Kurt Lehner
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View article: Electrocorticography during deep brain stimulation surgery for movement disorders; Single-center experience
Electrocorticography during deep brain stimulation surgery for movement disorders; Single-center experience Open
Background Electrocorticography (ECoG) can be used as an intraoperative research tool during deep brain stimulation (DBS) implantation procedures. Its application has contributed to understanding the neurophysiology of movement disorders a…
View article: Tethered Cord Prevalence among Patients with Prenatal or Postnatal Myelomeningocele Repair
Tethered Cord Prevalence among Patients with Prenatal or Postnatal Myelomeningocele Repair Open
Background: Myelomeningocele (MMC) is a severe form of spina bifida characterized by spinal cord extrusion into a cerebrospinal fluid (CSF) filled sac which may lead to lifelong disability. Repair of these lesions have classically occurred…
View article: Quantifying tethered spinal cord tension: Ultrasound elastography results from computational, cadaveric, and intraoperative first-in-human studies
Quantifying tethered spinal cord tension: Ultrasound elastography results from computational, cadaveric, and intraoperative first-in-human studies Open
Background Tension in the spinal cord is a trademark of tethered cord syndrome. Unfortunately, existing tests cannot quantify tension across the bulk of the cord, making the diagnostic evaluation of stretch ambiguous. A potential non-destr…
View article: Cerebrospinal Fluid biomarkers in pediatric brain tumors: A systematic review
Cerebrospinal Fluid biomarkers in pediatric brain tumors: A systematic review Open
View article: Spinal cord untethering and midline myelotomy for delayed, symptomatic post-traumatic syringomyelia due to retained ballistic fragments: case report
Spinal cord untethering and midline myelotomy for delayed, symptomatic post-traumatic syringomyelia due to retained ballistic fragments: case report Open
View article: Microsurgical Management of Complex Hypothalamic Hamartomas in the Era of Minimally Invasive Therapy: A Case Series and Narrative Review
Microsurgical Management of Complex Hypothalamic Hamartomas in the Era of Minimally Invasive Therapy: A Case Series and Narrative Review Open
IntroductionRecently, there has been a paradigm shift in the management of hypothalamic hamartoma (HH) from traditional microsurgical techniques to less invasive alternatives such as stereotactic radiosurgery and laser interstitial thermal…
View article: Quadrigeminal cistern cystic hemangioblastoma: A transcystic approach
Quadrigeminal cistern cystic hemangioblastoma: A transcystic approach Open
Introduction: Hemangioblastomas typically present throughout the neuroaxis, particularly within the cerebellum and spinal cord. A rare case of cystic hemangioblastoma within the quadrigeminal cistern is described. Case Report: A 18-year-ol…
View article: Prediction Models in Degenerative Spine Surgery: A Systematic Review
Prediction Models in Degenerative Spine Surgery: A Systematic Review Open
Study Design: Systematic review. Objectives: To review the existing literature of prediction models in degenerative spinal surgery. Methods: Review of PubMed/Medline and Embase databases was conducted to identify articles between January 1…
View article: Utility of prediction model score: a proposed tool to standardize the performance and generalizability of clinical predictive models based on systematic review
Utility of prediction model score: a proposed tool to standardize the performance and generalizability of clinical predictive models based on systematic review Open
OBJECTIVE The objective of this study was to evaluate the characteristics and performance of current prediction models in the fields of spine metastasis and degenerative spine disease to create a scoring system that allows direct compariso…
View article: Clinical utility of enhanced recovery after surgery pathways in pediatric spinal deformity surgery: systematic review of the literature
Clinical utility of enhanced recovery after surgery pathways in pediatric spinal deformity surgery: systematic review of the literature Open
OBJECTIVES More than 7500 children undergo surgery for scoliosis each year, at an estimated annual cost to the health system of $1.1 billion. There is significant interest among patients, parents, providers, and payors in identifying metho…
View article: Narrative Review of Predictive Analytics of Patient-Reported Outcomes in Adult Spinal Deformity Surgery
Narrative Review of Predictive Analytics of Patient-Reported Outcomes in Adult Spinal Deformity Surgery Open
Study Design: Narrative review Objective: Decision making in surgery for adult spinal deformity (ASD) is complex due to the multifactorial etiology, numerous surgical options, and influence of multiple medical and psychosocial factors on p…
View article: To operate, or not to operate? Narrative review of the role of survival predictors in patient selection for operative management of patients with metastatic spine disease
To operate, or not to operate? Narrative review of the role of survival predictors in patient selection for operative management of patients with metastatic spine disease Open
Accurate prediction of patient survival is an essential component of the preoperative evaluation of patients with spinal metastases. Over the past quarter of a century, a number of predictors have been developed, although none have been ac…
View article: Validation of corpus callosotomy after laser interstitial thermal therapy: a multimodal approach
Validation of corpus callosotomy after laser interstitial thermal therapy: a multimodal approach Open
Objective Disconnection of the cerebral hemispheres by corpus callosotomy (CC) is an established means to palliate refractory generalized epilepsy. Laser interstitial thermal therapy (LITT) is gaining acceptance as a minimally invasive app…
View article: A Dual Approach for the Management of Complex Craniovertebral Junction Abnormalities: Endoscopic Endonasal Odontoidectomy and Posterior Decompression with Fusion
A Dual Approach for the Management of Complex Craniovertebral Junction Abnormalities: Endoscopic Endonasal Odontoidectomy and Posterior Decompression with Fusion Open
View article: Skull Base 3D Modeling of Rigid Buttress for Gasket-Seal Closure Using Operative Endoscopic Imaging: Cadaveric Feasibility
Skull Base 3D Modeling of Rigid Buttress for Gasket-Seal Closure Using Operative Endoscopic Imaging: Cadaveric Feasibility Open
Surgical defect closure following endonasal transsphenoidal tumor resection is a critical component of procedural success. Three-dimensional (3D) modeling of relevant skull base anatomy during resection can potentially facilitate design of…
View article: Endoscopic endonasal resection of epidermoid cysts involving the ventral cranial base
Endoscopic endonasal resection of epidermoid cysts involving the ventral cranial base Open
OBJECTIVE Epidermoid cysts (ECs) commonly extend to involve the ventral cisterns of the cranial base. When present, symptoms arise due to progressive mass effect on the brainstem and adjacent cranial nerves. Historically, a variety of open…
View article: American views of Sir Victor Horsley in the era of Cushing
American views of Sir Victor Horsley in the era of Cushing Open
Sir Victor Horsley was a pioneering British neurosurgeon known for his numerous neurosurgical, scientific, and sociopolitical contributions. Although word of these surgical and scientific achievements quickly spread throughout Europe and N…
View article: Outcomes following Expanded Endonasal Resection of Epidermoid Tumors Involving the Cranial Base: Case Series of Seven Patients
Outcomes following Expanded Endonasal Resection of Epidermoid Tumors Involving the Cranial Base: Case Series of Seven Patients Open
Objective Epidermoid cysts frequently affect the cerebellopontine angle, suprasellar cistern, and cranial base. It is common for these lesions to intimately involve multiple cranial nerves and vascular structures—sometimes with dense adher…
View article: Skull Base 3D Modeling and Rapid Prototyping of Rigid Buttress for Gasket-Seal Closure Using Operative Endoscopic Imaging: Cadaveric Feasibility
Skull Base 3D Modeling and Rapid Prototyping of Rigid Buttress for Gasket-Seal Closure Using Operative Endoscopic Imaging: Cadaveric Feasibility Open
Background Skull base reconstruction following endonasal transsphenoidal tumor resection is a focus of active technical development that has seen steady evolution of multiple approaches to surgical defect closure over the past decade. A pr…
View article: Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs
Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs Open
View article: Reinforcing and neurochemical effects of the “bath salts” constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats
Reinforcing and neurochemical effects of the “bath salts” constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats Open