIAL OF KB004 (IFABOTUZUMAB) IN PATIENTS WITH GLIOBLASTOMA Open
Glioblastoma (GBM) is the most frequent and lethal primary brain neoplasm. EphA3 is a tumor restricted antigen expressed in 38–40% of GBM and 100% of the tumor vasculature. Ifabotuzumab is a non-fucosylated IgG1κ antibody targeting EphA3 r…
View article: Reproducibility and Repeatability of Semiquantitative <sup>18</sup>F-Fluorodihydrotestosterone Uptake Metrics in Castration-Resistant Prostate Cancer Metastases: A Prospective Multicenter Study
Reproducibility and Repeatability of Semiquantitative <sup>18</sup>F-Fluorodihydrotestosterone Uptake Metrics in Castration-Resistant Prostate Cancer Metastases: A Prospective Multicenter Study Open
18F-fluorodihydrotestosterone (18F-FDHT) is a radiolabeled analog of the androgen receptor's primary ligand that is currently being credentialed as a biomarker for prognosis, response, and pharmacodynamic effects of n…
View article: Fusion of positron emission tomography/computed tomography with magnetic resonance imaging reveals hamstring peritendonitis in polymyalgia rheumatica
Fusion of positron emission tomography/computed tomography with magnetic resonance imaging reveals hamstring peritendonitis in polymyalgia rheumatica Open
Australian New Zealand Clinical Trials Registry, http://www.anzctr.org.au, ACTRN1261400696695.
View article: Long-Acting Somatostatin Analog Therapy Differentially Alters<sup>68</sup>Ga-DOTATATE Uptake in Normal Tissues Compared with Primary Tumors and Metastatic Lesions
Long-Acting Somatostatin Analog Therapy Differentially Alters<sup>68</sup>Ga-DOTATATE Uptake in Normal Tissues Compared with Primary Tumors and Metastatic Lesions Open
Synthetic somatostatin analogs have been posed as a potential source of error in somatostatin receptor imaging through interference with tumor detection; however, experimental models and clinical studies have shown a complex mechanism of t…