Explanipedia

Integrative multi-omics deciphers the potential mechanism and microbial biomarkers for lymph node metastasis in colorectal cancer Open

Min Seob Kwak, Jae Myung, Chang Woo Kim, Kyu Yeoun Won, Chang‐Il Hwang · 2025

Comparison of Biparametric MRI and Multiparametric MRI Using Split Dynamic MRI in Prostate Cancer Diagnosis Open

B. S. Kim, Dal Mo Yang, Hyun Cheol Kim, Sang Won Kim, Kyu Yeoun Won · 2025

Purpose To compare the diagnostic performance between biparametric MRI (bpMRI) and multiparametric MRI (mpMRI) using split dynamic MRI for detecting clinically significant prostate cancer (csPCa) with Prostate Imaging and Reporting Data Sy…

Imaging and Clinical Findings of Xanthogranulomatous Inflammatory Disease of Various Abdominal and Pelvic Organs: A Pictorial Essay Open

Se Jin Lee, Dal Mo Yang, Hyun Cheol Kim, Sang Won Kim, Kyu Yeoun Won , et al. · 2023

Xanthogranulomatous (XG) inflammatory disease is a rare benign disease involving various organs, including the gallbladder, bile duct, pancreas, spleen, stomach, small bowel, colon, appendix, kidney, adrenal gland, urachus, urinary bladder…

Myxoid Liposarcoma of the Breast Mimicking Phyllodes Tumor: A Case Report Open

Se Jin Lee, Jung Kyu Ryu, Kyu Yeoun Won, Sang‐Ah Han · 2023

Myxoid liposarcoma is an extremely rare malignant breast tumor. We report the case of a 44-year-old woman who had myxoid liposarcoma of the breast with a history of phyllodes tumor and describe the imaging findings on US, mammography, and …

Solitary Fibrous Tumor of Orbit: Changes of Tumor Size and Tumor Contrast Enhancement Open

Woo Seok Choe, In-Ki Park, Kyu Yeoun Won, Jae‐Ho Shin · 2022

Purpose: To report a case of solitary fibrous tumor of the orbit in a patient with changes in tumor size and contrast enhancement.Case summary: A 64-year-old male patient presented with dizziness, discomfort on eye movement, anosmia, and p…

Mesonephric-like Adenocarcinoma of the Uterine Corpus: Comprehensive Analyses of Clinicopathological, Molecular, and Prognostic Characteristics With Retrospective Review of 237 Endometrial Carcinoma Cases Open

Han Gyeol Kim, Hyunjin Kim, Min‐Kyung Yeo, Kyu Yeoun Won, Young Sun Kim , et al. · 2022

Uterine MLA is a highly aggressive gynecological malignancy, showing unique morphological and molecular features, frequent recurrences and metastases, as well as poor prognosis.

The antioncogenic effect of Beclin-1 and FOXP3 is associated with SKP2 expression in gastric adenocarcinoma Open

Hyung Kyung Kim, Kyu Yeoun Won, Sang‐Ah Han · 2021

An overexpression of S-phase kinase-associated protein 2 (SKP2) is frequently observed in human cancer progression and metastasis, and evidence suggests that SKP2 plays a proto-oncogenic role both in vitro and in vivo. However, the functio…

Adenosine A2A Receptor Agonist Polydeoxyribonucleotide Alleviates Interstitial Cystitis-Induced Voiding Dysfunction by Suppressing Inflammation and Apoptosis in Rats Open

Il‐Gyu Ko, Jun-Jang Jin, Lakkyong Hwang, Sang‐Hoon Kim, Chang‐Ju Kim , et al. · 2021

The conclusion of this experiment suggests the possibility that PDRN could be used as an effective therapeutic agent for IC.

ERG and nestin: useful markers of immature vessels and novel prognostic markers in renal cell carcinoma. Open

Eunkyung Han, Jiyoon Kim, Min-Jung Jung, Susie Chin, Ji‐Hye Lee , et al. · 2021

A loss of ERG and nestin expression is associated with tumor progression, and loss of ERG is a powerful prognostic marker for ccRCC.

Solitary, Endobronchial Metastasis from Renal Cell Carcinoma 20 Years after Nephrectomy Open

Min Ju Kim, Jung Im Kim, Kyu Yeoun Won, Han Na Lee · 2021

Late recurrence over 10 years after surgery and endobronchial metastasis are some of the specific biological behaviors of renal cell carcinoma (RCC). The current report describes a case of solitary endobronchial metastasis at a subsegmenta…

Clinical Significance of Receptor-Interacting Protein 3 and Parkin, Essential Molecules for Necroptosis, in Breast Cancer Open

Kyu Yeoun Won, Sun Young Min, Jeong-Yoon Song, Sung-Jig Lim, Sang‐Ah Han · 2021

Low RIP3 and high Parkin expression are associated with aggressive clinical features in breast cancer. RIP3, a molecular marker of necroptosis, is an independent factor associated with survival in breast cancer. Further in-depth studies ar…

Protective Effect of Polydeoxyribonucleotide Against CCl4-Induced Acute Liver Injury in Mice Open

Seung‐Hwan Lee, Kyu Yeoun Won, Sun-Hyung Joo · 2020

Purpose: Polydeoxyribonucleotide (PDRN) is a substance known to suppress inflammation and accelerate wound healing. In this experiment, the effect of PDRN treatment on carbon tetrachloride (CCl₄)-evoked acute liver injury (ALI) …

Mesonephric Adenocarcinoma of the Uterine Fundus Exhibiting High 18F-FDG Uptake Open

Hyung Kyung Kim, Kyu Yeoun Won, Chanwoo Kim · 2020

Mesonephric adenocarcinoma is a rare tumor that is considered to develop from mesonephric remnants of the female genital tract. This tumor usually occurs in the lateral wall of the uterine cervix. Herein, we present an exceptionally rare c…

Early Prediction of Tumor Response to Neoadjuvant Chemotherapy and Clinical Outcome in Breast Cancer Using a Novel FDG-PET Parameter for Cancer Stem Cell Metabolism Open

Chanwoo Kim, Sang‐Ah Han, Kyu Yeoun Won, Il Ki Hong, Deog Yoon Kim · 2020

Cancer stem cells (CSCs) contribute to chemoresistance and tumor relapse. By using the distinct metabolic phenotype of CSC, we designed novel PET parameters for CSC metabolism and investigated their clinical values. Patients with breast ca…

Clear cell chondrosarcoma of the talus in Von Hippel-Lindau disease: a rare tumor in an unusual location and uncommon co-presentation. Open

Min Jeong Song, Kyu Yeoun Won, Soonchan Park · 2020

Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited tumor syndrome. Clear cell chondrosarcoma (CCCS) is a rare variant of chondrosarcoma. Here, we report a case of CCCS in the talus occurring in a patient with VHL disease. A…

Circulating Tumor DNA in Saliva in an Orthotopic Head and Neck Cancer Mouse Model Open

Young‐Gyu Eun, YU JIN YOON, Kyu Yeoun Won, Young Chan Lee · 2019

In our orthotopic model, salivary ctDNA better reflected tumor development and recurrence than did plasma ctDNA.

Groin abnormalities: ultrasonographic and clinical findings Open

Dal Mo Yang, Hyun Cheol Kim, Sang Won Kim, Kyu Yeoun Won · 2019

Groin lesions can be classified as neoplastic or non-neoplastic. Neoplastic lesions include lipoma, epidermoid cyst, angiomyofibroblastoma-like tumor, liposarcoma, and synovial sarcoma, as well as metastases from lymphoma, neuroendocrine c…

Lower Sympathetic Nervous System Density and β-adrenoreceptor Expression Are Involved in Gastric Cancer Progression Open

Go Eun Bae, Hyun Soo Kim, Kyu Yeoun Won, Gou Young Kim, Ji‐Youn Sung , et al. · 2018

A lower SNS density and β-adrenoreceptor expression was associated with an aggressive oncogenic behavior including worse histological grade, advanced pT, and increased lymph node metastasis. SNS and β-adrenergic pathway are involved in the…

Growth pattern change of a benign clear cell ‘sugar’ tumor of the lung: Serial imaging surveillance over seven years Open

Eung Koo Yeon, Jung‐Ha Kim, Kyu Yeoun Won, Han Lee · 2018

Clear cell tumor of the lung is a rare benign mesenchymal tumor and only sporadic cases have been previously reported. The present study reports the case of a 58-year-old man who presented with an incidentally detected solitary pulmonary n…

Predictor of abnormal gallbladder ejection fraction in patients with atypical biliary pain Open

Jun Uk Lim, Kwang Ro Joo, Kyu Yeoun Won, Sung‐Jig Lim, Sun-Hyung Joo , et al. · 2017

Cholescintigraphy has traditionally been used as a tool to select patients with biliary pain for elective cholecystectomy. However, atypical biliary pain presents a clinical challenge and there is no literature evaluating the factors of th…

Recurrent maxillary sinus cancer with only adrenal metastasis Open

Hye Jung Chang, Joon-Young Hur, Kyu Yeoun Won, Boksoon Chang, Ha Yeon Lee · 2017

Maxillary sinus cancer is rare, and often presents as a locally advanced disease. Recurrence commonly occurs locoregionally, while fewer patients present with distant metastasis; the most common sites involved are the lung and bone. This r…

Anastomosing Hemangioma Involving the Para-Aortic Region: A Case Report Open

Jung Min Lee, Hyun Cheol Kim, Dal Mo Yang, Sang Won Kim, Kyu Yeoun Won · 2017

Analysis of NF-κ B and Clinical Prognostic Factors in Clear Cell Renal Cell Carcinoma Open

Young Lee, Jeonghyouk Choi, Dong‐Gi Lee, Koo Han Yoo, Gyeong Eun Min , et al. · 2016

Purpose A multi-subunit transcription factor NF-ÎºB is associated with anti-apoptotic signals in several cancers including renal cell carcinoma (RCC). In this study, we investigated whether the expression levels of the NF-ÎºB were related …

Successful en bloc resection of an esophageal hemangioma by combined EBL & EMR: a case report and technical review Open

Il Hyun Baek, Jung Won Jeon, Hyun Phil Shin, Jae Myung, Kwang Ro Joo , et al. · 2016

A 58-year-old male was diagnosed esophageal hemangioma during a endoscopy in regular examination. The patient was referred to the department of gastroenterology in our hospital to treatment. Combined endoscopic band ligation (EBL) and endo…

Subcutaneous Sarcoidosis Mimicking Cellulitis Open

Kyu Yeoun Won, So Young Park, Sang Hoon Lee · 2016

Sarcoidosis is a systemic disorder of unknown etiology characterized by noncaseating granulomas1. The lesion can have a reticular pattern similar to cellulitis. A 54-year-old woman with a 5-month history of focal swelling in the right med…

A Case of Fibrovascular Polyp of the Stomach: Sonographic and Computed Tomographic Findings Open

Yun Kyung Shin, Hyun Cheol Kim, Dal Mo Yang, Sang Won Kim, Sun Jung Rhee , et al. · 2016

Fibrovascular polyps are rare, pedunculated, tumor-like lesions that are usually found in the esophagus; occurrence in the stomach is very rare. To our knowledge, sonographic and CT findings of a fibrovascular polyp in the stomach have nev…

Chronic Intussusception Caused by Diffuse Large B-Cell Lymphoma in a 6-Year-Old Girl Presenting with Abdominal Pain and Constipation for 2 Months Open

Sun Hee Choi, Sang‐Ah Han, Kyu Yeoun Won · 2016

The classical triad of abdominal pain, vomiting, and bloody stool is absent in chronic intussusception for more than 2 weeks. Here, we report a 6-year-old female with recurrent abdominal pain for 2 months. Ultrasonography of the abdomen re…

Eosinophils in Colorectal Neoplasms Associated with Expression of CCL11 and CCL24 Open

Hyuck Cho, Sung‐Jig Lim, Kyu Yeoun Won, Go Eun Bae, Gou Young Kim , et al. · 2015

The discrepancy in CCL11 and CCL24 expression between glandular cells and stromal cells might shed light on how colorectal cancer evades the immune system, which would enable further development of immunotherapies that target these chemoki…

Expression of tumoral FOXP3 in gastric adenocarcinoma is associated with favorable clinicopathological variables and related with Hippo pathway. Open

J. H. Suh, Kyu Yeoun Won, Gou Young Kim, Go Eun Bae, Sung‐Jig Lim , et al. · 2015

FOXP3 is a transcription factor and well-known hallmark of immune suppressive T regulatory cells (Tregs). Recent studies indicate that, in addition to its association with Treg function in the immune system, FOXP3 plays an important role i…

High DBC1 (CCAR2) expression in gallbladder carcinoma is associated with favorable clinicopathological factors. Open

Kyu Yeoun Won, Hyuck Cho, Gou Young Kim, Sung‐Jig Lim, Go Eun Bae , et al. · 2015

There have been several studies on gallbladder carcinogenesis, and mutations of the KRAS, TP53, and CDKN2A genes have been reported in gallbladder carcinoma. The DBC1 gene (deleted in breast cancer 1) was initially cloned from region 8p21,…

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