Kunwei Peng
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The therapeutic promise of probiotic Bacteroides fragilis (BF839) in cancer immunotherapy Open
Background Overwhelming evidence suggests that the gut microbiota modulates tumor response to immune checkpoint inhibitors (ICIs). The probiotic Bacteroides fragilis (BF839) was extensively used in China to improve gut microbiota dysbiosis…
CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma Open
Hepatocellular carcinoma (HCC) responds poorly to standard chemotherapy or targeted therapy; hence, exploration for novel therapeutic targets is urgently needed. CEP192 protein is indispensable for centrosome amplification, which has been …
View article: The combined use of PD-1 antibodies and anti-angiogenic TKIs induces intractable thoracoabdominal wall ulcer in patients undergoing cryoablation for superficial metastases of hepatocellular carcinoma
The combined use of PD-1 antibodies and anti-angiogenic TKIs induces intractable thoracoabdominal wall ulcer in patients undergoing cryoablation for superficial metastases of hepatocellular carcinoma Open
Background: Percutaneous cryoablation has been widely used for local analgesia, especially for pain caused by superficial metastases. However, during the process of cryoablation for symptomatic superficial metastases of hepatocellular carc…
Optimal Surgery Type and Adjuvant Therapy for T1N0M0 Lung Large Cell Neuroendocrine Carcinoma Open
Background The appropriate treatment strategy for T1N0M0 lung large cell neuroendocrine carcinoma (LCNEC) was not well illustrated. We evaluated the efficacy of different surgery types and adjuvant therapy on patients with T1N0M0 LCNEC. Me…
The effect of adding concurrent chemotherapy to radiotherapy for stage II nasopharyngeal carcinoma with undetectable pretreatment Epstein-Barr virus DNA: Retrospective analysis with a large institutional-based cohort Open
Little is known about the value of adding concurrent chemotherapy (CC) to radiotherapy for stage II nasopharyngeal carcinoma (NPC) with undetectable (0 copies/mL) pretreatment Epstein-Barr Virus (EBV) DNA in the intensity-modulated radioth…
Previous Use of Anti-Vascular Endothelial Growth Factor Receptor Agents Decreases Efficacy of Fruquintinib in Metastatic Colorectal Cancer Refractory to Standard Therapies Open
Fruquintinib was an effective third-line therapy in mCRC with tolerable AEs. Efficacy of fruquintinib was decreased in patients with previous use of anti-VEGFR agents. NLR was an independent prognostic factor in PFS and OS in patients trea…
Dynamic variation and prognostic value of weight loss during radiotherapy in nasopharyngeal carcinoma: A large-scale cohort study Open
Background: We investigated the dynamic variation and prognostic value of weight loss among nasopharyngeal carcinoma (NPC) patients. Methods: 1149 newly diagnosed NPC patients receiving radical radiotherapy (RT) were retrospectively analyz…
NK homeobox 2.2 functions as tumor suppressor in colorectal cancer due to DNA methylation Open
Aim: The role of NK homeobox 2.2 (NKX2.2) in human colorectal cancer (CRC) remains to be unveiled. This study was designed to explore the epigenetic regulation and function of NKX2.2 in human CRC. Methods: The Cancer Genome Atlas (TCGA) an…
Comparisons of metastatic patterns of colorectal cancer among patients by age group: a population-based study Open
Population-based evaluations of the incidence of metastatic colorectal cancer at diagnosis among different age groups are lacking. Therefore, we investigated the effects of age at diagnosis on metastatic colorectal cancer and patients' pro…