Explanipedia

Thoracic intradural extramedullary solitary fibrous tumor: A case report and review of the literature Open

Chinelo Onyiah, Stephen Jaffee, Nathan Esplin, Kymberly A. Gyure, Danyal Quraishi , et al. · 2025

Background: Solitary fibrous tumors (SFTs) are rare neoplasms of mesenchymal origin that is thought to arise from pericapillary (Zimmermann) cells. They most commonly occur in the visceral pleura. Here, a 79-year-old male presented with my…

Rare osseous mastoid invasion of secondary gliosarcoma: illustrative case Open

Mokshal H. Porwal, Dallas E. Kramer, Smrithi Chidambaram, Jae-Hyeok Chang, Kymberly A. Gyure , et al. · 2025

BACKGROUND Gliosarcomas are rare isocitratedehydrogenase –wildtype glioblastomas characterized by their glial and sacromatous components. A gliosarcoma is primary if the tumor arose de novo and secondary if the tumor arose from a previous …

Diffuse glioneuronal tumor in Lynch syndrome: illustrative case Open

Stephen Jaffee, Trent Kite, Kymberly A. Gyure, John Herbst, Stephen Karlovits , et al. · 2025

BACKGROUND Lynch syndrome (LS) is an autosomal dominant disorder caused by impaired DNA mismatch repair during the DNA replication process. The condition increases the risk of gastrointestinal and gynecological cancers as well as oligodend…

Trigeminal nerve hemangioblastoma in the setting of undiagnosed von Hippel–Lindau disease: illustrative case Open

Nisha Busch, Alejandro Matos Cruz, John Herbst, Kymberly A. Gyure, Rodney E. Wegner , et al. · 2024

BACKGROUND Von Hippel–Lindau disease (VHL) is an autosomal dominant tumor predisposition syndrome caused by mutations in the VHL gene. Patients with VHL are predisposed to developing numerous neoplasms, including central nervous system hem…

Transmission of yellow fever vaccine virus through blood transfusion and organ transplantation in the USA in 2021: report of an investigation Open

Carolyn V. Gould, Rebecca J. Free, Julu Bhatnagar, Raymond Soto, Tricia Royer , et al. · 2023

US Centers for Disease Control and Prevention (CDC), the Biomedical Advanced Research and Development Authority, and the CDC Epidemiology and Laboratory Capacity Cooperative Agreement for Infectious Diseases.

Rare case of extracranial chordoid meningioma adjacent to the carotid sheath: illustrative case Open

Seung Won Jeong, Michael Moran, Shahed Elhamdani, Dorian Kusyk, Xu Chen , et al. · 2023

BACKGROUND Chordoid meningioma is a rare World Health Organization (WHO) grade 2 variant of meningioma with histological features resembling those of a chordoma. This tumor type is known for having an aggressive clinical course with a prop…

Ocular Human Papillomavirus Infections Open

Mehenaz Hanbazazh, Kymberly A. Gyure · 2018

Context.— Human papillomavirus (HPV) has a well-known role in the pathogenesis of squamous cell carcinoma and precursor lesions of the cervix, anogenital region, and head and neck, but its role in the development of squamous neoplasms of t…

Glioblastoma Survival Outcomes at a Tertiary Hospital in Appalachia: Factors Impacting the Survival of Patients Following Implementation of the Stupp Protocol Open

Ogaga Urhie, Ryan Turner, Brandon Lucke‐Wold, Walid Radwan, Janice Ahn , et al. · 2018

Completed Suicide in An Autopsy-Confirmed Case of Early Onset Alzheimer’s Disease Open

Jennifer Wiener Hartzell, Richard S. Geary, Kymberly A. Gyure, Venkata Ravi Chivukula, Marc W. Haut · 2018

We report a case of a 57-year-old male with clinically diagnosed and autopsy-confirmed early onset Alzheimer's disease who completed suicide by gunshot wound to the chest. This case has several unique aspects that have not been discussed i…

The first American cancer patient to receive dicycloplatin chemotherapy: A case report Open

JJ Yu, Salkini MW, Shunchang Jiao, Tiffany Hogan, Yanjie Guo , et al. · 2017

Dicycloplatin (DCP), an effective platinum drug, was developed in China and approved by Chinese FDA in 2012.Its side effects are more bearable than those of cisplatin and carboplatin.The bladder cancer patient presented here was a 65-year-…

Follicular lymphoma presenting as scalp mass deformity: Case Report and Review of the literature Open

Divine C. Nwafor, Walid Radwan, Brandon Lucke‐Wold, William Underwood, Kymberly A. Gyure , et al. · 2017

Lymphoma presenting as a scalp mass is a rare but serious medical condition mandating aggressive treatment and neurosurgical intervention. We report a case of 53-year-old male who presented with a large right sided frontal scalp mass and a…

Neurosarcoidosis: unusual presentations and considerations for diagnosis and management Open

Walid Radwan, Brandon Lucke‐Wold, Ibrahim Ahmed Robadi, Kymberly A. Gyure, Thomas Duval Roberts , et al. · 2016

Background Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous s…

Lipomatous meningioma: Case report and review of the literature Open

Walid Radwan, Brandon Lucke‐Wold, Cletus Cheyuo, Janice Ahn, Kymberly A. Gyure , et al. · 2016

Lipomatous meningiomas are a very rare form of brain meningiomas consisting of fat accumulation within the tumor. Magnetic resonance imaging (MRI) or computerized tomographic (CT) imaging can be utilized to visualize the fat accumulations,…

Giant calvarial intraosseous angiolipoma: a case report and review of the literature Open

Rahul Singh, Darnell T. Josiah, Ryan C. Turner, David E. Cantu-Durand, H. James Williams , et al. · 2016

Intraosseous angiolipomas are very rare tumors occurring most commonly in the ribs and mandible. Only two cases with intracranial involvement have been reported in the literature. We report a case of a giant calvarial angiolipoma and its s…

A Review of Vascular Abnormalities of the Spine. Open

Rahul Singh, Brandon Lucke‐Wold, Kymberly A. Gyure, SoHyun Boo · 2016

Patients with spinal vascular lesions present with unique symptoms and have important anatomical and physiologic changes that must be considered prior to treatment. In this mini-review, we provide an overview of normal spinal vascular anat…

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