Kyle A. Weant
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View article: Chronotherapeutic considerations of benzodiazepine administration for agitation management in the emergency department
Chronotherapeutic considerations of benzodiazepine administration for agitation management in the emergency department Open
Objective Agitation in the emergency department (ED) affects up to 2.6% of encounters, posing significant risks to patients and caregivers. This review investigates the impact of circadian rhythms on benzodiazepine (BZD) pharmacokinetics a…
View article: 3-Factor prothrombin complex concentrate versus 4-factor prothrombin complex concentrate for the reversal of oral factor Xa inhibitors
3-Factor prothrombin complex concentrate versus 4-factor prothrombin complex concentrate for the reversal of oral factor Xa inhibitors Open
View article: Safety and efficacy of fixed versus variable-dose prothrombin complex concentrate for emergent reversal of vitamin K antagonists: A systematic review and meta-analysis
Safety and efficacy of fixed versus variable-dose prothrombin complex concentrate for emergent reversal of vitamin K antagonists: A systematic review and meta-analysis Open
View article: The Cents of the Dosage Cap in Patients Greater than 100 Kilograms Receiving N-Acetylcysteine for Acetaminophen Toxicity
The Cents of the Dosage Cap in Patients Greater than 100 Kilograms Receiving N-Acetylcysteine for Acetaminophen Toxicity Open
View article: Latex Allergy Alerts in the Age of CPOE: Assessing the Risk From Injectable Medications
Latex Allergy Alerts in the Age of CPOE: Assessing the Risk From Injectable Medications Open
View article: Risk Factors for Antibiotic Resistant Urinary Pathogens in Patients Discharged From the Emergency Department
Risk Factors for Antibiotic Resistant Urinary Pathogens in Patients Discharged From the Emergency Department Open
Purpose: Urinary tract infections (UTIs) are one of the most common indications for antimicrobial use in the emergency department (ED). Appropriate empiric selection is crucial to ensure optimal care while limiting broad-spectrum antibioti…
View article: Evaluation of Dosing Strategies of N-acetylcysteine for Acetaminophen Toxicity in Patients Greater than 100 Kilograms: Should the Dosage Cap Be Used?
Evaluation of Dosing Strategies of N-acetylcysteine for Acetaminophen Toxicity in Patients Greater than 100 Kilograms: Should the Dosage Cap Be Used? Open
View article: Characterization of Emergency Department Rabies Post-Exposure Prophylaxis Procedures with an Infectious Diseases Clinic Referral Process
Characterization of Emergency Department Rabies Post-Exposure Prophylaxis Procedures with an Infectious Diseases Clinic Referral Process Open
Purpose: Rabies post-exposure prophylaxis (rPEP) in the emergency department (ED) is associated with high costs, complicated administration protocols, and a time-sensitive vaccination series that often requires ED follow-up visits for subs…
View article: Online Participation in a Pharmacy Residency Research Certificate Program
Online Participation in a Pharmacy Residency Research Certificate Program Open
View article: Development of a Pharmacy Residency Research Certificate Program
Development of a Pharmacy Residency Research Certificate Program Open
Background: Similar to teaching certificate programs, which have been incorporated in many pharmacy residencies to improve teaching skills, resident research certificate programs could provide residents with more exposure to biostatistics …
View article: Compliance and Related Outcomes of Prophylactic Antibiotics in Traumatic Open Fractures
Compliance and Related Outcomes of Prophylactic Antibiotics in Traumatic Open Fractures Open
Purpose: Prophylactic antibiotic therapy is a standard of care for patients who present with open fractures due to the risk of infectious complications. This study was conducted to characterize the use of initial prophylactic antibiotic us…
View article: Impact of an Advanced Pharmacy Practice Experience Student-Run “Meds 2 Beds” and Discharge Counseling Program on Quality of Care
Impact of an Advanced Pharmacy Practice Experience Student-Run “Meds 2 Beds” and Discharge Counseling Program on Quality of Care Open
Purpose: As health care progresses toward pay for performance reimbursement models and focus is placed on the patient as a consumer, health care systems must adapt by initiating new programs and services. This institution responded by impl…
View article: Implications of Statin Use on Vasopressor Therapy in the Setting of Septic Shock
Implications of Statin Use on Vasopressor Therapy in the Setting of Septic Shock Open
Background: Pleiotropic anti-inflammatory and immunomodulatory effects of statins have been associated with improved outcomes in the critically ill population. Objective: To evaluate the implications of prior statin use on the duration of …
View article: Modified two step N-acetylcysteine dosing regimen for the treatment of acetaminophen overdose a safe alternative
Modified two step N-acetylcysteine dosing regimen for the treatment of acetaminophen overdose a safe alternative Open
Intravenous N-acetylcysteine (IV NAC) is currently the approved treatment for acetaminophen (APAP) overdose with a three-step regimen totaling 300 mg/kg over 21 hours. Due to the complexity of this regimen, some institutions have used simp…
View article: Dosing of Appropriate Antibiotics and Time to Administration of First Doses in the Pediatric Emergency Department
Dosing of Appropriate Antibiotics and Time to Administration of First Doses in the Pediatric Emergency Department Open
OBJECTIVES: Emergency department (ED) providers are faced with the challenge of diagnosing and treating patients in a timely fashion given many obstacles including limited patient information, complex disease states, and high patient turno…