Kyoung-Dong Kim
YOU?
Author Swipe
View article: Unique Role of Med8 in Ace2 Recruitment and Target Gene Expression in <i>Schizosaccharomyces pombe</i>
Unique Role of Med8 in Ace2 Recruitment and Target Gene Expression in <i>Schizosaccharomyces pombe</i> Open
The Mediator, an essential RNA polymerase II coactivator, is a conserved multi-subunit protein complex present in organisms ranging from yeast to humans. Although its role in transcription is well-characterized, the distinct functions of i…
View article: Acetic acid produced by <i>Staphylococcus epidermidis</i> remodels chromatin architecture and suppresses gene expression in <i>Malassezia restricta</i>
Acetic acid produced by <i>Staphylococcus epidermidis</i> remodels chromatin architecture and suppresses gene expression in <i>Malassezia restricta</i> Open
The skin microbiome is composed of diverse microbial communities that engage in interkingdom interactions, influencing host physiology and microbial balance. Although Malassezia restricta and Staphylococcus epidermidis are codominant membe…
View article: Metal ion homeostasis regulates condensin-dependent chromatin architecture and chromosome segregation in Schizosaccharomyces pombe
Metal ion homeostasis regulates condensin-dependent chromatin architecture and chromosome segregation in Schizosaccharomyces pombe Open
Condensin plays a central role in mitotic chromosome organization and segregation by mediating long-range chromatin interactions. However, the extent to which cellular metabolic status influences condensin function remains unclear. To gain…
View article: Multifunctional and endogenous stimuli-responsive vinblastine sulfate/manganese dioxide nanodrugs for enhancing chemotherapeutic efficacy against hypoxic tumors
Multifunctional and endogenous stimuli-responsive vinblastine sulfate/manganese dioxide nanodrugs for enhancing chemotherapeutic efficacy against hypoxic tumors Open
Several solid tumors contain large hypoxic regions, diminishing drug responses and resulting in limited therapeutic outcomes. Vinblastine sulfate (VBL) targets the tubulin molecule, causing microtubule depolymerization and inducing mitotic…
View article: Viral remodeling of the 4D nucleome
Viral remodeling of the 4D nucleome Open
The dynamic spatial organization of genomes across time, referred to as the four-dimensional nucleome (4DN), is a key component of gene regulation and biological fate. Viral infections can lead to a reconfiguration of viral and host genome…
View article: Establishment of a Dual-Vector System for Gene Delivery Utilizing Prototype Foamy Virus
Establishment of a Dual-Vector System for Gene Delivery Utilizing Prototype Foamy Virus Open
Foamy viruses (FVs) are generally recognized as non-pathogenic, often causing asymptomatic or mild symptoms in infections. Leveraging these unique characteristics, FV vectors hold significant promise for applications in gene therapy. This …
View article: Characterization of a new CCCTC-binding factor binding site as a dual regulator of Epstein-Barr virus latent infection
Characterization of a new CCCTC-binding factor binding site as a dual regulator of Epstein-Barr virus latent infection Open
Distinct viral gene expression characterizes Epstein-Barr virus (EBV) infection in EBV-producing marmoset B-cell (B95-8) and EBV-associated gastric carcinoma (SNU719) cell lines. CCCTC-binding factor (CTCF) is a structural chromatin factor…
View article: Transcriptional Interplay between <i>Malassezia restricta</i> and <i>Staphylococcus</i> Species Co-Existing in the Skin Environment
Transcriptional Interplay between <i>Malassezia restricta</i> and <i>Staphylococcus</i> Species Co-Existing in the Skin Environment Open
Malassezia and Staphylococcus are the most dominant genera in human skin microbiome. To explore the inter-kingdom interactions between the two genera, we examined the transcriptional changes in Malassezia and Staphy…
View article: Topological implications of DNA tumor viral episomes
Topological implications of DNA tumor viral episomes Open
A persistent DNA tumor virus infection transforms normal cells into cancer cells by either integrating its genome into host chromosomes or retaining it as an extrachromosomal entity called episome. Viruses have evolved mechanisms for attac…
View article: CTCF-mediated Genomic Effects of BART Region on Epstein-Barr Virus Chromatin 3D Structure in Gastric Carcinoma Cells
CTCF-mediated Genomic Effects of BART Region on Epstein-Barr Virus Chromatin 3D Structure in Gastric Carcinoma Cells Open
EBV latent infection in gastric carcinoma (GC) cells is characterized by distinct viral gene expression programs. CCCTC-binding factor (CTCF) is a chromatin structural factor that has been involved in coordinated chromatin interactions bet…
View article: Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus Open
Epstein-Barr virus (EBV) genomes persist in latently infected cells as extrachromosomal episomes that attach to host chromosomes through the tethering functions of EBNA1, a viral encoded sequence-specific DNA binding protein. Here we emplo…
View article: Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization Open
View article: Architectural alterations of the fission yeast genome during the cell cycle
Architectural alterations of the fission yeast genome during the cell cycle Open
View article: Transcription factors mediate condensin recruitment and global chromosomal organization in fission yeast
Transcription factors mediate condensin recruitment and global chromosomal organization in fission yeast Open
View article: Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes
Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes Open