Kwuntida Uthaisar Kotepui
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View article: A systematic review and meta-analysis of Plasmodium infections and erythrocyte sedimentation rate in relation to disease severity
A systematic review and meta-analysis of Plasmodium infections and erythrocyte sedimentation rate in relation to disease severity Open
The findings of this study indicate that elevated ESR is frequently reported in malaria patients and may be more pronounced in severe cases. However, the very high between-study heterogeneity and the presence of publication bias limit conf…
View article: A Systematic Review and Meta-Analysis of MIP-1α and MIP-1β Chemokines in Malaria in Relation to Disease Severity
A Systematic Review and Meta-Analysis of MIP-1α and MIP-1β Chemokines in Malaria in Relation to Disease Severity Open
Background and Objectives: Macrophage inflammatory protein-1α (MIP-1α) and MIP-1β act as signaling molecules that recruit immune cells to sites of infection and inflammation. This study aimed to synthesize evidence on blood levels of MIP-1…
View article: Elevations in D-dimer levels in patients with Plasmodium infections: a systematic review and meta-analysis
Elevations in D-dimer levels in patients with Plasmodium infections: a systematic review and meta-analysis Open
D-dimer, a byproduct of cross-linked fibrin degradation, arises during the fibrinolysis process, breaking down blood clots in circulation. This systematic review and meta-analysis aimed to synthesize evidence of D-dimer alteration in peopl…
View article: Prevalence and subtype distribution of <i>Blastocystis</i> infections among community participants in Thailand: a systematic review and meta-analysis
Prevalence and subtype distribution of <i>Blastocystis</i> infections among community participants in Thailand: a systematic review and meta-analysis Open
A comprehensive understanding of the prevalence and subtype distribution of Blastocystis infections among community participants in Thailand is essential to inform targeted public health interventions. This systematic review and meta-analy…
View article: A systematic review of circulating IP-10/CXCL10 in patients with Plasmodium infections in relation to disease severity
A systematic review of circulating IP-10/CXCL10 in patients with Plasmodium infections in relation to disease severity Open
Interferon γ-induced protein 10 kDa (IP-10) or C–X–C motif chemokine 10 (CXCL10) is produced and secreted from specific leukocytes such as neutrophils, eosinophils, and monocytes, which play key roles in the immune response to Plasmodium i…
View article: A systematic review and meta-analysis of blood level of MCP-1/CCL-2 in severe and uncomplicated malaria
A systematic review and meta-analysis of blood level of MCP-1/CCL-2 in severe and uncomplicated malaria Open
Monocyte chemoattractant protein-1 (MCP-1) or C-C Motif Chemokine Ligand 2 (CCL-2) is a key chemokine implicated in the inflammatory response to malaria. The objective of the study was to synthesize the evidence on variations in MCP-1/CCL-…
View article: Association between RANTES/CCL5 levels with Plasmodium infections and malaria severity: a systematic review
Association between RANTES/CCL5 levels with Plasmodium infections and malaria severity: a systematic review Open
Background Malaria continues to be a significant global health concern, and developing effective therapeutic strategies requires an understanding of the immune response to the disease. This systematic review synthesized the current body of…
View article: Total antioxidant status levels in malaria: a systematic review and meta-analysis
Total antioxidant status levels in malaria: a systematic review and meta-analysis Open
Background Malaria, a severe health threat, significantly affects total antioxidant status (TAS) levels, leading to considerable oxidative stress. This systematic review and meta-analysis aimed to delineate differences in TAS levels betwee…
View article: Albumin levels in malaria patients: a systematic review and meta-analysis of their association with disease severity
Albumin levels in malaria patients: a systematic review and meta-analysis of their association with disease severity Open
Albumin, a key protein in human blood plasma, has been linked to various health conditions. However, its association with malaria, particularly in assessing disease severity, remains inadequately understood. This comprehensive systematic r…
View article: Alteration of prothrombin time in Plasmodium falciparum and Plasmodium vivax infections with different levels of severity: a systematic review and meta-analysis
Alteration of prothrombin time in Plasmodium falciparum and Plasmodium vivax infections with different levels of severity: a systematic review and meta-analysis Open
Malaria infection leads to hematological abnormalities, including deranged prothrombin time (PT). Given the inconsistent findings regarding PT in malaria across different severities and between Plasmodium falciparum and P. vivax , this stu…
View article: A Systematic Review and Meta-Analysis Exploring Variations in Copper Levels between Individuals with Malaria and Uninfected Controls
A Systematic Review and Meta-Analysis Exploring Variations in Copper Levels between Individuals with Malaria and Uninfected Controls Open
Micronutrient insufficiency has been implicated in malaria pathogenesis. However, the role of copper in malaria remains inconclusive. This study aimed to investigate the association between copper levels and malaria pathogenesis, providing…
View article: Regional and Age-Related Variations in Blood Calcium Levels among Patients with Plasmodium falciparum and P. vivax malaria: A Systematic Review and Meta-Analysis
Regional and Age-Related Variations in Blood Calcium Levels among Patients with Plasmodium falciparum and P. vivax malaria: A Systematic Review and Meta-Analysis Open
Despite several studies examining the relationship between calcium levels and malaria, inconsistencies and varied results remain in the literature. This study aimed to synthesize the evidence on the association between blood calcium levels…
View article: Association between NDRG1 protein expression and aggressive features of breast cancer: a systematic review and meta-analysis
Association between NDRG1 protein expression and aggressive features of breast cancer: a systematic review and meta-analysis Open
Background N-myc downstream-regulated gene-1 (NDRG1) is well-described as a potent metastasis suppressor, but its role in human breast cancer remains controversial and unclear. Therefore, the present study utilized a systematic review and …
View article: Association between Plasmodium Infection and Nitric Oxide Levels: A Systematic Review and Meta-Analysis
Association between Plasmodium Infection and Nitric Oxide Levels: A Systematic Review and Meta-Analysis Open
Nitric oxide (NO) has been implicated in the pathology of malaria. This systematic review and meta-analysis describe the association between NO levels and malaria. Embase, Ovid, PubMed, Scopus, and Google Scholar were searched to identify …
View article: Association of uric acid levels with severity of Plasmodium infections: a systematic review and meta-analysis
Association of uric acid levels with severity of Plasmodium infections: a systematic review and meta-analysis Open
Elevated uric acid (UA) levels have been reported in malaria patients and are particularly prominent in severe malaria cases. This study aims to synthesize the difference in UA levels between malaria patients and uninfected controls, and b…
View article: Differences in catalase levels between malaria-infected individuals and uninfected controls: a systematic review and meta-analysis
Differences in catalase levels between malaria-infected individuals and uninfected controls: a systematic review and meta-analysis Open
Inconsistent catalase (CAT) research necessitates a comprehensive review of CAT levels among patients with malaria to achieve better therapeutic strategies. This study aimed to systematically review and meta-analyze available literature on…
View article: The Association between Malaria and β-Carotene Levels: A Systematic Review and Meta-Analysis
The Association between Malaria and β-Carotene Levels: A Systematic Review and Meta-Analysis Open
Background: β-Carotene, which is a prominent carotenoid with notable antioxidant properties, may play a role in countering the oxidative stresses induced by malaria. The association between β-carotene levels and malaria is not yet fully un…
View article: Effect of Malaria on Blood Levels of Vitamin E: A Systematic Review and Meta-Analysis
Effect of Malaria on Blood Levels of Vitamin E: A Systematic Review and Meta-Analysis Open
Vitamin E has an antioxidant property and is associated with protection against malaria. The current study used systematic review and meta-analysis approaches examining the variance in blood levels of vitamin E in malaria patients as compa…