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View article: Lacosamide-Induced Bullous Pemphigoid
Lacosamide-Induced Bullous Pemphigoid Open
Drug-induced bullous pemphigoid (DIBP) is a rare condition commonly associated with polypharmacy. Unlike several other antiepileptic drugs, lacosamide has not been linked previously to the development of bullous pemphigoid (BP). We report …
View article: A Systematic Review and Meta-Analysis on the Role of Somatostatin Therapy in Non-Variceal Gastrointestinal Bleeding
A Systematic Review and Meta-Analysis on the Role of Somatostatin Therapy in Non-Variceal Gastrointestinal Bleeding Open
Background and Aims: Non-variceal upper gastrointestinal bleeding (NVUGIB) is a common cause of hospitalizations, with proton pump inhibitors (PPIs) being the mainstay treatment. However, there is a lack of high-level evidence to show if a…
View article: Effect of Cystic Fibrosis Transmembrane Conductance Regulator Modulators on Liver Enzymes Among Patients With Cystic Fibrosis: A Systematic Review and Meta-Analysis
Effect of Cystic Fibrosis Transmembrane Conductance Regulator Modulators on Liver Enzymes Among Patients With Cystic Fibrosis: A Systematic Review and Meta-Analysis Open
View article: More Than Pyelonephritis: A Rare Case of a Perinephric Abscess Secondary to Post-ERCP Duodenal Perforation
More Than Pyelonephritis: A Rare Case of a Perinephric Abscess Secondary to Post-ERCP Duodenal Perforation Open
This case discusses the complication of duodenal perforation secondary to endoscopic retroperitoneal cholangiopancreatography (ERCP) with development of a retroperitoneal abscess. The patient was a 35-year-old woman who presented 1 week fo…
View article: Fecal Microbiota Transplantation for Chronic Pouchitis: A Systematic Review and Meta-Analysis
Fecal Microbiota Transplantation for Chronic Pouchitis: A Systematic Review and Meta-Analysis Open
Pouchitis is a common complication after ileal-pouch anal anastomosis in patients with medically refractory ulcerative colitis. There has been a lack of high-level evidence focusing on the safety and efficacy outcomes of fecal microbiota t…
View article: Efficacy and safety of over-the-scope endoscopic suturing device for closure of defects after endoscopic submucosal dissection: a systematic review and meta-analysis
Efficacy and safety of over-the-scope endoscopic suturing device for closure of defects after endoscopic submucosal dissection: a systematic review and meta-analysis Open
View article: Clostridioides difficile Infection-Related Hepatic Abscess: A Review of the Literature
Clostridioides difficile Infection-Related Hepatic Abscess: A Review of the Literature Open
Hepatic abscesses (HAs) are suppurative cavities caused by the infiltration of liver parenchyma by microbes. The etiology of HAs can include biliary disease, intra-abdominal infections, bile duct ischemia following pancreaticoduodenectomy,…
View article: From guts to skin; unmasking risk factors of pyoderma gangrenosum among Crohn’s disease patients
From guts to skin; unmasking risk factors of pyoderma gangrenosum among Crohn’s disease patients Open
View article: A Case of Pancreatic Schwannoma, a Rare and Often-Misdiagnosed Entity
A Case of Pancreatic Schwannoma, a Rare and Often-Misdiagnosed Entity Open
Pancreatic schwannomas are an extremely rare form of schwannoma that can undergo malignant transformation. Patients can be asymptomatic or have nonspecific symptoms. Imaging also can be nonspecific. Biopsy with immunohistochemical staining…
View article: The Use of Fecal Microbiota Transplant in Overcoming and Modulating Resistance to Anti-PD-1 Therapy in Patients with Skin Cancer
The Use of Fecal Microbiota Transplant in Overcoming and Modulating Resistance to Anti-PD-1 Therapy in Patients with Skin Cancer Open
While immune checkpoint inhibitors have evolved into the standard of care for advanced melanoma, 40–50% of melanoma cases progress while on therapies. The relationship between bacterium and carcinogenesis is well founded, such as in H. pyl…
View article: Incidence and risk factors of Clostridioides difficile infection in liver transplant recipients: A comprehensive literature review
Incidence and risk factors of Clostridioides difficile infection in liver transplant recipients: A comprehensive literature review Open
INTRODUCTION Clostridioides difficile infection (CDI) has recently emerged as a cause of rising morbidity and mortality in hospitalized patients in North America.1 CDI is seen in 3%–7% of liver transplant recipients (LTRs) and is noted to …
View article: Metabolic dysfunction–associated steatotic liver disease and cardiovascular disease
Metabolic dysfunction–associated steatotic liver disease and cardiovascular disease Open
INTRODUCTION According to recent estimates, steatotic liver disease affects about 30% of the global population, and there has been a significant 16% increase in cases between 1991 and 2019.1 In November 2023, the American Association for t…
View article: The Potential Role of Fecal Microbiota Transplant in the Reversal or Stabilization of Multiple Sclerosis Symptoms: A Literature Review on Efficacy and Safety
The Potential Role of Fecal Microbiota Transplant in the Reversal or Stabilization of Multiple Sclerosis Symptoms: A Literature Review on Efficacy and Safety Open
Multiple sclerosis (MS) affects millions of people worldwide, and recent data have identified the potential role of the gut microbiome in inducing autoimmunity in MS patients. To investigate the potential of fecal microbiota transplant (FM…
View article: The Potential Role of Fecal Microbiota Transplantation in Parkinson’s Disease: A Systematic Literature Review
The Potential Role of Fecal Microbiota Transplantation in Parkinson’s Disease: A Systematic Literature Review Open
Background and Aims: Parkinson’s disease (PD) is a multifaceted disease that can cause symptoms in multiple body systems, including the gastrointestinal (GI) tract. Fecal microbiota transplantation (FMT) is a proposed treatment to address …
View article: Efficacy and safety of submucosal tunneling endoscopic resection for subepithelial tumors in the upper GI tract: a systematic review and meta-analysis of >2900 patients
Efficacy and safety of submucosal tunneling endoscopic resection for subepithelial tumors in the upper GI tract: a systematic review and meta-analysis of >2900 patients Open
Background and aims Submucosal tunnel endoscopic resection (STER) is an emerging therapeutic tool that allows direct visualization and resection of submucosal tunneling endoscopic resection (SETs) from the upper GI tract while maintaining …
View article: A Rare Case of Hereditary Hemochromatosis Presenting With Porphyria Cutanea Tarda
A Rare Case of Hereditary Hemochromatosis Presenting With Porphyria Cutanea Tarda Open
View article: Noninvasive tests in the evaluation of nonalcoholic fatty liver disease: A review
Noninvasive tests in the evaluation of nonalcoholic fatty liver disease: A review Open
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View article: Efficacy of Fecal Microbiota Transplant on Neuromotor and Gastrointestinal Symptoms in Parkinson's Disease: A Systematic Review
Efficacy of Fecal Microbiota Transplant on Neuromotor and Gastrointestinal Symptoms in Parkinson's Disease: A Systematic Review Open
A systematic review completed to evaluate the efficacy of fecal microbiota transplant in the treatment of neuromotor and/or gastrointestinal symptoms of Parkinson's disease patients.
View article: Safety and Efficacy of Fecal Microbiota Transplantation in Treatment of Inflammatory Bowel Disease in the Pediatric Population: A Systematic Review and Meta-Analysis
Safety and Efficacy of Fecal Microbiota Transplantation in Treatment of Inflammatory Bowel Disease in the Pediatric Population: A Systematic Review and Meta-Analysis Open
Background and Aims: Fecal microbiota transplantation (FMT) has been increasingly studied in the inflammatory bowel disease (IBD) population. However, most studies have focused on the adult population, and the safety and efficacy of FMT in…
View article: Cardiac Anesthesia Intraoperative Interpretation Accuracy of Transesophageal Echocardiograms: A Review of the Current Literature and Meta-Analysis
Cardiac Anesthesia Intraoperative Interpretation Accuracy of Transesophageal Echocardiograms: A Review of the Current Literature and Meta-Analysis Open
Based on these studies, cardiac anesthesiologists are shown to interpret TEEs similarly to that of primary echocardiographers. At this time, there is no gold standard to evaluate the accuracy of TEE readings. One way to address this is to …
View article: A Comparative Study of Acute Alcoholic Hepatitis vs. Non-Alcoholic Hepatitis Patients from a Cohort with Chronic Alcohol Dependence
A Comparative Study of Acute Alcoholic Hepatitis vs. Non-Alcoholic Hepatitis Patients from a Cohort with Chronic Alcohol Dependence Open
The rate of alcoholic hepatitis (AH) has risen in recent years. AH can cause as much as 40–50% mortality in severe cases. Successful abstinence has been the only therapy associated with long-term survival in patients with AH. Thus, it is c…
View article: Efficacy of Fecal Microbiota Transplant on Behavioral and Gastrointestinal Symptoms in Pediatric Autism: A Systematic Review
Efficacy of Fecal Microbiota Transplant on Behavioral and Gastrointestinal Symptoms in Pediatric Autism: A Systematic Review Open
Background and Aims: There is a high prevalence of gastrointestinal-related (GI) symptoms among children with autism spectrum disorder (ASD), which is associated with the severity of behavioral symptoms. Fecal microbiota transplantation (F…
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View article: A Rare Case of Methotrexate-Induced Gastric Ulcer
A Rare Case of Methotrexate-Induced Gastric Ulcer Open
View article: Factors associated with improved outcome of inhaled corticosteroid use in COVID-19: A single institutional study
Factors associated with improved outcome of inhaled corticosteroid use in COVID-19: A single institutional study Open
Asthmatics seem less prone to adverse outcomes in coronavirus disease 2019 (COVID-19) and some data shows that inhaled corticosteroids (ICS) are protective. We gathered data on anecdotal ICS and outcomes of patients hospitalized with COVID…
View article: Efficacy and Safety of Fecal Microbiota Transplantation in Treatment of Clostridioides difficile Infection among Pediatric Patients: A Systematic Review and Meta-Analysis
Efficacy and Safety of Fecal Microbiota Transplantation in Treatment of Clostridioides difficile Infection among Pediatric Patients: A Systematic Review and Meta-Analysis Open
Background and Aims: Cases of Clostridioides difficile infection have been rising among the pediatric and adolescent population. Fecal microbiota transplantation (FMT) has emerged as an alternative therapy for recurrent C. difficile infect…
View article: Short-term outcomes of patients transferred from non-acute care centers with sick sinus syndrome
Short-term outcomes of patients transferred from non-acute care centers with sick sinus syndrome Open
Background Non-acute care centers, such as nursing homes and urgent care clinics, are a staple of healthcare systems worldwide. The short-term prognostic outcomes of patients transferred from a non-acute care center to an acute healthcare …
View article: Gastric Siderosis Due to Oral Ferrous Sulfate Supplements
Gastric Siderosis Due to Oral Ferrous Sulfate Supplements Open
Gastric siderosis is the deposition of excess amount of iron from oral ferrous sulfate supplements to the gastric mucosa. It is an often overlooked entity in the literature and can be related to symptoms such as dyspepsia, nausea, and mele…
View article: Fecal Microbiota Transplantation in Decompensated Cirrhosis: A Systematic Review on Safety and Efficacy
Fecal Microbiota Transplantation in Decompensated Cirrhosis: A Systematic Review on Safety and Efficacy Open
Background and Aims: Due to increasing knowledge of the “gut–liver axis”, there has been growing interest regarding the use of fecal microbiota transplant in the management of chronic liver disease. There are limited data available and cur…
View article: Intrapulmonary Gallstones and Pleuro-Biliary Fistula Formation Due to Complication From Prior Cholecystectomy: A Case Report and Literature Review
Intrapulmonary Gallstones and Pleuro-Biliary Fistula Formation Due to Complication From Prior Cholecystectomy: A Case Report and Literature Review Open
Intrapulmonary gallstones and the formation of pleuro-biliary fistula is a rare complication of laparoscopic cholecystectomy. The stones are most commonly found in the right lower lobe of the lungs. The symptoms tend to be insidious in nat…