Explanipedia

The Change of Dopamine Transporter After Glucose Loading Is Associated With an Individual's Attitude Toward Sweet Foods in Healthy Young Males Open

Kyoungjune Pak, Seongho Seo · 2025

The dopamine transporter (DAT) mediates the reuptake of extracellular dopamine into presynaptic neurons. We investigated the effects of glucose loading on the striatal DAT in healthy young adults who underwent 18 F‐FP‐CIT PET scans and com…

Family Income Is Associated With Regional Brain Glucose Metabolism in Middle‐Aged Males Open

Kyoungjune Pak, Seunghyeon Shin, Hyun‐Yeol Nam, Keunyoung Kim, Myung Jun Lee , et al. · 2025

Socioeconomic status is a multifaceted construct that plays a prominent role in shaping our environment. This study investigated the associations between family income, education level, and brain glucose metabolism in middle‐aged males. We…

Investigating the association between maternal age and cerebral palsy incidence: A meta-analysis Open

Jae Meen Lee, Kyoungjune Pak · 2025

Background: Cerebral palsy (CP) is a group of nonprogressive motor and postural disorders resulting from early developmental brain injury. While maternal age is a known factor associated with CP risk, previous studies have shown inconsiste…

Is motor reserve associated with a rapid progression of Parkinson disease? Open

Myung Jun Lee, Kyoungjune Pak, Jae‐Hyeok Lee, Seok Jong Chung, Min Seok Baek · 2025

Background The motor reserve estimates (MRes) derived from a residual approach correlate with motor severity in Parkinson's disease (PD), leaving the independent effect of motor reserve on clinical outcomes unclear. Objective Investigate t…

Change in pericardial fat volume in postmenopausal women with papillary thyroid cancer undergoing thyrotropin suppressive therapy Open

Yun Kyung Jeon, Doohwa Kim, Mijin Kim, Bo Hyun Kim, Kyoungjune Pak , et al. · 2025

Korean Practice Guidelines for Gastric Cancer 2024: An Evidence-based, Multidisciplinary Approach (Update of 2022 Guideline) Open

In‐Ho Kim, Seung Joo Kang, Wonyoung Choi, An Na Seo, Bang Wool Eom , et al. · 2025

Gastric cancer is one of the most common cancers in both Korea and worldwide. Since 2004, the Korean Practice Guidelines for Gastric Cancer have been regularly updated, with the 4th edition published in 2022. The 4th edition was the result…

Correction: Clinical assessment and striatal dopaminergic activity in healthy controls and patients with Parkinson’s disease: a Bayesian approach Open

Seunghyeon Shin, Hyun‐Yeol Nam, Keunyoung Kim, Jihyun Kim, Myung Jun Lee , et al. · 2024

Family income is associated with regional brain glucose metabolism in middle-aged adults Open

Kyoungjune Pak, Seunghyeon Shin, Hyun‐Yeol Nam, Keunyoung Kim, Jihyun Kim , et al. · 2024

Socioeconomic status is a multifaceted construct that plays a prominent role in shaping our environment by defining our access to healthcare, nutrition, and enrichment, as well as represents social standing. Therefore, to address the effec…

Photoperiodicity in Glucose Metabolism in the Human Brain Open

Kyoungjune Pak, Seunghyeon Shin, Keunyoung Kim, Jihyun Kim, Hyun‐Yeol Nam , et al. · 2024

Photoperiodicity in the human brain function, which is a critical factor for social well-being, has been widely debated. In this study, 432 healthy males underwent fasting-state brain [ 18 F]fluorodeoxyglucose positron emission tomography …

Poor sleep quality is associated with decreased regional brain glucose metabolism in healthy middle-aged adults Open

Seunghyeon Shin, Ju Won Seok, Keunyoung Kim, Ji Hyun Kim, Hyun‐Yeol Nam , et al. · 2024

Sleep disturbance is associated with the development of neurodegenerative disease. We aimed to address the effects of sleep quality on brain glucose metabolism measured by ¹⁸F-Fl uorodeoxyglucose (¹⁸F-FDG) positron em…

Poor Sleep Quality is associated with Decreased Brain Glucose Metabolism in Healthy Middle-aged Adults Open

Seunghyeon Shin, Ju Won Seok, Keunyoung Kim, Jihyun Kim, Hyun‐Yeol Nam , et al. · 2024

Sleep disturbance is associated with the development of neurodegenerative disease. We aimed to address the effects of sleep quality on brain glucose metabolism measured by 18 F-Fluorodeoxyglucose ( 18 F-FDG) positron emission tomography (P…

Altered brain glucose metabolism in nicotine use but not in hazardous alcohol consumption or problem gambling of healthy middle-aged adults Open

Seunghyeon Shin, Keunyoung Kim, Jihyun Kim, Hyun‐Yeol Nam, Ju Won Seok , et al. · 2024

Objectives We aimed to determine whether chronic nicotine use, alcohol consumption, and gambling alters brain glucose metabolism. Methods We retrospectively analyzed data from 473 healthy men who participated in health checkups at Samsung …

Altered Brain Glucose Metabolism in COVID-19 disease: An activation likelihood estimation Meta-analysis Open

Dongju Kang, Hyunji Jung, Kyoungjune Pak · 2024

Purpose COVID-19, caused by the SARS-CoV-2 virus, has significantly altered modern society and lifestyles. We investigated its impact on brain glucose metabolism by meta-analyzing existing studies that utilized 18F-fluorodeoxyglucose (FDG)…

Glucose-loaded dopamine transporter is associated with mood altering effect of sweet foods and control over eating sweets Open

Kyoungjune Pak, Jihyun Kim, Keunyoung Kim, Seongho Seo, Myung Jun Lee · 2024

Dopamine transporter (DAT) mediates reuptake of extracellular dopamine into presynaptic neurons. We investigated the effects of glucose loading on striatal DAT in healthy young adults who underwent 18 F-FP-CIT positron emission tomography …

Anorexia nervosa is associated with higher brain mu-opioid receptor availability Open

Kyoungjune Pak, Jouni Tuisku, Henry K. Karlsson, Jussi Hirvonen, Eleni Rebelos , et al. · 2024

Anorexia nervosa (AN) is a severe psychiatric disorder, characterized by restricted eating, fear to gain weight, and a distorted body image. Mu-opioid receptor (MOR) functions as a part of complex opioid system and supports both homeostati…

Glucose metabolism and Radiodensity of Abdominal Adipose Tissue: A 5-year longitudinal study in a large PET cohort Open

Kyoungjune Pak, Severi Santavirta, Seunghyeon Shin, Hyun-Yeol Nam, Sven De Mæyer , et al. · 2024

Objective 18 F-Fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) allows the noninvasive assessment of glucose metabolism and radiodensity of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT). Re…

Brain dopamine receptor system is not altered in obesity: Bayesian and frequentist meta‐analyses Open

Kyoungjune Pak, Lauri Nummenmaa · 2023

Feeding induces dopamine release in the striatum, and a dysfunction of the dopaminergic reward system can lead to overeating, and obesity. Studies have reported inconsistent findings of dopamine receptor (DR) positron emission tomography s…

Comparison of UPDRS III score between young and late onset Parkinson disease after deep brain stimulation: A meta-analysis Open

Jae Meen Lee, Kyoungjune Pak · 2023

Purpose: Parkinson disease (PD) is a common age-related neurodegenerative disease. Subthalamic nucleus deep brain stimulation (DBS) is a safe and effective surgical treatment for medically resistant advanced PD. However, the relationship b…

Oncologic outcome of breast reconstruction after mastectomy in breast cancer: a systematic review and meta-analysis Open

Seok Kyung Kang, Dong Il Kim, Seungju Lee, Youn Joo Jung, Jung Yeol Seo , et al. · 2023

The data showed that BR after mastectomy had similar EFS and BCSS and better OS than mastectomy alone. Our meta-analysis suggests that BR is a practicable and safe treatment option for patients with breast cancer.

Author Correction: Association between visceral adipose tissue volume, measured using computed tomography, and cardio-metabolic risk factors Open

Wook Yi, Keunyoung Kim, Myungsoo Im, Soree Ryang, Eun Heui Kim , et al. · 2023

Author Correction: Effect of tamoxifen with or without gonadotropin-releasing hormone analog on DXA values in women with breast cancer Open

Eun Heui Kim, Yun Kyung Jeon, Kyoungjune Pak, Taewoo Kang, Kyung-Eun Kim , et al. · 2023

Corrigendum Open

Kyoungjune Pak · 2023

Brain Dopamine Receptor System is Not Altered in Obesity: Bayesian and Frequentist Meta-Analyses Open

Kyoungjune Pak, Lauri Nummenmaa · 2023

Background Feeding induces dopamine release in the striatum, and a dysfunction of the dopaminergic reward system can lead to overeating, and obesity. Studies have reported inconsistent findings of dopamine receptor (DR) positron emission t…

Neuropsychological, neuroimaging and autopsy findings of butane encephalopathy Open

Jaeseob Yun, Sung Hwan Jang, Huiran Cho, Myung Jun Lee, Na‐Yeon Jung , et al. · 2023

Corrigendum to ‘evaluation of the diagnostic performance of 18F-NaF positron emission tomography/computed tomography in patients with suspected ankylosing spondylitis according to the assessment of SpondyloArthritis International Society criteria’ by Seung Min Son et al’ [The Spine Journal 20/9 (2020) 1471-1479] Open

Seung Min Son, Keunyoung Kim, Kyoungjune Pak, Seong‐Jang Kim, Tae Sik Goh , et al. · 2023

Correction: Impact of 18F-FDG PET on the management of recurrent breast cancer: a meta-analysis Open

Kyoungjune Pak, Hai‐Jeon Yoon, Woosung Lim, Hyun Yul Kim · 2023

Correction: The association of DAT gene methylation with striatal DAT availability in healthy subjects Open

Kyoungjune Pak, Ju Won Seok, Hyun‐Yeol Nam, Seongho Seo, Myung Jun Lee , et al. · 2023

Correction to: Effects of animal handling on striatal DAT availability in rats Open

Seunghyeon Shin, Keunyoung Kim, Kyoungjune Pak, Hyun‐Yeol Nam, Hyung‐Jun Im , et al. · 2023

Correction: No effect of Parkinson’s disease-polygenic load on striatal density of dopaminergic neuron in healthy subjects Open

Kyoungjune Pak, Myung Jun Lee, Keunyoung Kim, In Joo Kim · 2023

Correction: Effect of sex on aging-related decline of dopamine transporter in healthy subjects Open

Seunghyeon Shin, Hyun‐Yeol Nam, Myung Jun Lee, Kyoungjune Pak, Keunyoung Kim , et al. · 2023

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